PIPA597354
Phospho-Histone H2A.X (Ser139) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597354-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA597354 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
Phospho-Histone H2A.X (Ser139)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
15270, 3014, 500987
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.25 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
P16104, P27661
Gene Symbols
H2AX
Immunogen
A synthetic phosphorylated peptide around S139 of human Histone H2AX (NP_0020961)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive Samples: Jurkat, NIH/3T3, C6; Cellular Location: Chromosome, Nucleus Immunogen sequence: QASQEY Histone H2A.X (H2AX) is a member of the histone H2A family which is one of the four core histones making up the nucleosome core particle
- In eukaryotes, DNA double strand breaks (DSBs) have been shown to trigger the phosphorylation of serine 139 at the carboxy terminus of histone H2AX resulting in gamma-H2AX
- The phosphorylation of H2AX can be detected by Western blotting or immunofluorescence, revealing the frequency of DSBs
- The phosphatidylinositol 3-kinases have been implicated in H2AX phosphorylation, but it is unclear if ATM is the primary H2AX kinase or if other members of the family such as DNA-PK and ATR contribute in a similar manner
- Structurally, H2A.x contains 143 amino acid residues
- Histone H2A.X is considered a basal histone, being synthesized in G1 as well as in S-phase, and its mRNA contains polyA addition motifs and a polyA tail along with the conserved stem-loop and U7 binding sequences involved in the processing and stability of replication type histone mRNAs
- There are two forms of Histone H2A.X mRNA, one about 1600 bases long and contains polyA; the other about 575 bases long, lacking polyA
- The short form behaves as a replication type histone mRNA, while the longer behaves as a basal type histone mRNA
- Histone H2A.X maps to the 11q23.2-q23.3 region of the human chromosome
- Histone H2A.x contributes to histone-formation and therefore the structure of DNA
- Histone H2A variant H2A.x specifically regulates the interaction of MDC1 (mediator of DNA damage checkpoint protein 1), a DNA repair protein to the sites of DNA damage.
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Antigen: Phospho-Histone H2A.X (Ser139)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014, 500987
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.25 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: A synthetic phosphorylated peptide around S139 of human Histone H2AX (NP_0020961)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Histone H2A.X (Ser139)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014, 500987
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
A synthetic phosphorylated peptide around S139 of human Histone H2AX (NP_0020961)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-STAT1 (Ser727)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT1
Gene Alias: 2010005J02Rik, AA408197, CANDF7, DD6G4-4, DKFZp686B04100, IMD31A, IMD31B, IMD31C, ISGF-3, LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta, OTTHUMP00000165046, OTTHUMP00000205845, signal transducer and activator of transcription 1, signal transducer and activator of transcription 1, 91kD, signal transducer and activator of transcription 1, 91kDa, signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription-1, STAT, STAT 1, STAT1, STAT-1, stat1 alpha, STAT91, transcription factor ISGF-3, transcription factor ISGF-3 components p91/p84
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20846, 25124, 6772
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1.42 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P42224, P42225
Gene Symbols: STAT1
Immunogen: A synthetic phosphorylated peptide around S727 of human STAT1 (NP_0093301)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-STAT1 (Ser727)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT1
Gene Alias:
2010005J02Rik, AA408197, CANDF7, DD6G4-4, DKFZp686B04100, IMD31A, IMD31B, IMD31C, ISGF-3, LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta, OTTHUMP00000165046, OTTHUMP00000205845, signal transducer and activator of transcription 1, signal transducer and activator of transcription 1, 91kD, signal transducer and activator of transcription 1, 91kDa, signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription-1, STAT, STAT 1, STAT1, STAT-1, stat1 alpha, STAT91, transcription factor ISGF-3, transcription factor ISGF-3 components p91/p84
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20846, 25124, 6772
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1.42 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P42224, P42225
Gene Symbols:
STAT1
Immunogen:
A synthetic phosphorylated peptide around S727 of human STAT1 (NP_0093301)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-SRC (Tyr529)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SRC
Gene Alias: ASV, AW259666, csrc, c-SRC, c-src protein, C terminus, EC 2.7.10.2, fc54g04, Neuronal proto-oncogene tyrosine-protein kinase Src, non-tyrosine protein kinase, ORF, OTTHUMP00000174476, OTTHUMP00000174477, OTTHUMP00000174478, p60-Src, p60-Src-1, PP60C-SCR, pp60c-src, pp60src, pp60v-src, protein-tyrosine kinase, proto-oncogene c-Src, protooncogene SRC, Rous sarcoma, Proto-oncogene tyrosine-protein kinase Src, Rous sarcoma oncogene, RP5-823N20.1, sb:cb864, SDR, src, src downstream region, src oncogene, SRC proto-oncogene, non-receptor tyrosine kinase, SRC proto-oncogene, non-receptor tyrosine kinase L homeolog, SRC proto-oncogene, non-receptor tyrosine kinase S homeolog, src.L, src.S, SRC1, src-1, src1-A, src-a, src-b, THC6, transforming protein, tyrosine kinase pp60c-src, tyrosine protein kinase c-src, tyrosine protein kinase pp60-c-src, tyrosine-protein kinase SRC-1, Unknown, v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, v-src sarcoma viral oncogene, wu:fc54g04, XELAEV_18046582mg, xsrc
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20779, 6714, 83805
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.08 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: P05480, P12931, Q9WUD9
Gene Symbols: SRC
Immunogen: A synthetic phosphorylated peptide around Y529 of human Src (NP_0054081)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-SRC (Tyr529)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SRC
Gene Alias:
ASV, AW259666, csrc, c-SRC, c-src protein, C terminus, EC 2.7.10.2, fc54g04, Neuronal proto-oncogene tyrosine-protein kinase Src, non-tyrosine protein kinase, ORF, OTTHUMP00000174476, OTTHUMP00000174477, OTTHUMP00000174478, p60-Src, p60-Src-1, PP60C-SCR, pp60c-src, pp60src, pp60v-src, protein-tyrosine kinase, proto-oncogene c-Src, protooncogene SRC, Rous sarcoma, Proto-oncogene tyrosine-protein kinase Src, Rous sarcoma oncogene, RP5-823N20.1, sb:cb864, SDR, src, src downstream region, src oncogene, SRC proto-oncogene, non-receptor tyrosine kinase, SRC proto-oncogene, non-receptor tyrosine kinase L homeolog, SRC proto-oncogene, non-receptor tyrosine kinase S homeolog, src.L, src.S, SRC1, src-1, src1-A, src-a, src-b, THC6, transforming protein, tyrosine kinase pp60c-src, tyrosine protein kinase c-src, tyrosine protein kinase pp60-c-src, tyrosine-protein kinase SRC-1, Unknown, v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, v-src sarcoma viral oncogene, wu:fc54g04, XELAEV_18046582mg, xsrc
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20779, 6714, 83805
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.08 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
P05480, P12931, Q9WUD9
Gene Symbols:
SRC
Immunogen:
A synthetic phosphorylated peptide around Y529 of human Src (NP_0054081)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Stathmin 1 (Ser16)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Stmn1
Gene Alias: 19k, C1orf215, I79_017954, Lag, LAP18, leukemia associated phosphoprotein p18, leukemia-associated cytosolic phosphoprotein stathmin, leukemia-associated gene protein, Leukemia-associated phosphoprotein p18, metablastin, Oncoprotein 18, Op18, OTTHUMP00000008529, OTTHUMP00000008531, P18, P19, phosphoprotein 19, phosphoprotein p19, Pig, pp17, Pp18, Pp19, Pr22, Pr22 protein, Prosolin, Protein Pr22, RP1-125I3.5, SMN, Stathmin, stathmin 1, stathmin 1 variant, stathmin 1/oncoprotein 18, Stmn1, STN1, testicular tissue protein Li 189, transmembrane protein C1orf215
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16765, 3925
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.16 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P16949, P54227
Gene Symbols: Stmn1
Immunogen: A synthetic phosphorylated peptide around S16 of human Stathmin 1 (NP_0011389261)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Stathmin 1 (Ser16)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Stmn1
Gene Alias:
19k, C1orf215, I79_017954, Lag, LAP18, leukemia associated phosphoprotein p18, leukemia-associated cytosolic phosphoprotein stathmin, leukemia-associated gene protein, Leukemia-associated phosphoprotein p18, metablastin, Oncoprotein 18, Op18, OTTHUMP00000008529, OTTHUMP00000008531, P18, P19, phosphoprotein 19, phosphoprotein p19, Pig, pp17, Pp18, Pp19, Pr22, Pr22 protein, Prosolin, Protein Pr22, RP1-125I3.5, SMN, Stathmin, stathmin 1, stathmin 1 variant, stathmin 1/oncoprotein 18, Stmn1, STN1, testicular tissue protein Li 189, transmembrane protein C1orf215
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16765, 3925
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.16 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P16949, P54227
Gene Symbols:
Stmn1
Immunogen:
A synthetic phosphorylated peptide around S16 of human Stathmin 1 (NP_0011389261)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG