PIPA597209

NUMB Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597209-Each-of-1 In Stock ₹ 44,705.10

PIPA597209 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

NUMB

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Numb

Gene Alias

c14_5527, C14orf41, h-Numb, mnb, m-Nb, m-numb, Nb, NUMB, NUMB endocytic adaptor protein, numb gene homolog, numb gene homolog (Drosophila), numb homolog, numb homolog (Drosophila), NUMB isoform 3, Numb variant 1, Numb variant 2, NUMB, endocytic adaptor protein, protein numb homolog, Protein S171, PTB domain protein, S171

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18222, 29419, 8650

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1.51 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.

P49757, Q2LC84, Q9QZS3

Gene Symbols

Numb

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 521-640 of human NUMB (NP_0037353)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: SQMVANVFGT AGHPQAAHPH QSPSLVRQQT FPHYEASSAT TSPFFKPPAQ HLNGSAAFNG VDDGRLASAD RHTEVPTGTC PVDPFEAQWA ALENKSKQRT NPSPTNPFSS DLQKTFEIEL; Positive Samples: HeLa, LO2, U-87MG, HT-1080, SW480, A-549, Rat liver; Cellular Location: Membrane, Peripheral membrane protein Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells
  • Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex
  • NUMB is also expressed in postmitotic neurons and plays a role in axonal growth
  • Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.

Compare Similar Items

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Thermo Scientific

PIPA597209

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Antigen:
NUMB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Numb

Gene Alias:
c14_5527, C14orf41, h-Numb, mnb, m-Nb, m-numb, Nb, NUMB, NUMB endocytic adaptor protein, numb gene homolog, numb gene homolog (Drosophila), numb homolog, numb homolog (Drosophila), NUMB isoform 3, Numb variant 1, Numb variant 2, NUMB, endocytic adaptor protein, protein numb homolog, Protein S171, PTB domain protein, S171

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18222, 29419, 8650

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P49757, Q2LC84, Q9QZS3

Gene Symbols:
Numb

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 521-640 of human NUMB (NP_0037353)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA597210

--


Antigen:
LINGO1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LINGO1

Gene Alias:
4930471K13Rik, AV148400, LERN1, leucine rich repeat and Ig domain containing 1, leucine rich repeat neuronal 6A, leucine-rich repeat, leucine-rich repeat and immunoglobulin domain-containing protein 1, Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1, leucine-rich repeat neuronal 6A, leucine-rich repeat neuronal protein 1, Leucine-rich repeat neuronal protein 6A, Lingo1, LINGO-1, LRRN6A, UNQ201, UNQ201/PRO227

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
235402, 84894

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q96FE5, Q9D1T0

Gene Symbols:
LINGO1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 42-240 of human LINGO1 (NP_1161974)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA597211

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Antigen:
NFIX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NFIX

Gene Alias:
CCAAT-binding transcription factor, CCAAT-box-binding transcription factor, CTF, KIAA1439, MRSHSS, NF1A, NF1-A, NF1-B, NF1-C, NF1-X, NF1-X1 protein, NFI, NF-I/A, NF-I/B, NF-I/C, NF-I/X, NFIA, NFI-A, NFIB, NFI-B, NFIC, NFI-C, NFIX, NFI-X, Nuclear factor 1 X-type, Nuclear factor 1/A, Nuclear factor 1/B, Nuclear factor 1/C, nuclear factor 1/X, nuclear factor I X, Nuclear factor I/A, Nuclear factor I/B, Nuclear factor I/C, nuclear factor I/X, nuclear factor I/X (CCAAT-binding transcription factor), SOTOS2, TGGCA-binding protein

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18032, 4784

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P70257, Q14938

Gene Symbols:
NFIX

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-260 of human NFIX (NP_0024922)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA597212

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Antigen:
IST1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IST1

Gene Alias:
2400003C14Rik, AW536298, fb16b04, hIST1, hypothetical protein LOC321460, hypothetical protein LOC508900, increased sodium tolerance 1 homolog, increased sodium tolerance 1 homolog (yeast), IST1, IST1 factor associated with ESCRT-III, IST1 homolog, IST1, endosomal sorting complex required for transport-III component, IST1, ESCRT-III associated factor, IST1-like protein, Kiaa0174, KIAA0174-like protein, MAPK activating protein PM28, MGC117220, mKIAA0174, OLC1, overexpressed in lung cancer 1, pm28, putative MAPK-activating protein PM28, RGD1307799, wu:fb16b04, wu:fi89e07, zgc:55671

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
307833, 71955, 9798

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.87 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P53990, Q568Z6, Q9CX00

Gene Symbols:
IST1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human IST1 (NP_0012579061)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG