PIPA597379

Phospho-FAK (Tyr925) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597379-Each-of-1 In Stock ₹ 44,705.10

PIPA597379 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-FAK (Tyr925)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTK2

Gene Alias

CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5747

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.41 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

Q05397

Gene Symbols

PTK2

Immunogen

A synthetic phosphorylated peptide around Y925 of human FAK (NP_7225601)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: JK; Cellular Location: Cell junction, Cell membrane, Cytoplasm, Cytoplasmic side, Nucleus, Peripheral membrane protein, cell cortex, centrosome, cytoskeleton, focal adhesion, microtubule organizing center Immunogen sequence: KVYEN Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling
  • FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle
  • FAK has a central catalytic domain and a C-terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors
  • Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin
  • Adhesion of murine NIH3T3 fibroblasts to fibronectin promotes association of the Grb2 adapter protein and c-Src PTK with FAK in vivo, and also results in activation of the ERK2 MAP kinase
  • In v-Src-transformed NIH3T3, the association of v-Src, Grb2, and Sos with FAK is independent of cell adhesion to fibronectin
  • In vitro the Grb2 SH2 domain binds directly to tyrosine-phosphorylated FAK, and the binding site has been identified as Tyr925 by site directed mutagenesis
  • Several transcript variants encoding different isoforms have been found for the FAK gene, but the full-length natures of only three of them have been determined.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA597379

--


Antigen:
Phospho-FAK (Tyr925)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTK2

Gene Alias:
CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5747

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.41 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q05397

Gene Symbols:
PTK2

Immunogen:
A synthetic phosphorylated peptide around Y925 of human FAK (NP_7225601)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA597380

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Antigen:
Phospho-LKB1 (Ser428)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STK11

Gene Alias:
AA408040, CAMK group, CAMKL family, hLKB1, liver kinase B1, Liver kinase B1 homolog, LKB 1, LKB1, LKB-1, LKB1(S), Par-4, PJS, polarization-related protein LKB1, R75140, renal carcinoma antigen NY-REN-19, serine/threonine kinase 11, serine/threonine-protein kinase 11, serine/threonine-protein kinase LKB1, serine/threonine-protein kinase STK11, STK11

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20869, 314621, 6794

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.34 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
D4AE59, Q15831, Q9WTK7

Gene Symbols:
STK11

Immunogen:
A synthetic phosphorylated peptide around S428 of human STK11 (NP_0004461)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA597381

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Antigen:
Phospho-LKB1 (Thr189)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
STK11

Gene Alias:
AA408040, CAMK group, CAMKL family, hLKB1, liver kinase B1, Liver kinase B1 homolog, LKB 1, LKB1, LKB-1, LKB1(S), Par-4, PJS, polarization-related protein LKB1, R75140, renal carcinoma antigen NY-REN-19, serine/threonine kinase 11, serine/threonine-protein kinase 11, serine/threonine-protein kinase LKB1, serine/threonine-protein kinase STK11, STK11

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20869, 314621, 6794

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.37 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
D4AE59, Q15831, Q9WTK7

Gene Symbols:
STK11

Immunogen:
A synthetic phosphorylated peptide around T189 of human STK11 (NP_0004461)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA597382

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Antigen:
Phospho-PYK2 (Tyr402)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTK2B

Gene Alias:
CADTK, CAK beta, CAKB, CAKbeta, CAK-beta, calcium-dependent tyrosine kinase, Calcium-regulated non-receptor proline-rich tyrosine kinase, cell adhesion kinase beta, cellular adhesion kinase beta, E430023O05Rik, FADK, FADK 2, FADK2, FAK, FAK1, FAK2, focal adhesion kinase 2, FRNK, PKB, pp125FAK, proline-rich tyrosine kinase 2, protein kinase B, protein tyrosine kinase 2 beta, protein-tyrosine kinase 2-beta, PTK, PTK2 protein tyrosine kinase 2 beta, PTK2B, PTK2B protein tyrosine kinase 2 beta, PYK2, RAFTK, related adhesion focal tyrosine kinase

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2185

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.52 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
Q14289

Gene Symbols:
PTK2B

Immunogen:
A synthetic phosphorylated peptide around Y402 of human Pyk2 (NP_0040943)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG