PIPA597409

Phospho-PTPRA (Tyr789) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597409-Each-of-1 In Stock ₹ 44,705.10

PIPA597409 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-PTPRA (Tyr789)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ptpra

Gene Alias

HEPTP, HLPR, Hptp alpha, HPTPA, HPTPalpha, LCA-related phosphatase, Leukocyte common antigen-related peptide (protein tyrosine phosphate), Lrp, protein tyrosine phosphatase alpha, protein tyrosine phosphatase, receptor type A, protein tyrosine phosphatase, receptor type, A, protein tyrosine phosphatase, receptor type, alpha polypeptide, protein-tyrosine phosphatase alpha, PTP alpha, Ptpa, Ptpalpha, PTPase-alpha, PTPLCA-related phosphatase, PTPRA, PTPRL2, PTPTY-28, Receptor-type tyrosine-protein phosphatase alpha, RPTP alpha, RPTPA, Rptpalpha, R-PTP-alpha, Rptra, Rptralpha, tyrosine phosphatase alpha

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19262, 25167, 5786

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Western Blot

Concentration

0.01 mg/mL

Formulation

PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.

P18052, P18433, Q03348

Gene Symbols

Ptpra

Immunogen

A synthetic phosphorylated peptide around Y789 of human PTPRA (NP_5430301)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Positive Samples: C2C12, PC-12; Cellular Location: Membrane, Single-pass type I membrane protein Immunogen sequence: SDYAN Phosphorylation of receptors by protein kinases is a process that can be reversed by a group of enzymes called protein phosphatases
  • Coordinated control of kinases and phosphatases provides the cell with the capacity to rapidly switch between phosphorylated and dephosphorylated protein states in dynamic response to environmental stimuli
  • Activation of critical enzymes by kinase phosphorylation alone is not enough to provide adequate regulation - it is the combination with phosphatase dephosphorylation that effectively creates on/off switches to control cellular events
  • Errors in control, either through kinases or their counterpart phosphatases, can lead to unchecked cell growth attributable to human cancers and developmental disorders
  • Potential mechanisms to control dephosphorylation include changes in the expression of protein phosphatases, their subcellular localization, phosphorylation of phosphatase catalytic and regulatory subunits and regulation by endogenous phosphatase inhibitors
  • Most protein phosphatases are not stringently specific for their substrates
  • Consequently, changes in phosphatase activity may have a broad impact on dephosphorylation and turnover of phosphoproteins that are substrates for different kinases
  • This may be an important point of control to connect cellular circuitry of interrelated signaling pathways, and to synchronize physiological responses.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA597409

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Antigen:
Phospho-PTPRA (Tyr789)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptpra

Gene Alias:
HEPTP, HLPR, Hptp alpha, HPTPA, HPTPalpha, LCA-related phosphatase, Leukocyte common antigen-related peptide (protein tyrosine phosphate), Lrp, protein tyrosine phosphatase alpha, protein tyrosine phosphatase, receptor type A, protein tyrosine phosphatase, receptor type, A, protein tyrosine phosphatase, receptor type, alpha polypeptide, protein-tyrosine phosphatase alpha, PTP alpha, Ptpa, Ptpalpha, PTPase-alpha, PTPLCA-related phosphatase, PTPRA, PTPRL2, PTPTY-28, Receptor-type tyrosine-protein phosphatase alpha, RPTP alpha, RPTPA, Rptpalpha, R-PTP-alpha, Rptra, Rptralpha, tyrosine phosphatase alpha

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19262, 25167, 5786

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.01 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P18052, P18433, Q03348

Gene Symbols:
Ptpra

Immunogen:
A synthetic phosphorylated peptide around Y789 of human PTPRA (NP_5430301)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597411

--


Antigen:
Phospho-SLP76 (Tyr145)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LCP2

Gene Alias:
76 kDa tyrosine phosphoprotein, AI323664, BB161688, Lcp2, Lymphocyte cytosolic protein 2, lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa), lymphocyte cytosolic protein 2 (SH2 domain-containing leukocyte protein of 76kD), SH2 domain-containing leukocyte protein of 76 kDa, SH2 domain-containing leukocyte protein of 76kD, SLP76, SLP-76, SLP-76 tyrosine phosphoprotein, twm

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16822, 3937

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
2.58 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
Q13094, Q60787

Gene Symbols:
LCP2

Immunogen:
A synthetic phosphorylated peptide around Y145 of human LCP2 (NP_0055561)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597413

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Antigen:
Phospho-EGFR (Tyr1045)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EGFR

Gene Alias:
2.7.10.1, 9030024J15Rik, AI552599, avian erythroblastic leukemia viral (v-erbB) oncogene homolog, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10.1, egf receptor, Egfr, EGFR-related peptide, epidermal growth factor receptor, epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian), Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1), epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1), ERBB, ERBB1, ErbB-1, erb-b2 receptor tyrosine kinase 1, Errb1, Errp, HER1, kinase EGFR, mENA, NISBD2, Oncogene ERBB, PIG61, Proto-oncogene c-ErbB-1, receptor tyrosine-protein kinase erbB-1, Urogastrone, wa2, wa-2, Wa5, waved 2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1956

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.16 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P00533

Gene Symbols:
EGFR

Immunogen:
A synthetic phosphorylated peptide around Y1045 of human EGFR (NP_0052192)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597414

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Antigen:
Phospho-AP2M1 (Thr156)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AP2M1

Gene Alias:
adapter-related protein complex 2 mu subunit, adapter-related protein complex 2 subunit mu, adaptin-mu2, Adaptor protein complex AP-2 subunit mu, adaptor related protein complex 2 mu 1 subunit, adaptor related protein complex 2 subunit mu 1, adaptor related protein complex 2, mu 1 subunit, adaptor-related protein complex 2 subunit mu, adaptor-related protein complex 2, mu 1 subunit, AP-2 complex subunit mu, AP-2 mu 2 chain, AP-2 mu chain, Ap2m1, AP50, Clapm1, clathrin adaptor complex AP2, mu subunit, Clathrin assembly protein complex 2 medium chain, clathrin assembly protein complex 2 mu medium chain, clathrin coat adaptor protein AP50, Clathrin coat assembly protein AP50, Clathrin coat-associated protein AP50, clathrin-associated/assembly/adaptor protein, medium 1, coat assembly protein complex 50 kD, HA2 50 kDA subunit, KIAA0109, mu2, Mu2-adaptin, Plasma membrane adaptor AP-2 50 kDa protein, plasma membrane adaptor AP-2 50kDA protein, QtsA-16673, unnamed protein product

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1173, 11773

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
0.34 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P84091, Q96CW1

Gene Symbols:
AP2M1

Immunogen:
A synthetic phosphorylated peptide around T156 of human AP2M1 (NP_0010203761)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG