PIPA598297

CD27 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA598297-Each-of-1 In Stock ₹ 44,705.10

PIPA598297 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CD27

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CD27

Gene Alias

CD antigen 27, CD27, CD27 antigen, CD27 molecule, CD27L receptor, LPFS2, S152, S152. LPFS2, sCD27, soluble CD27, T cell activation antigen S152, T14, T-cell activation antigen CD27, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7, tumor necrosis factor receptor superfamily, member 7

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

500318, 939

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

4 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.

P26842

Gene Symbols

CD27

Immunogen

Recombinant Human CD27 antigen protein (20-191AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • CD27 is a 50 kDa member of the tumor necrosis factor (TNF) receptor superfamily that includes CD40 and CD30
  • The TNF superfamily members are known for the regulation of cell proliferation and death
  • In contrast to the expression of other TNFR/TNF family members, expression of CD27 and its ligand CD70 is predominantly confined to lymphocytes
  • High expression levels of CD27 appear to be dependent on proper ligation of antigen receptors
  • CD70 expression requires additional co-stimulatory and/or pro-inflammatory signals
  • CD27 is expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells
  • Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid
  • Soluble CD27 is an important prognostic marker of acute and chronic B cell malignancies
  • RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70
  • CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor
  • Diseases associated with CD27 dysfunction include Lymphoproliferative Syndrome 2 and Autosomal Recessive Lymphoproliferative Syndrome.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA598297

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Antigen:
CD27

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD27

Gene Alias:
CD antigen 27, CD27, CD27 antigen, CD27 molecule, CD27L receptor, LPFS2, S152, S152. LPFS2, sCD27, soluble CD27, T cell activation antigen S152, T14, T-cell activation antigen CD27, TNFRSF7, TNFSF7, Tp55, Tumor necrosis factor receptor superfamily member 7, tumor necrosis factor receptor superfamily, member 7

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
500318, 939

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
P26842

Gene Symbols:
CD27

Immunogen:
Recombinant Human CD27 antigen protein (20-191AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA598298

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Antigen:
IGFBP-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IGFBP1

Gene Alias:
AFBP, alpha-pregnancy-associated endometrial globulin, amniotic fluid binding protein, Binding protein 25, Binding protein 26, Binding protein 28, binding protein-25, binding protein-26, binding protein-28, growth hormone independent-binding protein, hIGFBP 1, hIGFBP1, hIGFBP-1, IBP 1, IBP1, IBP-1, IGF BP25, IGFBA, IGF-binding protein 1, IGFBP, IGFBP 1, Igfbp1, Igfbp-1, IGF-BP25, Insulin like growth factor binding protein, insulin like growth factor binding protein 1, insulin-like growth factor binding protein 1, INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1 PRECURSOR (IGFBP-1) (IBP-1) (IGF-BINDING PROTEIN 1), insulin-like growth factor-binding protein 1, Placental protein 12, PP 12, PP12

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3484

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
P08833

Gene Symbols:
IGFBP1

Immunogen:
Recombinant Human Insulin-like growth factor-binding protein 1 protein (26-259AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598299

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Antigen:
CSNK2A3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CSNK2A3

Gene Alias:
casein kinase 2 alpha 3, casein kinase 2, alpha 1 polypeptide pseudogene, casein kinase 2, alpha 1 polypeptide-like, casein kinase 2, alpha 3 polypeptide, Casein kinase II alpha 1 polypeptide pseudogene, Casein kinase II subunit alpha 3, CK II alpha 3, CSNK2A1P, CSNK2A3

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
283106

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
4.51 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
Q8NEV1

Gene Symbols:
CSNK2A3

Immunogen:
Recombinant Human Casein kinase II subunit alpha 3 protein (151-391AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598300

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Antigen:
PLA2G7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLA2G7

Gene Alias:
1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, Group-VIIA phospholipase A2, gVIIA-PLA2, LDL-associated phospholipase A2, LDL-PLA(2), LDL-PLA2, lipoprotein-associated phospholipase A2, LP-PLA2, PAF 2-acylhydrolase, PAF acetylhydrolase, PAFAD, Pafah, phospholipase A2 group VII, phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma), PLA2G7, Platelet-activating factor acetylhydrolase, R75400

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
7941

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
Q13093

Gene Symbols:
PLA2G7

Immunogen:
Recombinant Human Platelet-activating factor acetylhydrolase protein (49-441AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG