PIPA597510

BRCC3 Polyclonal Antibody, Invitrogen™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597510-Each-of-1 In Stock ₹ 44,705.10

PIPA597510 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

BRCC3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BRCC3

Gene Alias

6.1A protein, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRCA1/BRCA2-containing complex, subunit 3, BRCA1-A complex subunit BRCC36, Brcc3, BRCC36, BRISC complex subunit BRCC36, C6.1A, CXorf53, lys-63-specific deubiquitinase BRCC36, RP11-143H17.2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

79184

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.38 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

P46736

Gene Symbols

BRCC3

Immunogen

Recombinant Human Lys-63-specific deubiquitinase BRCC36 protein (1-316AA)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Fischer Scientific

PIPA597511

--

Img

Fischer Scientific

PIPA597560

--

Img

Fischer Scientific

PIPA597526

--

Img

Fischer Scientific

PIPA597561

--

Img

Fischer Scientific

PIPA5122149

--

Img

Fischer Scientific

PIPA5122150

--

Img

Fischer Scientific

PIPA599015

--

Img

Fischer Scientific

PIPA5122001

--

Description

  • Together with the breast and ovarian predisposition proteins BRCA1 and BRCA2 and RAD51 and BRCC45, BRCC36 forms a holoenzyme complex that possesses a ubiquitin E3 ligase activity
  • Aberrant levels of BRCC36 were detected in sporadic breast tumors and depletion of either BRCC36 or BRCC45 by siRNA resulted in increased sensitivity to ionizing radiation and defects in the G2/M checkpoint, indicating that BRCC36 acts to enhance cellular survival following DNA damage
  • Recent experiments have shown that BRCC36 is essential for ionizing radiation-induced BRCA1 phosphorylation and nuclear foci formation, suggesting that BRCC36 may be an important target in the treatment of radiation-resistant breast tumors
  • At least two isoforms of BRCC36 are known to exist.

Compare Similar Items

Show Difference

Img

Fischer Scientific

PIPA597510

--


Antigen:
BRCC3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRCC3

Gene Alias:
6.1A protein, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRCA1/BRCA2-containing complex, subunit 3, BRCA1-A complex subunit BRCC36, Brcc3, BRCC36, BRISC complex subunit BRCC36, C6.1A, CXorf53, lys-63-specific deubiquitinase BRCC36, RP11-143H17.2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
79184

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.38 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P46736

Gene Symbols:
BRCC3

Immunogen:
Recombinant Human Lys-63-specific deubiquitinase BRCC36 protein (1-316AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Fischer Scientific

PIPA597511

--


Antigen:
BRCC3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BRCC3

Gene Alias:
6.1A protein, BRCA1/BRCA2-containing complex subunit 3, BRCA1/BRCA2-containing complex subunit 36, BRCA1/BRCA2-containing complex, subunit 3, BRCA1-A complex subunit BRCC36, Brcc3, BRCC36, BRISC complex subunit BRCC36, C6.1A, CXorf53, lys-63-specific deubiquitinase BRCC36, RP11-143H17.2

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
79184

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
P46736

Gene Symbols:
BRCC3

Immunogen:
Recombinant Human Lys-63-specific deubiquitinase BRCC36 protein (14-316AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597512

--


Antigen:
Beta Lactoglobulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAEP

Gene Alias:
beta lactoglobulin C, beta lactoglobulin D, beta-lactoglobulin, Beta-LG, BLG, bLG C, Bos d 5, lactoglobulin, beta, LGB, PAEP, progestagen-associated endometrial protein

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
280838

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
1.1 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
P02754

Gene Symbols:
PAEP

Immunogen:
Bovine milk Beta-lactoglobulin (Native Protein)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597513

--


Antigen:
BTN3A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BTN3A1

Gene Alias:
BT3.1, BTF5, BTN3.1, BTN3A1, butyrophilin, Butyrophilin subfamily 3 member A1, butyrophilin, subfamily 3, member A1, CD277, dJ45P21.3 (butyrophilin, subfamily 3, member A1)

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11119

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
O00481

Gene Symbols:
BTN3A1

Immunogen:
Recombinant Human Butyrophilin subfamily 3 member A1 protein (30-254AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG