PIPA598616

COMMD1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA598616-Each-of-1 In Stock ₹ 44,619.54

PIPA598616 - Each of 1

₹ 44,619.54

In Stock

Quantity

1

Base Price: ₹ 44,619.54

GST (18%): ₹ 8,031.517

Total Price: ₹ 52,651.057

Antigen

COMMD1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

COMMD1

Gene Alias

AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

150684

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1.08 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8N668

Gene Symbols

COMMD1

Immunogen

Recombinant Human COMM domain-containing protein 1 protein (1-190AA)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins
  • Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activiy and dissocoiates CAND1 from CUL1 and CUL2
  • Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation
  • Down-regulates NF-kappa-B activity
  • Involved in the regulation of membrane expression and ubiquitination of SLC12A2
  • Modulates Na(+) transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits and by promoting their ubiquitination presumably involving NEDD4L
  • Promotes the localization of SCNN1D to recycling endosomes
  • Promotes CFTR cell surface expression through regulation of its ubiquitination
  • Down-regulates SOD1 activity by interfering with its homodimerization
  • Plays a role in copper ion homeostasis
  • Involved in copper-dependent ATP7A trafficking between the trans- Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes
  • Can bind one copper ion per monomer
  • May function to facilitate biliary copper excretion within hepatocytes
  • Binds to phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2)
  • Involved in the regulation of HIF1A-mediated transcription; competes with ARNT/Hif-1-beta for binding to HIF1A resulting in decreased DNA binding and impaired transcriptional activation by HIF-1.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA598616

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Antigen:
COMMD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COMMD1

Gene Alias:
AI256843; C2orf5; COMM domain containing 1; COMM domain-containing protein 1; Commd1; copper metabolism (Murr1) domain containing 1; copper metabolism domain containing 1; copper metabolism gene MURR1; Murr1; Protein Murr1; U2/Mu; U2af1-rs1 region 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
150684

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1.08 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q8N668

Gene Symbols:
COMMD1

Immunogen:
Recombinant Human COMM domain-containing protein 1 protein (1-190AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598617

--


Antigen:
TTLL6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TTLL6

Gene Alias:
4932418K24Rik; D11Moh43e; D11Moh44e; polyglutamylase; RGD1311922; t8130b59; TTL.6; TTLL6; Ttll6-ps1; Tubulin polyglutamylase TTLL6; tubulin tyrosine ligase like 6; tubulin tyrosine ligase-like family member 6; tubulin tyrosine ligase-like family, member 6; tubulin tyrosine ligase-like family, member 6, pseudogene 1; tubulin--tyrosine ligase-like protein 6

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
284076

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q8N841

Gene Symbols:
TTLL6

Immunogen:
Recombinant Human Tubulin polyglutamylase TTLL6 protein (121-310AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598618

--


Antigen:
ATP6V0D2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATP6V0D2

Gene Alias:
1620401A02Rik; AI324824; ATP6D2; Atp6v0d2; ATPase H+ transporting V0 subunit d2; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; ATPase, H+ transporting, lysosomal V0 subunit D2; ATPase, H+ transporting, V0 subunit D, isoform 2; FLJ38708; osteoclast-specific vacuolar ATP synthase; similar to ATPase, H+ transporting, V0 subunit D isoform 2; vacuolar proton pump subunit d 2; vacuolar proton-translocating ATPase d subunit d2; V-ATPase; V-ATPase subunit d 2; VMA6; V-type proton ATPase subunit d 2

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
245972

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4.045 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q8N8Y2

Gene Symbols:
ATP6V0D2

Immunogen:
Recombinant Human V-type proton ATPase subunit d 2 protein (50-295AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598620

--


Antigen:
CCDC112

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCDC112

Gene Alias:
8430438M01Rik; AW108467; CCDC112; coiled-coil domain containing 112; coiled-coil domain-containing protein 112; MBC1; mutated in bladder cancer 1; mutated in bladder cancer protein 1; RGD1561942

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
153733

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q8NEF3

Gene Symbols:
CCDC112

Immunogen:
Recombinant Human Coiled-coil domain-containing protein 112 protein (201-446AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG