PIPA598206

Tankyrase Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA598206-Each-of-1 In Stock ₹ 44,705.10

PIPA598206 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Tankyrase

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TNKS

Gene Alias

4930554K12Rik, ADP-ribosyltransferase diphtheria toxin-like 5, AI662855, ARTD5, C86528, D130072O21Rik, HGNC:11941, LOW QUALITY PROTEIN: tankyrase-1, mTNKS1, PARP5A, PARP-5a, PARPL, pART5, Poly [ADP-ribose] polymerase 5A, Poly [ADP-ribose] polymerase tankyrase-1, poly [ADP-ribose] polymerase tankyrase-1, tankyrase-1, Protein poly-ADP-ribosyltransferase tankyrase-1, TANK1, tankyrase, tankyrase 1, tankyrase I, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, tankyrase-1, TIN1, TINF1, TNKS, TNKS1, TNKS-1, TRF1-interacting ankyrin-related ADP-ribose polymerase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

8658

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

3.65 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.

O95271

Gene Symbols

TNKS

Immunogen

Recombinant Human Tankyrase-1 protein (35-130AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking (PubMed:10988299, PubMed:11739745, PubMed:16076287, PubMed:19759537, PubMed:21478859, PubMed:22864114, PubMed:23622245, PubMed:25043379)
  • Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation (PARsylation) of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation (PubMed:19759537, PubMed:21478859)
  • Also mediates PARsylation of BLZF1 and CASC3, followed by recruitment of RNF146 and subsequent ubiquitination (PubMed:21478859)
  • Mediates PARsylation of TERF1, thereby contributing to the regulation of telomere length (PubMed:11739745)
  • Involved in centrosome maturation during prometaphase by mediating PARsylation of HEPACAM2/MIKI (PubMed:22864114)
  • May also regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles (PubMed:10988299)
  • May be involved in spindle pole assembly through PARsylation of NUMA1 (PubMed:16076287)
  • Stimulates 26S proteasome activity (PubMed:23622245)
  • [UniProt]

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Show Difference

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PIPA598206

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Antigen:
Tankyrase

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNKS

Gene Alias:
4930554K12Rik, ADP-ribosyltransferase diphtheria toxin-like 5, AI662855, ARTD5, C86528, D130072O21Rik, HGNC:11941, LOW QUALITY PROTEIN: tankyrase-1, mTNKS1, PARP5A, PARP-5a, PARPL, pART5, Poly [ADP-ribose] polymerase 5A, Poly [ADP-ribose] polymerase tankyrase-1, poly [ADP-ribose] polymerase tankyrase-1, tankyrase-1, Protein poly-ADP-ribosyltransferase tankyrase-1, TANK1, tankyrase, tankyrase 1, tankyrase I, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase, tankyrase-1, TIN1, TINF1, TNKS, TNKS1, TNKS-1, TRF1-interacting ankyrin-related ADP-ribose polymerase, TRF1-interacting ankyrin-related ADP-ribose polymerase 1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
8658

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.65 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
O95271

Gene Symbols:
TNKS

Immunogen:
Recombinant Human Tankyrase-1 protein (35-130AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598211

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Antigen:
p73

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TP73

Gene Alias:
deltaNp73, OTTHUMP00000003479, OTTHUMP00000003480, p53-like transcription factor, p53-related protein, P73, RP23-254N4.10, TAp73, Tp73, transformation related protein 73, Trp73, Tumor protein p73

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7161

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.17 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
O15350

Gene Symbols:
TP73

Immunogen:
Peptide sequence from Human Tumor protein p73 protein (537-555AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598213

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Antigen:
TREM2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Trem2

Gene Alias:
OTTHUMP00000039771, soluble TREM 2, soluble TREM2, sTREM 2, sTREM2, TREM, Trem2, TREM-2, Trem2a, Trem2b, Trem2c, Triggering receptor expressed on monocytes 2, Triggering receptor expressed on myeloid cells, triggering receptor expressed on myeloid cells 2, triggering receptor expressed on myeloid cells 2a, triggering receptor expressed on myeloid cells 2b, triggering receptor expressed on myeloid cells 2c

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
54209, 83433

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
2.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
Q99NH8, Q9NZC2

Gene Symbols:
Trem2

Immunogen:
Recombinant Mouse Triggering receptor expressed on myeloid cells 2 protein (19-171AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA598214

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Antigen:
RFP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRIM13

Gene Alias:
3110001L12Rik, B-cell chronic lymphocytic leukemia tumor suppressor Leu5, CAR, CLL-associated RING finger, DLEU5, E3 ubiquitin-protein ligase TRIM13, LEU5, Leukemia-associated protein 5, putative tumor suppressor RFP2, Ret finger protein 2, Rfp2, RING finger protein 77, RING-type E3 ubiquitin transferase TRIM13, RNF77, TRIM13, tripartite motif containing 13, tripartite motif protein 13, tripartite motif-containing 13, tripartite motif-containing protein 13, tripartite motif-containing protein 13, E3 ubiquitin-protein ligase TRIM13, Unknown (protein for MGC:134296)

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10206

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.18 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O60858

Gene Symbols:
TRIM13

Immunogen:
Recombinant Human E3 ubiquitin-protein ligase TRIM13 protein (40-310AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG