PIPA596972
WWTR1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596972-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA596972 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
WWTR1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
WWTR1
Gene Alias
2310058J06Rik, 2610021I22Rik, C78399, DKFZp586I1419, FLJ27004, FLJ45718, Tafazzin, TAZ, transcriptional coactivator with PDZ binding motif, transcriptional co-activator with PDZ-binding motif, transcriptional coactivator with PDZ-binding motif, transcriptional co-activator with PDZ-binding motif (TA)Z, transcriptional co-activator with PDZ-binding motif (TAZ), WW domain containing transcription regulator 1, WW domain-containing transcription regulator protein 1, Wwtr1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
25937, 295062, 97064
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.88 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
Q9EPK5, Q9GZV5
Gene Symbols
WWTR1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human TAZ (NP_0562871)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: SW480; Cellular Location: Cytoplasm, Nucleus Immunogen sequence: MNPASAPPPL PPPGQQVIHV TQDLDTDLEA LFNSVMNPKP SSWRKKILPE SFFKEPDSGS HSRQSSTDSS GGHPGPRLAG GAQHVRSHSS PASLQLGTGA GAAGSPAQQH AHLRQQSYDV TDELPLPPGW EMTFTATGQR YFLNHIEKIT TWQDPRKAMN QPLNHMNLHP AVSSTPVPQR SMAVSQPNLV MNHQHQQQMA PSTLSQQNHP TQNPPAGLMS MPNALTTQQQ WW domain-containing transcription regulator protein 1 (WWTR1) is a transcriptional coactivator which acts as a downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor supression by restricting proliferation and promoting apoptosis
- The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1
- In turn, MOB1 phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
- WWTR1 enhances PAX8 and NKX2-1/TTF1-dependent gene activation
- WWTR1 regulates the nuclear accumulation of SMADS and has a key role in coupling them to the transcriptional machinery such as the mediator complex
- WWTR1 also regulates embryonic stem-cell self-renewal and promotes cell proliferation and epithelial-mesenchymal transition.
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Antigen: WWTR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: WWTR1
Gene Alias: 2310058J06Rik, 2610021I22Rik, C78399, DKFZp586I1419, FLJ27004, FLJ45718, Tafazzin, TAZ, transcriptional coactivator with PDZ binding motif, transcriptional co-activator with PDZ-binding motif, transcriptional coactivator with PDZ-binding motif, transcriptional co-activator with PDZ-binding motif (TA)Z, transcriptional co-activator with PDZ-binding motif (TAZ), WW domain containing transcription regulator 1, WW domain-containing transcription regulator protein 1, Wwtr1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 25937, 295062, 97064
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.88 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q9EPK5, Q9GZV5
Gene Symbols: WWTR1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human TAZ (NP_0562871)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
WWTR1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
WWTR1
Gene Alias:
2310058J06Rik, 2610021I22Rik, C78399, DKFZp586I1419, FLJ27004, FLJ45718, Tafazzin, TAZ, transcriptional coactivator with PDZ binding motif, transcriptional co-activator with PDZ-binding motif, transcriptional coactivator with PDZ-binding motif, transcriptional co-activator with PDZ-binding motif (TA)Z, transcriptional co-activator with PDZ-binding motif (TAZ), WW domain containing transcription regulator 1, WW domain-containing transcription regulator protein 1, Wwtr1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
25937, 295062, 97064
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.88 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q9EPK5, Q9GZV5
Gene Symbols:
WWTR1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human TAZ (NP_0562871)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: IL1F6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL36A
Gene Alias: FIL1, FIL1 epsilon, FIL1(EPSILON), Fil1e, Fil1epsilon, IL-1 epsilon, IL1(EPSILON), Il1e, Il1f6, IL-1F6, IL-1F6 (FIL-1-epsilon), Il1f9, Il1h1, IL-1H1, IL1RP2, Il36a, interleukin 1, interleukin 1 family, member 6, interleukin 1 family, member 6 (epsilon), interleukin 1 family, member 9, interleukin 1, epsilon, interleukin 36, alpha, interleukin-1 epsilon, Interleukin-1 family member 6, interleukin-1 homolog 1, Interleukin-36, Interleukin-36 alpha
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27179, 296541, 54448
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.8 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q9JLA2, Q9UHA7
Gene Symbols: Il1f6, IL36A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human IL36A (NP_0552551)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
IL1F6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL36A
Gene Alias:
FIL1, FIL1 epsilon, FIL1(EPSILON), Fil1e, Fil1epsilon, IL-1 epsilon, IL1(EPSILON), Il1e, Il1f6, IL-1F6, IL-1F6 (FIL-1-epsilon), Il1f9, Il1h1, IL-1H1, IL1RP2, Il36a, interleukin 1, interleukin 1 family, member 6, interleukin 1 family, member 6 (epsilon), interleukin 1 family, member 9, interleukin 1, epsilon, interleukin 36, alpha, interleukin-1 epsilon, Interleukin-1 family member 6, interleukin-1 homolog 1, Interleukin-36, Interleukin-36 alpha
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27179, 296541, 54448
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.8 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q9JLA2, Q9UHA7
Gene Symbols:
Il1f6, IL36A
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-158 of human IL36A (NP_0552551)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Ninein
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NIN
Gene Alias: 3110068G20Rik, AI385615, AU024711, glycogen synthase kinase 3 beta-interacting protein, GSK3B-interacting protein, hNinein, KIAA1565, mKIAA1565, Nin, Ninein, ninein (GSK3B interacting protein), ninein centrosomal protein, SCKL7
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18080, 299117, 51199
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.21 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q61043, Q8N4C6
Gene Symbols: NIN
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human NIN (NP_8919911)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Ninein
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NIN
Gene Alias:
3110068G20Rik, AI385615, AU024711, glycogen synthase kinase 3 beta-interacting protein, GSK3B-interacting protein, hNinein, KIAA1565, mKIAA1565, Nin, Ninein, ninein (GSK3B interacting protein), ninein centrosomal protein, SCKL7
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18080, 299117, 51199
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.21 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q61043, Q8N4C6
Gene Symbols:
NIN
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human NIN (NP_8919911)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: SEMA4C
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SEMA4C
Gene Alias: AI426163, FLJ20369, KIAA1739, MGC126382, MGC126383, M-Sema F, M-SEMA-F, RGD1562837, S4c, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C, Sema I, SEMA4C, SEMACL1, SEMAF, SEMAI, semaphorin 4C, semaphorin-4C, Semaphorin-C-like 1, UNQ5855/PRO34487
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20353, 54910
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.57 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q64151, Q9C0C4
Gene Symbols: SEMA4C
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 749-833 of human SEMA4C (NP_0602594)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SEMA4C
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SEMA4C
Gene Alias:
AI426163, FLJ20369, KIAA1739, MGC126382, MGC126383, M-Sema F, M-SEMA-F, RGD1562837, S4c, sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C, Sema I, SEMA4C, SEMACL1, SEMAF, SEMAI, semaphorin 4C, semaphorin-4C, Semaphorin-C-like 1, UNQ5855/PRO34487
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20353, 54910
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.57 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q64151, Q9C0C4
Gene Symbols:
SEMA4C
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 749-833 of human SEMA4C (NP_0602594)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG