PIPA597502

BCKDK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597502-Each-of-1 In Stock ₹ 44,705.10

PIPA597502 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

BCKDK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BCKDK

Gene Alias

[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial, AI327402, BCKDHKIN, BCKDK, BCKDKD, BCKD-kinase, BDK, branched chain alpha-ketoacid dehydrogenase kinase, branched chain ketoacid dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase, EC 2.7.11.4

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10295

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.26 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

O14874

Gene Symbols

BCKDK

Immunogen

Recombinant Human [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial protein (153-412AA)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA597501

--

Img

Thermo Scientific

PIPA597248

--

Img

Thermo Scientific

PIPA597427

--

Img

Thermo Scientific

PIPA598011

--

Img

Thermo Scientific

PIPA598423

--

Img

Thermo Scientific

PIPA597660

--

Img

Thermo Scientific

PIPA597439

--

Img

Thermo Scientific

PIPA598588

--

Description

  • The second major step in the catabolism of the branched-chain amino acids, isoleucine, leucine, and valine, is irreversibly catalyzed by the branched-chain alpha-keto acid dehydrogenase complex (BCKD), an inner-mitochondrial enzyme complex composed of 3 catalytic components: a branched-chain alpha-keto acid decarboxylase (E1), a dihydrolipoyl transacylase (E2), and a dihydrolipoamide dehydrogenase (E3)
  • The complex also contains 2 enzymes that regulated the state of activity of the BCKD complex: a kinase (BCKDK), and a phosphorylase
  • The ubiquitously expressed kinase contains 1 histidine kinase domain
  • Maple syrup urine disease (MSUD) is a pathology secondary to an enzyme defect in the catabolic pathway of leucine, isoleucine, and valine
  • Accumulation of these amino acids and their corresponding keto acids results in encephalopathy and progressive neurodegeneration in infants not treated for MSUD.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA597502

--


Antigen:
BCKDK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCKDK

Gene Alias:
[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial, AI327402, BCKDHKIN, BCKDK, BCKDKD, BCKD-kinase, BDK, branched chain alpha-ketoacid dehydrogenase kinase, branched chain ketoacid dehydrogenase kinase, branched-chain alpha-ketoacid dehydrogenase kinase, EC 2.7.11.4

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10295

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.26 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O14874

Gene Symbols:
BCKDK

Immunogen:
Recombinant Human [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial protein (153-412AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597505

--


Antigen:
Survivin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Birc5

Gene Alias:
AAC-11, AP14, Api4, apoptosis inhibitor 4, Apoptosis inhibitor survivin, baculoviral IAP repeat containing 5, baculoviral IAP repeat-containing 5, baculoviral IAP repeat-containing 5 (survivin), baculoviral IAP repeat-containing protein 5, BIRC 5, BIRC5, EPR 1, EPR-1, Iap4, inhibitor of apoptosis, survivin, survivin variant 3 alpha, survivin40, SVV, TIAP

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11799, 332

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
4 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
O15392, O70201

Gene Symbols:
Birc5

Immunogen:
Recombinant Mouse Baculoviral IAP repeat-containing protein 5 protein (1-140AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597506

--


Antigen:
Flavin reductase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BLVRB

Gene Alias:
Biliverdin reductase B, biliverdin reductase B (flavin reductase (NADPH)), biliverdin-IX beta-reductase, BLVRB, BVRB, BVR-B, epididymis secretory protein Li 10, flavin reductase (NADPH), FLR, FR, GHBP, green heme-binding protein, HEL-S-10, NADPH, NADPH-dependent diaphorase, NADPH-flavin reductase, SDR43U1, short chain dehydrogenase/reductase family 43U, member 1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
645

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.38 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
P30043

Gene Symbols:
BLVRB

Immunogen:
Recombinant Human Flavin reductase (NADPH) protein (2-206AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597508

--


Antigen:
Bisphosphoglycerate mutase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BPGM

Gene Alias:
2,3-bisphosphoglycerate mutase, 2,3-bisphosphoglycerate mutase, erythrocyte, 2,3-bisphosphoglycerate synthase, 2,3-diphosphoglycerate mutase, Ab2-098, AI323730, AL022789, Bisphosphoglycerate mutase, BPG-dependent PGAM, Bpgm, C86192, DPGM, erythrocyte 2,3-bisphosphoglycerate mutase, hypothetical protein LOC533785, testis secretory sperm-binding protein Li 202a, zgc:92230

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12183, 669

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.69 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P07738, P15327

Gene Symbols:
BPGM

Immunogen:
Recombinant Human Bisphosphoglycerate mutase protein (1-259AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG