PIPA597967

MDMX Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA597967-Each-of-1 In Stock ₹ 44,705.10

PIPA597967 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MDMX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MDM4

Gene Alias

4933417N07Rik, AA414968, AL023055, AU018793, AU021806, C85810, DKFZp781B1423, double minute 4 homolog, double minute 4 protein, double minute 4, human homolog of, p53-binding protein, HDMX, human homolog of, Mdm2-like p53-binding protein, MDM4, Mdm4 p53 binding protein homolog, MDM4 protein variant G, MDM4 protein variant Y, MDM4, p53 regulator, MDM4-related protein 1, Mdmx, MGC132766, MRP1, p53-binding protein Mdm4, Protein Mdm4, protein Mdmx, RP11-430C7.1, transformed mouse 3T3 cell double minute 4

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

17248, 4194

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Western Blot

Concentration

3 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.

O15151, O35618

Gene Symbols

MDM4

Immunogen

Recombinant Human Protein Mdm4 protein (208-306AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • The MDM2 protein is the primary regulator of p53 protein stability
  • MDMX is an MDM2-related protein that inhibits MDM2-mediated degradation of p53 via distinct associations with MDM2
  • The gene that encodes MDMX (also designated MDM4) is a target for amplification in malignant gliomas
  • ARF interacts with MDMX to sequester MDMX within the nucleolus
  • This sequestration of MDMX by ARF results in an increase in p53 transactivation
  • In addition, expression of MDMX can reverse MDM2-targeted degradation of p53 while maintaining suppression of p53 transactivation
  • Like MDM2, MDMX also binds p73 and stabilizes the level of p73
  • Therefore, in striking contrast to p53, the half-life of p73 is increased by binding to MDM2.

Compare Similar Items

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Img

Thermo Scientific

PIPA597967

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Antigen:
MDMX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MDM4

Gene Alias:
4933417N07Rik, AA414968, AL023055, AU018793, AU021806, C85810, DKFZp781B1423, double minute 4 homolog, double minute 4 protein, double minute 4, human homolog of, p53-binding protein, HDMX, human homolog of, Mdm2-like p53-binding protein, MDM4, Mdm4 p53 binding protein homolog, MDM4 protein variant G, MDM4 protein variant Y, MDM4, p53 regulator, MDM4-related protein 1, Mdmx, MGC132766, MRP1, p53-binding protein Mdm4, Protein Mdm4, protein Mdmx, RP11-430C7.1, transformed mouse 3T3 cell double minute 4

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
17248, 4194

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
O15151, O35618

Gene Symbols:
MDM4

Immunogen:
Recombinant Human Protein Mdm4 protein (208-306AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597968

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Antigen:
RKHD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MEX3A

Gene Alias:
2700083E18Rik, Gm411, mex3 homolog A, mex3 homolog A (C. elegans), mex-3 RNA binding family member A, MEX3A, MEX-3A, RGD1564904, ring finger and KH domain containing 4, ring finger and KH domain containing protein, RING finger and KH domain-containing protein 4, RKHD4, RNA-binding protein MEX3A

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
92312

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4.29 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
A1L020

Gene Symbols:
MEX3A

Immunogen:
Recombinant Human RNA-binding protein MEX3A protein (416-466AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597969

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Antigen:
MGST3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MGST3

Gene Alias:
2010012L10Rik, 2010306B17Rik, 2700004G04Rik, AA516734, Glutathione peroxidase MGST3, GST-III, LTC4 synthase MGST3, MGST3, microsomal glutathione S-transferase, microsomal glutathione S-transferase 3, Microsomal glutathione S-transferase III, microsomal GST-3, Microsomal GST-III

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4259

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
O14880

Gene Symbols:
MGST3

Immunogen:
Recombinant Human Microsomal glutathione S-transferase 3 protein (30-70AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA597970

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Antigen:
PSMB2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSMB2

Gene Alias:
AU045357, AW108089, C7-I, D4Wsu33e, HC7-I, Macropain subunit C7-I, multicatalytic endopeptidase complex subunit C7-1, multicatalytic endopeptidase complex subunit C7-I, proteasome (prosome, macropain) subunit, beta type 2, proteasome (prosome, macropain) subunit, beta type, 2, proteasome beta 2 subunit, proteasome component C7-I, proteasome subunit beta 2, proteasome subunit beta type-2, proteasome subunit, beta type, 2, PSMB2, testicular tissue protein Li 152

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
26445, 5690

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.72 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
P49721, Q9R1P3

Gene Symbols:
PSMB2

Immunogen:
Recombinant Human Proteasome subunit beta type-2 protein (1-201AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG