PIPA597358
Phospho-BRCA1 (Ser1423) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597358-Each-of-1 | In Stock | ₹ 44,619.54 |
PIPA597358 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,619.54
GST (18%): ₹ 8,031.517
Total Price: ₹ 52,651.057
Antigen
Phospho-BRCA1 (Ser1423)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
BRCA1
Gene Alias
brca 1, Brca1, brca-1, BRCA1, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, breast cancer 1 early onset, breast cancer 1, early onset, breast cancer associated 1, breast cancer type 1 susceptibility protein, Breast cancer type 1 susceptibility protein homolog, BROVCA1, BROVCA12, Delta772-3095, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, OTTHUMP00000212147, OTTHUMP00000212148, OTTHUMP00000212149, OTTHUMP00000212150, OTTHUMP00000212151, OTTHUMP00000212155, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12189, 497672, 672
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.81 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
O54952, P38398, P48754
Gene Symbols
BRCA1
Immunogen
A synthetic phosphorylated peptide around S1423 of human BRCA1 (NP_0092251)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: HGSQP; Positive Samples: HT-29; Cellular Location: Chromosome, Cytoplasm, Cytoplasm, Nucleus BRCA1 (breast and ovarian cancer susceptibility protein 1) is a nuclear phosphoprotein that plays a role in maintaining genomic stability and acts as a tumor suppressor in combination with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as BASC (for BRCA1 associated genome surveillance complex)
- BRCA1 associates with RNA polymerase II, and through the C terminal domain, also interacts with histone deacetylase complex
- The BRCA1 protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination
- Mutations in the BRCA1 gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers
- Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene
- Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described
- A related pseudogene, which is also located on chromosome 17, has been identified.
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Antigen: Phospho-BRCA1 (Ser1423)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BRCA1
Gene Alias: brca 1, Brca1, brca-1, BRCA1, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, breast cancer 1 early onset, breast cancer 1, early onset, breast cancer associated 1, breast cancer type 1 susceptibility protein, Breast cancer type 1 susceptibility protein homolog, BROVCA1, BROVCA12, Delta772-3095, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, OTTHUMP00000212147, OTTHUMP00000212148, OTTHUMP00000212149, OTTHUMP00000212150, OTTHUMP00000212151, OTTHUMP00000212155, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12189, 497672, 672
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.81 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O54952, P38398, P48754
Gene Symbols: BRCA1
Immunogen: A synthetic phosphorylated peptide around S1423 of human BRCA1 (NP_0092251)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-BRCA1 (Ser1423)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BRCA1
Gene Alias:
brca 1, Brca1, brca-1, BRCA1, DNA repair associated, BRCA1/BRCA2-containing complex, subunit 1, BRCAI, BRCC1, breast and ovarian cancer susceptibility protein 1, breast and ovarian cancer sususceptibility protein 1, breast cancer 1, breast cancer 1 early onset, breast cancer 1, early onset, breast cancer associated 1, breast cancer type 1 susceptibility protein, Breast cancer type 1 susceptibility protein homolog, BROVCA1, BROVCA12, Delta772-3095, early onset breast cancer 1, Fanconi anemia, complementation group S, FANCS, IRIS, OTTHUMP00000212147, OTTHUMP00000212148, OTTHUMP00000212149, OTTHUMP00000212150, OTTHUMP00000212151, OTTHUMP00000212155, PNCA4, PPP1R53, protein phosphatase 1, regulatory subunit 53, PSCP, RING finger protein 53, RING-type E3 ubiquitin transferase BRCA1, RNF53, truncated BRCA1, truncated breast and ovarian cancer susceptibility protein 1, truncated breast and ovarian cancer sususceptibility protein 1, truncated breast cancer type 1 susceptibility protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12189, 497672, 672
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.81 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O54952, P38398, P48754
Gene Symbols:
BRCA1
Immunogen:
A synthetic phosphorylated peptide around S1423 of human BRCA1 (NP_0092251)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-ERK1 (Tyr204)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAPK3
Gene Alias: ERK, Erk1, ERK-1, Ert2, Esrk1, Extracellular signal-regulated kinase 1, extracellular signal-related kinase 1, HS44KDAP, HUMKER1A, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAP kinase 3, MAP kinase isoform p44, MAP kinase2, MAPK 1, MAPK 3, MAPK1, MAPK2, MAPK3, Microtubule-associated protein 2 kinase, mitogen activated protein kinase 3, mitogen-activated 3, mitogen-activated protein kinase 1, mitogen-activated protein kinase 3, MNK1, Mtap2k, p44, p44 MAP kinase, P44ERK1, p44-ERK1, P44MAPK, p44-MAPK, pp42/MAP kinase, PRKM3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26417, 50689, 5595
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1.84 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P21708, P27361, Q63844
Gene Symbols: MAPK3
Immunogen: A synthetic phosphorylated peptide around Y204 of human ERK1 (NP_0027372)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ERK1 (Tyr204)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAPK3
Gene Alias:
ERK, Erk1, ERK-1, Ert2, Esrk1, Extracellular signal-regulated kinase 1, extracellular signal-related kinase 1, HS44KDAP, HUMKER1A, Insulin-stimulated MAP2 kinase, MAP kinase 1, MAP kinase 3, MAP kinase isoform p44, MAP kinase2, MAPK 1, MAPK 3, MAPK1, MAPK2, MAPK3, Microtubule-associated protein 2 kinase, mitogen activated protein kinase 3, mitogen-activated 3, mitogen-activated protein kinase 1, mitogen-activated protein kinase 3, MNK1, Mtap2k, p44, p44 MAP kinase, P44ERK1, p44-ERK1, P44MAPK, p44-MAPK, pp42/MAP kinase, PRKM3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26417, 50689, 5595
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1.84 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P21708, P27361, Q63844
Gene Symbols:
MAPK3
Immunogen:
A synthetic phosphorylated peptide around Y204 of human ERK1 (NP_0027372)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-STAT2 (Tyr690)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Stat2
Gene Alias: 1110034C02Rik, 1600010G07Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, Aprf, AW109958, AW496480, DNA-binding protein APRF, EGK_03803, HIES, IMD44, interferon alpha induced transcriptional activator, ISGF-3, MGC59816, p113, signal transducer and activator of transcription 2, signal transducer and activator of transcription 2, 113kDa, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), STAT, STAT 2, STAT113, STAT2, STAT-2, Stat3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20847, 288774, 6773
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.53 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P52630, Q9WVL2
Gene Symbols: Stat2
Immunogen: A synthetic phosphorylated peptide around Y690 of human STAT2 (NP_0054101)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-STAT2 (Tyr690)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Stat2
Gene Alias:
1110034C02Rik, 1600010G07Rik, acute phase response factor, acute-phase response factor, ADMIO, ADMIO1, Aprf, AW109958, AW496480, DNA-binding protein APRF, EGK_03803, HIES, IMD44, interferon alpha induced transcriptional activator, ISGF-3, MGC59816, p113, signal transducer and activator of transcription 2, signal transducer and activator of transcription 2, 113kDa, signal transducer and activator of transcription 3, signal transducer and activator of transcription 3 (acute-phase response factor), STAT, STAT 2, STAT113, STAT2, STAT-2, Stat3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20847, 288774, 6773
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.53 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P52630, Q9WVL2
Gene Symbols:
Stat2
Immunogen:
A synthetic phosphorylated peptide around Y690 of human STAT2 (NP_0054101)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NFkB p65 (Ser311)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RELA
Gene Alias: avian reticuloendotheliosis viral (v-rel) oncogene homolog A, EBP-1, I79_021812, MGC131774, NF KB, NFkappaB p65, nf-kappa-b p65, NF-kappa-B p65delta3, NF-kappa-B transcription factor p65, NF-kappaB transcription factor p65 subunit, NFkB, NF-kB p65 subunit, nfkb rela, NFKB1, nfkb3, NFkB-p50, nuclear factor, nuclear factor kappa b, nuclear factor kappa B subunit p65, nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65, p65 NF kappaB, p65 NF-kappa B, p65 NFkB, P65 transcription factor, putative transcription factor p65 homolog, REL A, rel1, rela, RELA proto-oncogene, NF-kB subunit, rela.L, rela-a, Transcription factor p65, v-rel avian reticuloendotheliosis viral oncogene homolog A, v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog, v-rel reticuloendotheliosis viral oncogene homolog A, v-rel reticuloendotheliosis viral oncogene homolog A (avian), v-rel reticuloendotheliosis viral oncogene homolog A, nuclear fa
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19697, 5970
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.19 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q04206, Q04207
Gene Symbols: RELA
Immunogen: A synthetic phosphorylated peptide around S311 of human RelA (NP_0688103)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NFkB p65 (Ser311)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RELA
Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene homolog A, EBP-1, I79_021812, MGC131774, NF KB, NFkappaB p65, nf-kappa-b p65, NF-kappa-B p65delta3, NF-kappa-B transcription factor p65, NF-kappaB transcription factor p65 subunit, NFkB, NF-kB p65 subunit, nfkb rela, NFKB1, nfkb3, NFkB-p50, nuclear factor, nuclear factor kappa b, nuclear factor kappa B subunit p65, nuclear factor NF-kappa-B p65 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65, p65 NF kappaB, p65 NF-kappa B, p65 NFkB, P65 transcription factor, putative transcription factor p65 homolog, REL A, rel1, rela, RELA proto-oncogene, NF-kB subunit, rela.L, rela-a, Transcription factor p65, v-rel avian reticuloendotheliosis viral oncogene homolog A, v-rel avian reticuloendotheliosis viral oncogene homolog A L homeolog, v-rel reticuloendotheliosis viral oncogene homolog A, v-rel reticuloendotheliosis viral oncogene homolog A (avian), v-rel reticuloendotheliosis viral oncogene homolog A, nuclear fa
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19697, 5970
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.19 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q04206, Q04207
Gene Symbols:
RELA
Immunogen:
A synthetic phosphorylated peptide around S311 of human RelA (NP_0688103)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG