PIPA598351

HLA-DRB3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA598351-Each-of-1 In Stock ₹ 44,705.10

PIPA598351 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

HLA-DRB3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

HLA-DRB3

Gene Alias

DR7, DRB1, DRw10, HLA class II histocompatibility antigen, DR beta 3 chain, HLA class II histocompatibility antigen, DRB1-7 beta chain, HLA DR3B, HLA-DR1B, HLA-DR3B, HLA-DRB, HLA-DRB3, human leucocyte antigen DRB3, major histocompatibility complex, class II, DR beta 3, MGC117330, MHC Class II antigen, MHC class II antigen DR beta 3 chain, MHC class II antigen DRB3, MHC class II HLA-DR beta 3 chain, SS1

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3125

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunocytochemistry, Western Blot

Concentration

3.5 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.

P79483

Gene Symbols

HLA-DRB3

Immunogen

Recombinant Human HLA class II histocompatibility antigen, DR beta 3 chain protein (111-227AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Major histocompatibility complex (MHC) class II molecules destined for presentation to CD4+ helper T cells is determined by two key events
  • These events include the dissociation of class II-associated invariant chain peptides (CLIP) from an antigen binding groove in mhc ii-a/b dimers through the activity of MHC molecules HLA-DM and -DO, and subsequent peptide antigen binding
  • Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM, -DO molecules regulate the dissociation of CLIP and the subsequent binding of exogenous peptides to HLA class II molecules (HLA-DR, -DQ and -DP) by sustaining a conformation that favors peptide exchange
  • RFLP analysis of HLA-DM genes from rheumatoid arthritis (RA) patients suggests that certain polymorphisms are genetic factors for RA susceptibility
  • HLA-B belongs to the HLA class I heavy chain paralogs
  • Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen
  • HLA-B and -C can form heterodimers consisting of a membrane anchored heavy chain and a light chain ( beta-2-Microglobulin)
  • Polymorphisms yield hundreds of HLA-B and -C alleles
  • HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA598351

--


Antigen:
HLA-DRB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HLA-DRB3

Gene Alias:
DR7, DRB1, DRw10, HLA class II histocompatibility antigen, DR beta 3 chain, HLA class II histocompatibility antigen, DRB1-7 beta chain, HLA DR3B, HLA-DR1B, HLA-DR3B, HLA-DRB, HLA-DRB3, human leucocyte antigen DRB3, major histocompatibility complex, class II, DR beta 3, MGC117330, MHC Class II antigen, MHC class II antigen DR beta 3 chain, MHC class II antigen DRB3, MHC class II HLA-DR beta 3 chain, SS1

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3125

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Western Blot

Concentration:
3.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
P79483

Gene Symbols:
HLA-DRB3

Immunogen:
Recombinant Human HLA class II histocompatibility antigen, DR beta 3 chain protein (111-227AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA598352

--


Antigen:
Ribosome-inactivating protein

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
cucurmosin, Ribosome-inactivating protein cucurmosin, rRNA N-glycosidase

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Recombinant Cucurbita moschata Ribosome-inactivating protein cucurmosin protein (1-244AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Plant

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA598353

--


Antigen:
GNAS

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GNAS

Gene Alias:
5530400H20Rik, A930027G11Rik, Adenylate cyclase-stimulating G alpha protein, AHO, ALEX, GNAS, NESP55, alpha-stimulatory subunit of GTP-binding protein, alternative gene product encoded by XL-exon, C130027O20Rik, C20orf45, dJ309F20.1.1, dJ806M20.3.3, Extra large alphas protein, G protein alpha subunit, G protein subunit alpha S, GAIPIRRH peptide, G-alpha-8, Galphas, Gnas, GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus, gnas {ECO:0000312, GNAS complex locus, GNAS complex locus, SCG6 (secretogranin VI), GNAS1, Gnasxl, Gnpas, GPIPIRRH peptide, GPSA, Gs alpha subunit, GSA, G-SALPHA60A, GSP, GTP-binding regulatory protein (G-s-alpha)., GTP-binding regulatory protein alpha subunit exon 1, guanine nucleotide binding protein (G protein), alpha stimulating activity polypeptide 1, guanine nucleotide binding protein alpha s, guanine nucleotide binding protein alpha subunit, guanine nucleotide binding protein, alpha stimulating activity polypeptide 1, guanine nucleotide

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
2778

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3.04 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
O95467, P63092, P84996, Q5JWF2

Gene Symbols:
GNAS

Immunogen:
Recombinant Human Protein ALEX protein (310-404AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA598354

--


Antigen:
AP24

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Recombinant Nicotiana tabacum Osmotin protein (22-246AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Plant

Product Type:
Antibody

Isotype:
IgG