PIPA597684

EBI3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597684-Each-of-1 In Stock ₹ 44,705.10

PIPA597684 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

EBI3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

EBI3

Gene Alias

cytokine receptor, EBI3, EBI-3, EBV-induced gene 3 protein, Epstein-Barr virus induced 3, Epstein-Barr virus induced gene 3, Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor), epstein-Barr virus-induced gene 3 protein, Epstein-Barr virus-induced gene 3 protein homolog, IL-27, IL27 subunit, IL-27 subunit beta, IL27B, IL-27B, IL35 subunit, interleukin-27 subunit beta

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

10148

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

3 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.

Q14213

Gene Symbols

EBI3

Immunogen

Recombinant Human Interleukin-27 subunit beta protein (21-227AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • EBI3 (Epstein-Barr virus Induced-3) is a secreted glycoprotein of the hematopoietin receptor family
  • It plays a critical regulatory role in the induction of Th2-type immune responses and the development of Th2-mediated tissue inflammation in vivo, which may be mediated through the control of iNKT cell function
  • EBI3 dimerizes with p28 and p35 subunits of IL-12 to form new proteins IL-27 and IL-35, respectively
  • IL-27 is an early product of activated antigen presenting cell that is produced upon TLR ligation
  • It negatively regulates Th17 cell differentiation
  • EBI3 is widely expressed and its expression in dendritic cell is transcriptionally regulated by TLR signaling via MyD88 and NF-kappaB during innate immune responses preceding cytokine driven Th cell development
  • EBI3 signal inhibits delayed-type hypersensitivity responses by suppressing IL-17 production and inducing IL-10 hyperproduction
  • EBI3 may play a novel role in controlling tumor metastasis via lung CD8+ T cells, and its deficiency is associated with a diminished production of Th2 cytokines which are known to regulate allergic airway inflammation in asthma
  • Targeted deletion of EBI3 protects mice from lung metastasis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA597684

--


Antigen:
EBI3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EBI3

Gene Alias:
cytokine receptor, EBI3, EBI-3, EBV-induced gene 3 protein, Epstein-Barr virus induced 3, Epstein-Barr virus induced gene 3, Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor), epstein-Barr virus-induced gene 3 protein, Epstein-Barr virus-induced gene 3 protein homolog, IL-27, IL27 subunit, IL-27 subunit beta, IL27B, IL-27B, IL35 subunit, interleukin-27 subunit beta

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10148

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
Q14213

Gene Symbols:
EBI3

Immunogen:
Recombinant Human Interleukin-27 subunit beta protein (21-227AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597685

--


Antigen:
ECD

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ECD

Gene Alias:
5730461K03Rik, Ecd, ecdysoneless cell cycle regulator, ecdysoneless homolog, ecdysoneless homolog (Drosophila), GCR2, HSGT1, Human suppressor of GCR two, protein ecdysoneless homolog, protein SGT1, protein SGT1 homolog, SGT1, SGT1 protein, suppressor of GCR2, suppressor of S. cerevisiae gcr2

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11319

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
O95905

Gene Symbols:
ECD

Immunogen:
Recombinant Human Protein ecdysoneless homolog protein (1-300AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597686

--


Antigen:
ECHS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Echs1

Gene Alias:
C80529, ECHS1, ECHS1D, enoyl CoA hydratase, short chain, 1, mitochondrial, enoyl Coenzyme A hydratase, short chain 1, enoyl Coenzyme A hydratase, short chain, 1, mitochondrial, enoyl-CoA hydratase 1, Enoyl-CoA hydratase short chain 1 mitochondrial, enoyl-CoA hydratase, mitochondrial, enoyl-CoA hydratase, short chain 1, Enoyl-CoA hydratase, short chain 1, mitochondrial, enoyl-CoA hydratase, short chain, 1, mitochondrial, mitochondrial short-chain enoyl-coenzyme A hydratase 1, SCEH, short chain enoyl-CoA hydratase, short-chain enoyl-CoA hydratase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1892, 93747

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P30084, Q8BH95

Gene Symbols:
Echs1

Immunogen:
Recombinant Human Enoyl-CoA hydratase, mitochondrial protein (28-290AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597687

--


Antigen:
ECHS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Echs1

Gene Alias:
C80529, ECHS1, ECHS1D, enoyl CoA hydratase, short chain, 1, mitochondrial, enoyl Coenzyme A hydratase, short chain 1, enoyl Coenzyme A hydratase, short chain, 1, mitochondrial, enoyl-CoA hydratase 1, Enoyl-CoA hydratase short chain 1 mitochondrial, enoyl-CoA hydratase, mitochondrial, enoyl-CoA hydratase, short chain 1, Enoyl-CoA hydratase, short chain 1, mitochondrial, enoyl-CoA hydratase, short chain, 1, mitochondrial, mitochondrial short-chain enoyl-coenzyme A hydratase 1, SCEH, short chain enoyl-CoA hydratase, short-chain enoyl-CoA hydratase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
140547, 1892, 93747

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.59 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P14604, P30084, Q8BH95

Gene Symbols:
Echs1

Immunogen:
Recombinant Human Enoyl-CoA hydratase, mitochondrial protein (28-290AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG