PIPA597307
SOCS6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597307-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA597307 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
SOCS6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SOCS6
Gene Alias
1500012M23Rik, 5830401B18Rik, AI447482, Cis4, CIS-4, Cish4, cytokine inducible SH2-containing protein 4, cytokine inducible SH2-containing protein CIS4, cytokine-inducible SH2 protein 4, HSPC060, SH2 domain containing SOCS box protein SOCS6, SOCS4, SOCS-4, Socs6, SOCS-6, SSI4, STAI4, STAT induced STAT inhibitor-4, STATI4, Suppressor of cytokine signaling 4, suppressor of cytokine signaling 6
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
54607, 9306
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.55 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
O14544, Q9JLY0
Gene Symbols
SOCS6
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SOCS6 (NP_0042232)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MKKISLKTLR KSFNLNKSKE ETDFMVVQQP SLASDFGKDD SLFGSCYGKD MASCDINGED EKGGKNRSKS ESLMGTLKRR LSAKQKSKGK AGTPSGSSAD EDTFSSSSAP IVFKDVRAQR PIRSTSLRSH HYSPAPWPLR PTNSEETCIK MEVRVKALVH SSSPSPALNG VRKDFHDLQS ETTCQEQANS LKSSASHNGD LHLHLDEHVP; Positive Samples: A-549, Mouse heart, Mouse kidney The eight members of the recently identified Suppressor of Cytokines Signaling (SOCS) family are SOCS1, SOCS2, SOCS3, SOCS4, SOCS5, SOCS6, SOCS7, and CIS
- Structurally the SOCS proteins are composed of an N- terminal region of variable length and amino acid composition, a central SH2 domain, and a C-terminal motif called the SOCS box
- The SOCS proteins appear to form part of a classical negative feedback loop that regulates cytokine signal transduction
- Transcription of each of the SOCS genes occurs rapidly in vitro and in vivo in response to cytokines, and once produced, the various members of the SOCS family appear to inhibit signaling in different ways
- SOCS1 and SOCS6 interact with the insulin receptor (IR) when expressed in human hepatoma cells (HepG2) or in rat hepatoma cells overexpressing human IR
- SOCS1 and SOCS6 inhibit insulin-dependent activation of ERK1/2 and protein kinase B in vivo and IR- directed phosphorylation of IRS1 in vitro
- These results suggest that SOCS proteins may be inhibitors of IR signalling and could mediate cytokine-induced insulin resistance and contribute to the pathogenesis of type II diabetes.
Compare Similar Items
Show Difference
Antigen: SOCS6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SOCS6
Gene Alias: 1500012M23Rik, 5830401B18Rik, AI447482, Cis4, CIS-4, Cish4, cytokine inducible SH2-containing protein 4, cytokine inducible SH2-containing protein CIS4, cytokine-inducible SH2 protein 4, HSPC060, SH2 domain containing SOCS box protein SOCS6, SOCS4, SOCS-4, Socs6, SOCS-6, SSI4, STAI4, STAT induced STAT inhibitor-4, STATI4, Suppressor of cytokine signaling 4, suppressor of cytokine signaling 6
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54607, 9306
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.55 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O14544, Q9JLY0
Gene Symbols: SOCS6
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SOCS6 (NP_0042232)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
SOCS6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SOCS6
Gene Alias:
1500012M23Rik, 5830401B18Rik, AI447482, Cis4, CIS-4, Cish4, cytokine inducible SH2-containing protein 4, cytokine inducible SH2-containing protein CIS4, cytokine-inducible SH2 protein 4, HSPC060, SH2 domain containing SOCS box protein SOCS6, SOCS4, SOCS-4, Socs6, SOCS-6, SSI4, STAI4, STAT induced STAT inhibitor-4, STATI4, Suppressor of cytokine signaling 4, suppressor of cytokine signaling 6
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54607, 9306
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.55 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O14544, Q9JLY0
Gene Symbols:
SOCS6
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human SOCS6 (NP_0042232)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: RGS14
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rgs14
Gene Alias: rap1/rap2 interacting protein, RAP1/RAP2-interacting protein, Regulator of G-protein signaling 14, regulator of G-protein signalling 14, RGS14, RGSE, RPIP1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10636, 114705, 51791
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.4 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O08773, O43566, P97492
Gene Symbols: Rgs14
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 230-510 of human RGS14 (NP_0064712)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
RGS14
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rgs14
Gene Alias:
rap1/rap2 interacting protein, RAP1/RAP2-interacting protein, Regulator of G-protein signaling 14, regulator of G-protein signalling 14, RGS14, RGSE, RPIP1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10636, 114705, 51791
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.4 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O08773, O43566, P97492
Gene Symbols:
Rgs14
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 230-510 of human RGS14 (NP_0064712)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: FBXO4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FBXO4
Gene Alias: 1700096C12Rik, AI851261, AW494535, F-box only protein 4, F-box protein 4, F-box protein Fbx4, FBX4, Fbxo4
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 106052, 26272
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.12 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q8CHQ0, Q9UKT5
Gene Symbols: FBXO4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 138-387 of human FBXO4 (NP_0363081)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
FBXO4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FBXO4
Gene Alias:
1700096C12Rik, AI851261, AW494535, F-box only protein 4, F-box protein 4, F-box protein Fbx4, FBX4, Fbxo4
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
106052, 26272
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.12 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q8CHQ0, Q9UKT5
Gene Symbols:
FBXO4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 138-387 of human FBXO4 (NP_0363081)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: eIF3k
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EIF3K
Gene Alias: 1200009C21Rik, ARG134, eIF-3 p25, eIF-3 p28, eIF3k, EIF3-p28, Eif3s12, eukaryotic translation initiation factor 3 subunit 12, Eukaryotic translation initiation factor 3 subunit K, eukaryotic translation initiation factor 3, subunit 12, eukaryotic translation initiation factor 3, subunit K, HSPC029, M9, MSTP001, muscle specific, muscle-specific gene M9 protein, PLAC24, PLAC-24, PRO1474, PTD001
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27335, 292762, 73830
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.22 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q9DBZ5, Q9UBQ5
Gene Symbols: EIF3K
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human EIF3K (NP_0373661)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
eIF3k
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EIF3K
Gene Alias:
1200009C21Rik, ARG134, eIF-3 p25, eIF-3 p28, eIF3k, EIF3-p28, Eif3s12, eukaryotic translation initiation factor 3 subunit 12, Eukaryotic translation initiation factor 3 subunit K, eukaryotic translation initiation factor 3, subunit 12, eukaryotic translation initiation factor 3, subunit K, HSPC029, M9, MSTP001, muscle specific, muscle-specific gene M9 protein, PLAC24, PLAC-24, PRO1474, PTD001
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27335, 292762, 73830
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.22 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q9DBZ5, Q9UBQ5
Gene Symbols:
EIF3K
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-218 of human EIF3K (NP_0373661)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG