PIPA598392
MST2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA598392-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA598392 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
MST2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
STK3
Gene Alias
0610042I06Rik, KB-1458E12.1, KRS1, Mammalian STE20-like protein kinase 2, mess1, MST, Mst2, MST-2, MST2/C, MST2/N, Mst3, protein kinase homolog, serine/threonine kinase 3, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, Serine/threonine-protein kinase 3 20kDa subunit, Serine/threonine-protein kinase 3 36kDa subunit, Serine/threonine-protein kinase Krs-1, Ste20, STE20-like kinase MST2, STK3, wu:fc19e11, zgc:55383
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
56274, 6788
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
0.66 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q13188, Q9JI10
Gene Symbols
STK3
Immunogen
Recombinant Human Serine/threonine-protein kinase 3 protein (323-450AA)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- STK3 (MST2) is a STE kinase family member that acts upstream of the MAP kinase signaling pathways, and is known to be activated by the proapoptotic stimuli staurosporine and FAS ligand
- STK3 is a stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation
- It is a key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis
- The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ
- Phosphorylation of YAP1 by LATS2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration
- STK3/MST2 and STK4/MST1 are required to repress proliferation of mature hepatocytes, to prevent activation of facultative adult liver stem cells (oval cells), and to inhibit tumor formation.
Compare Similar Items
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Antigen: MST2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STK3
Gene Alias: 0610042I06Rik, KB-1458E12.1, KRS1, Mammalian STE20-like protein kinase 2, mess1, MST, Mst2, MST-2, MST2/C, MST2/N, Mst3, protein kinase homolog, serine/threonine kinase 3, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, Serine/threonine-protein kinase 3 20kDa subunit, Serine/threonine-protein kinase 3 36kDa subunit, Serine/threonine-protein kinase Krs-1, Ste20, STE20-like kinase MST2, STK3, wu:fc19e11, zgc:55383
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56274, 6788
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.66 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q13188, Q9JI10
Gene Symbols: STK3
Immunogen: Recombinant Human Serine/threonine-protein kinase 3 protein (323-450AA)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
MST2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STK3
Gene Alias:
0610042I06Rik, KB-1458E12.1, KRS1, Mammalian STE20-like protein kinase 2, mess1, MST, Mst2, MST-2, MST2/C, MST2/N, Mst3, protein kinase homolog, serine/threonine kinase 3, serine/threonine kinase 3 (STE20 homolog, yeast), serine/threonine kinase 3 (Ste20, yeast homolog), serine/threonine-protein kinase 3, Serine/threonine-protein kinase 3 20kDa subunit, Serine/threonine-protein kinase 3 36kDa subunit, Serine/threonine-protein kinase Krs-1, Ste20, STE20-like kinase MST2, STK3, wu:fc19e11, zgc:55383
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56274, 6788
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.66 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q13188, Q9JI10
Gene Symbols:
STK3
Immunogen:
Recombinant Human Serine/threonine-protein kinase 3 protein (323-450AA)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: BRK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTK6
Gene Alias: ALT-PTK6, breast tumor kinase, BRK, deltam5, FLJ42088, protein tyrosine kinase 6, protein-tyrosine kinase 6, protein-tyrosine kinase BRK, Ptk6, PTK6 protein tyrosine kinase 6, Sik, SRC-related intestinal kinase, tks, Tksk, tyrosine kinase identified from skin, tyrosine-protein kinase BRK
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5753
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Western Blot
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.: Q13882
Gene Symbols: PTK6
Immunogen: Recombinant Human Protein-tyrosine kinase 6 protein (1-113AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
BRK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTK6
Gene Alias:
ALT-PTK6, breast tumor kinase, BRK, deltam5, FLJ42088, protein tyrosine kinase 6, protein-tyrosine kinase 6, protein-tyrosine kinase BRK, Ptk6, PTK6 protein tyrosine kinase 6, Sik, SRC-related intestinal kinase, tks, Tksk, tyrosine kinase identified from skin, tyrosine-protein kinase BRK
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5753
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Western Blot
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.:
Q13882
Gene Symbols:
PTK6
Immunogen:
Recombinant Human Protein-tyrosine kinase 6 protein (1-113AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CUX1/Protein CASP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CUX1
Gene Alias: CASP, CCAAT displacement protein, CDP, CDP/Cut, CDP1, CDP2, Cdpl1, Clox, COY1, cut homolog, cut like homeobox 1, CUTL1, cut-like 1, cut-like homeobox 1, Cux, Cux/CDP, Cux/CDP homeoprotein, Cux1, Cux-1, golgi integral membrane protein 6, GOLIM6, Homeobox protein cut-like 1, homeobox protein cux-1, Kiaa4047, Nbla10317, p100, p110, p200, p75, protein CASP, putative protein product of Nbla10317
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 116639, 13047, 1523
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 3.7 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.: P39880, P53565, P70403, Q13948
Gene Symbols: CUX1
Immunogen: Recombinant Human Protein CASP protein (50-210AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CUX1/Protein CASP
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CUX1
Gene Alias:
CASP, CCAAT displacement protein, CDP, CDP/Cut, CDP1, CDP2, Cdpl1, Clox, COY1, cut homolog, cut like homeobox 1, CUTL1, cut-like 1, cut-like homeobox 1, Cux, Cux/CDP, Cux/CDP homeoprotein, Cux1, Cux-1, golgi integral membrane protein 6, GOLIM6, Homeobox protein cut-like 1, homeobox protein cux-1, Kiaa4047, Nbla10317, p100, p110, p200, p75, protein CASP, putative protein product of Nbla10317
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
116639, 13047, 1523
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
3.7 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.:
P39880, P53565, P70403, Q13948
Gene Symbols:
CUX1
Immunogen:
Recombinant Human Protein CASP protein (50-210AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PSMD6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PSMD6
Gene Alias: 2400006A19Rik, 26S proteasome non-ATPase regulatory subunit 6, 26S proteasome non-ATPase regulatory subunit 6-like protein, 26S proteasome non-ATPase regulatory subunit-like protein, 26S proteasome regulatory subunit RPN7, 26S proteasome regulatory subunit S10, breast cancer-associated protein SGA-113M, KIAA0107, p42A, P44s10, PFAAP4, Phosphonoformate immuno-associated protein 4, proteasome (prosome, macropain) 26S subunit, non-ATPase, 6, proteasome 26S subunit, non-ATPase 6, proteasome regulatory particle subunit p44S10, proteasome, 26S, non-ATPase regulatory subunit 6, PSMD6, Rpn7, S10, SGA-113M, vov, zgc:56471
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 9861
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.08 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.: Q15008
Gene Symbols: PSMD6
Immunogen: Peptide sequence from Human 26S proteasome non-ATPase regulatory subunit 6 protein (355-372AA)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PSMD6
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PSMD6
Gene Alias:
2400006A19Rik, 26S proteasome non-ATPase regulatory subunit 6, 26S proteasome non-ATPase regulatory subunit 6-like protein, 26S proteasome non-ATPase regulatory subunit-like protein, 26S proteasome regulatory subunit RPN7, 26S proteasome regulatory subunit S10, breast cancer-associated protein SGA-113M, KIAA0107, p42A, P44s10, PFAAP4, Phosphonoformate immuno-associated protein 4, proteasome (prosome, macropain) 26S subunit, non-ATPase, 6, proteasome 26S subunit, non-ATPase 6, proteasome regulatory particle subunit p44S10, proteasome, 26S, non-ATPase regulatory subunit 6, PSMD6, Rpn7, S10, SGA-113M, vov, zgc:56471
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
9861
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.08 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.:
Q15008
Gene Symbols:
PSMD6
Immunogen:
Peptide sequence from Human 26S proteasome non-ATPase regulatory subunit 6 protein (355-372AA)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG