PIPA597244

NOXA Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA597244-Each-of-1 In Stock ₹ 44,191.74

PIPA597244 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

NOXA

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PMAIP1

Gene Alias

adult T cell leukemia-derived PMA-responsive, APR, Immediate-early-response protein APR, Noxa, Phorbol-12-myristate-13-acetate-induced protein 1, PMA-ind, PMA-induced protein 1, Pmaip1, Protein Noxa

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

492821, 5366, 58801

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

0.88 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q13794, Q5U777, Q9JM54

Gene Symbols

PMAIP1

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-54 of human PMAIP1 (NP_0669501)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: MPGKKARKNA QPSPARAPAE LEVECATQLR RFGDKLNFRQ KLLNLISKLF CSGT; Positive Samples: Jurkat, HeLa, HT-1080, SKOV3, BT-474; Cellular Location: Mitochondrion Apoptosis is related to many diseases and development
  • The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes including p53R2, p53AIP1, and PUMA
  • A new p53 target gene, Noxa, was recently identified, which encodes a protein belonging to the subfamily of BH3-only proapoptic proteins
  • Noxa and PUMA are both transcriptional targets of p53 and BH3-only proteins
  • X-ray irradiation increased p53-dependent Noxa mRNA and protein levels
  • Noxa, when ectopically expressed, interacted with anti-apoptotic Bcl-2 family members, resulting in the activation of caspase-9
  • Noxa, like PUMA, localized to mitochondria and induces apoptosis in response to p53
  • Noxa and PUMA may represent direct mediators of p53-induced apoptosis
  • Increased levels of p53 and its target gene Noxa was found in the impaired tumor development.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA597244

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Antigen:
NOXA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PMAIP1

Gene Alias:
adult T cell leukemia-derived PMA-responsive, APR, Immediate-early-response protein APR, Noxa, Phorbol-12-myristate-13-acetate-induced protein 1, PMA-ind, PMA-induced protein 1, Pmaip1, Protein Noxa

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
492821, 5366, 58801

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.88 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q13794, Q5U777, Q9JM54

Gene Symbols:
PMAIP1

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-54 of human PMAIP1 (NP_0669501)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597245

--


Antigen:
MICB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MICB

Gene Alias:
MHC class I chain-related protein B, MHC class I mic-B antigen, MHC class I polypeptide-related sequence B, MHC class I-like located near the LRC, 2, MHC class I-like molecule PERB11.2-IMX, MHC I like leukocyte 2, MICB, MIC-B, Mill2, Mill2 gene for MHC class I-like located near the LRC, 2, exon 3, partial cds, strain:LEW.1lm1, PERB11.2, sMICB, soluble MICB, stress inducible class I homolog

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4277

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.97 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q29980

Gene Symbols:
MICB

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-108 of human MICB (NP_0059222)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597246

--


Antigen:
MTERFD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTERF3

Gene Alias:
2410017I18Rik, Cgi12, CGI-12, Mitochondrial transcription termination factor 3, MTERF domain containing 1, mTERF domain-containing protein 1, mitochondrial, Mterf3, MTERFD1, transcription termination factor 3, mitochondrial

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
51001, 66410

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.35 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q8R3J4, Q96E29

Gene Symbols:
MTERF3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 69-300 of human MTERFD1 (NP_0570263)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597247

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Antigen:
ADCY2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADCY2

Gene Alias:
3',5'-cyclic AMP synthetase, AC2, Adcy2, adenylate cyclase 2, adenylate cyclase 2 (brain), adenylate cyclase II, adenylate cyclase type 2, Adenylate cyclase type II, adenylyl cyclase 2, ATP pyrophosphate-lyase 2, HBAC2, KIAA1060, mKIAA1060, type II adenylate cyclase, type II adenylyl cyclase

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
108, 210044, 81636

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P26769, Q08462, Q80TL1

Gene Symbols:
ADCY2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 430-600 of human ADCY2 (NP_0654332)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG