PIPA597474
ASAH2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597474-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA597474 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ASAH2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Asah2
Gene Alias
acylsphingosine deacylase 2, AI585898, Asah2, BCDase, hCD, HNAC1, LCDase, mitochondrial ceramidase, N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2, N-acylsphingosine amidohydrolase 2, NCDase, N-CDase, Neutral ceramidase, Neutral ceramidase soluble form, neutral/alkaline ceramidase, non-lysosomal ceramidase
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
114104, 56624
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
4 mg/mL
Formulation
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.
Q91XT9, Q9NR71
Gene Symbols
Asah2
Immunogen
Recombinant Human Neutral ceramidase protein (255-506AA)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Sphingolipids are hydrolyzed by ceramidases to yield sphingosine and fatty acids
- These ceramidases are classified according to the pH range that supports their optimal activity
- ASAH2 is a neutral ceramidase and key regulator of sphingolipid signaling metabolites at the cell surface, catalyzing the hydrolysis of the N-acyl linkage of ceramide at an optimal pH of 6.5-8.5
- ASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine
- Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger
- ASAH2 is ubiquitously expressed primarily expressed with higher levels in the intestine, kidney, skeletal muscle and heart
- Recent studies indicate that ASAH2 encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract.
Compare Similar Items
Show Difference
Antigen: ASAH2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Asah2
Gene Alias: acylsphingosine deacylase 2, AI585898, Asah2, BCDase, hCD, HNAC1, LCDase, mitochondrial ceramidase, N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2, N-acylsphingosine amidohydrolase 2, NCDase, N-CDase, Neutral ceramidase, Neutral ceramidase soluble form, neutral/alkaline ceramidase, non-lysosomal ceramidase
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 114104, 56624
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 4 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.: Q91XT9, Q9NR71
Gene Symbols: Asah2
Immunogen: Recombinant Human Neutral ceramidase protein (255-506AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ASAH2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Asah2
Gene Alias:
acylsphingosine deacylase 2, AI585898, Asah2, BCDase, hCD, HNAC1, LCDase, mitochondrial ceramidase, N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2, N-acylsphingosine amidohydrolase 2, NCDase, N-CDase, Neutral ceramidase, Neutral ceramidase soluble form, neutral/alkaline ceramidase, non-lysosomal ceramidase
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
114104, 56624
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
4 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.:
Q91XT9, Q9NR71
Gene Symbols:
Asah2
Immunogen:
Recombinant Human Neutral ceramidase protein (255-506AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ASTN2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ASTN2
Gene Alias: 1d8, Astn2, Astnl, astrotactin 2, astrotactin 2-like, astrotactin-2, bA264C15.1, bA67K19.1, bM243L4.1 (astrotactin 2), bM264P11.1 (astrotactin 2), bM383P24.1 (astrotactin 2), bM423P8.1 (astrotactin 2), bM452J22.1, bM452J22.1 (novel protein), bM468K2.1 (astrotactin 2), Kiaa0634
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 23245
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 5 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.: O75129
Gene Symbols: ASTN2
Immunogen: Recombinant Human Astrotactin-2 protein (108-272AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ASTN2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ASTN2
Gene Alias:
1d8, Astn2, Astnl, astrotactin 2, astrotactin 2-like, astrotactin-2, bA264C15.1, bA67K19.1, bM243L4.1 (astrotactin 2), bM264P11.1 (astrotactin 2), bM383P24.1 (astrotactin 2), bM423P8.1 (astrotactin 2), bM452J22.1, bM452J22.1 (novel protein), bM468K2.1 (astrotactin 2), Kiaa0634
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
23245
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
5 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.:
O75129
Gene Symbols:
ASTN2
Immunogen:
Recombinant Human Astrotactin-2 protein (108-272AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ATG7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATG7
Gene Alias: 1810013K23Rik, Agp7, APG7L, APG7-LIKE, ATG12-activating enzyme E1 ATG7, Atg7, ATG7 autophagy related 7 homolog, Atg7l, autophagy related 7, autophagy related 7 homolog, autophagy-related 7, autophagy-related protein 7, DKFZp434N0735, Gm21553, GSA7, hAGP7, ubiquitin-activating enzyme E1-like protein, Ubiquitin-like modifier-activating enzyme ATG7
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 10533
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 3.5 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.: O95352
Gene Symbols: ATG7
Immunogen: Recombinant Human Ubiquitin-like modifier-activating enzyme ATG7 protein (386-676AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ATG7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATG7
Gene Alias:
1810013K23Rik, Agp7, APG7L, APG7-LIKE, ATG12-activating enzyme E1 ATG7, Atg7, ATG7 autophagy related 7 homolog, Atg7l, autophagy related 7, autophagy related 7 homolog, autophagy-related 7, autophagy-related protein 7, DKFZp434N0735, Gm21553, GSA7, hAGP7, ubiquitin-activating enzyme E1-like protein, Ubiquitin-like modifier-activating enzyme ATG7
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
10533
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
3.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.:
O95352
Gene Symbols:
ATG7
Immunogen:
Recombinant Human Ubiquitin-like modifier-activating enzyme ATG7 protein (386-676AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: ATOH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Atoh1
Gene Alias: ATH1, Atoh1, atonal bHLH transcription factor 1, atonal homolog 1, atonal homolog 1 (Drosophila), atonal homolog bHLH transcription factor 1, BHLHA14, Class A basic helix-loop-helix protein 14, H MATH-1, Hath1, Helix-loop-helix protein hATH-1, helix-loop-helix protein mATH-1, Math1, MATH-1, Protein atonal homolog 1, RGD1565171
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 11921
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 5 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.: P48985
Gene Symbols: Atoh1
Immunogen: Recombinant Mouse Protein atonal homolog 1 protein (1-351AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
ATOH1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Atoh1
Gene Alias:
ATH1, Atoh1, atonal bHLH transcription factor 1, atonal homolog 1, atonal homolog 1 (Drosophila), atonal homolog bHLH transcription factor 1, BHLHA14, Class A basic helix-loop-helix protein 14, H MATH-1, Hath1, Helix-loop-helix protein hATH-1, helix-loop-helix protein mATH-1, Math1, MATH-1, Protein atonal homolog 1, RGD1565171
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
11921
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Western Blot
Concentration:
5 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.:
P48985
Gene Symbols:
Atoh1
Immunogen:
Recombinant Mouse Protein atonal homolog 1 protein (1-351AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG