PIPA597739

FCHSD2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597739-Each-of-1 In Stock ₹ 44,705.10

PIPA597739 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

FCHSD2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FCHSD2

Gene Alias

Carom, F-BAR and double SH3 domains protein 2, FCH and double SH3 domains 2, FCH and double SH3 domains protein 2, FCHSD2, KIAA0769, nervous wreck homolog, NWK, NWK1, Protein nervous wreck 1, SH3 multiple domains 3, SH3 multiple domains protein 3, SH3MD3

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

9873

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

4 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.

O94868

Gene Symbols

FCHSD2

Immunogen

Recombinant Human F-BAR and double SH3 domains protein 2 protein (1-290AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA598131

--

Img

Thermo Scientific

PIPA597671

--

Img

Thermo Scientific

PIPA597960

--

Img

Thermo Scientific

PIPA598012

--

Img

Thermo Scientific

PIPA597656

--

Img

Thermo Scientific

PIPA597942

--

Img

Thermo Scientific

PIPA597682

--

Img

Thermo Scientific

PIPA597735

--

Description

  • Adapter protein that plays a role in endocytosis via clathrin-coated pits
  • Contributes to the internalization of cell surface receptors, such as integrin ITGB1 and transferrin receptor (PubMed:29887380)
  • Promotes endocytosis of EGFR in cancer cells, and thereby contributes to the down-regulation of EGFR signaling (PubMed:30249660)
  • Recruited to clathrin-coated pits during a mid-to-late stage of assembly, where it is required for normal progress from U-shaped intermediate stage pits to terminal, omega-shaped pits (PubMed:29887380)
  • Binds to membranes enriched in phosphatidylinositol 3,4-bisphosphate or phosphatidylinositol 3,4,5-trisphosphate (PubMed:29887380)
  • When bound to membranes, promotes actin polymerization via its interaction with WAS and/or WASL which leads to the activation of the Arp2/3 complex
  • Does not promote actin polymerisation in the absence of membranes (PubMed:29887380)
  • [UniProt]

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA597739

--


Antigen:
FCHSD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FCHSD2

Gene Alias:
Carom, F-BAR and double SH3 domains protein 2, FCH and double SH3 domains 2, FCH and double SH3 domains protein 2, FCHSD2, KIAA0769, nervous wreck homolog, NWK, NWK1, Protein nervous wreck 1, SH3 multiple domains 3, SH3 multiple domains protein 3, SH3MD3

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
9873

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
O94868

Gene Symbols:
FCHSD2

Immunogen:
Recombinant Human F-BAR and double SH3 domains protein 2 protein (1-290AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597740

--


Antigen:
FDFT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FDFT1

Gene Alias:
DGPT, EGK_18680, ERG9, farnesyl diphosphate farnesyl transferase 1, farnesyl diphosphate farnesyltransferase, farnesyl-diphosphate farnesyltransferase, farnesyl-diphosphate farnesyltransferase 1, FDFT1, FPP:FPP farnesyltransferase, presqualene-di-diphosphate synthase, SQS, Squalene synthase, squalene synthetase, SS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14137, 2222

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.29 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P37268, P53798

Gene Symbols:
FDFT1

Immunogen:
Recombinant Human Squalene synthase protein (1-260AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597741

--


Antigen:
FDFT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FDFT1

Gene Alias:
DGPT, EGK_18680, ERG9, farnesyl diphosphate farnesyl transferase 1, farnesyl diphosphate farnesyltransferase, farnesyl-diphosphate farnesyltransferase, farnesyl-diphosphate farnesyltransferase 1, FDFT1, FPP:FPP farnesyltransferase, presqualene-di-diphosphate synthase, SQS, Squalene synthase, squalene synthetase, SS

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2222

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
P37268

Gene Symbols:
FDFT1

Immunogen:
Recombinant Human Squalene synthase protein (2-417AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597742

--


Antigen:
FDPS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FDPS

Gene Alias:
(2E,6E)-farnesyl diphosphate synthase, 6030492I17Rik, Ac2-125, AI256750, cholesterol-regulated 39 kDa protein, CR 39, dimethylallyltranstransferase, Farnesyl diphosphate synthase, farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase), farnesyl diphosphate synthetase, farnesyl pyrophosphate synthase, farnesyl pyrophosphate synthetase, farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase, Fdps, Fdpsl1, FPP synthase, FPP synthetase, FPPS, FPS, geranyltranstransferase, KIAA1293, mKIAA1293, POROK9, testis-specific farnesyl pyrophosphate synthetase

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2224

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
P14324

Gene Symbols:
FDPS

Immunogen:
Recombinant Human Farnesyl pyrophosphate synthase protein (1-419AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG