PIPA598815

MYOC Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA598815-Each-of-1 In Stock ₹ 44,191.74

PIPA598815 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

MYOC

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MYOC

Gene Alias

AI957332; GLC1A; GPOA; JOAG; JOAG1; juvenile-onset open-angle glaucoma 1; mutated trabecular meshwork-induced glucocorticoid response protein; MYOC; Myocilin; Myocilin 20 kDa N-terminal fragment; Myocilin 35 kDa N-terminal fragment; Myocilin 55 kDa subunit; myocilin trabecular meshwork inducible glucocorticoid response; myocilin trabecular meshwork inducible glucocorticoid response protein; Myocilin, C-terminal fragment; Myocilin, N-terminal fragment; myocilin, trabecular meshwork inducible glucocorticoid response; TIGR; trabecular meshwork inducible glucocorticoid response protein; trabecular meshwork-induced glucocorticoid response protein

Host Species

Rabbit

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

4653

Content And Storage

-20°C or -80°C if preferred

Form

Liquid

Applications

ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration

2.61 mg/mL

Formulation

PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.

Q99972

Gene Symbols

MYOC

Immunogen

Recombinant Human Myocilin protein (183-294AA)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Myocilin is an extracellular protein expressed in the eye, including the retina, trabecular meshwork and ciliary body
  • Myocilin can form homomultimers in vivo and can also associate with components of the ECM via interactions with the Hep II domain of FibroPVRL1
  • In addition, myocilin interacts with myosin regulatory light chain, a component of the myosin motor protein complex
  • This interaction implies a role for myocilin in the actomyosin system, linking myocilin to the functional status of the trabecular meshwork (TM), which is responsible for controlling the intraocular pressure (IOP)
  • Alterations in functions of the TM may lead to IOP elevation and development of glaucoma, a major cause of blindness
  • Myocilin is encoded by MYOC (also designated TIGR), a gene that maps to the GLC1A locus on chromosome 1q24
  • 3 and is susceptible to mutations
  • Mutations in the MYOC gene are specifically linked with primary open angle glaucoma (POAG), a blinding disease characterized by progressive loss of retinal ganglion cells.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA598815

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Antigen:
MYOC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYOC

Gene Alias:
AI957332; GLC1A; GPOA; JOAG; JOAG1; juvenile-onset open-angle glaucoma 1; mutated trabecular meshwork-induced glucocorticoid response protein; MYOC; Myocilin; Myocilin 20 kDa N-terminal fragment; Myocilin 35 kDa N-terminal fragment; Myocilin 55 kDa subunit; myocilin trabecular meshwork inducible glucocorticoid response; myocilin trabecular meshwork inducible glucocorticoid response protein; Myocilin, C-terminal fragment; Myocilin, N-terminal fragment; myocilin, trabecular meshwork inducible glucocorticoid response; TIGR; trabecular meshwork inducible glucocorticoid response protein; trabecular meshwork-induced glucocorticoid response protein

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
4653

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
2.61 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q99972

Gene Symbols:
MYOC

Immunogen:
Recombinant Human Myocilin protein (183-294AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598816

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Antigen:
GILZ

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC22D3

Gene Alias:
delta sleep inducing peptide, immunoreactor; delta sleep-inducing peptide immunoreactor; DIP; Dsip1; DSIPI; DSIP-immunoreactive leucine zipper protein; DSIP-immunoreactive peptide; GILZ; glucocorticoid-induced leucine zipper protein; long glucocorticoid-induced leucine zipper protein; Protein DIP; Tilz3; TSC22 domain family 3; TSC22 domain family member 3; TSC22 domain family protein 3; TSC22 domain family, member 3; TSC-22 related protein; TSC22D3; TSC-22-like protein; TSC-22R; TSC22-related inducible leucine zipper 3; TSC-22-related protein; TSC22-related-inducible leucine zipper 3

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1831

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
4.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q99576

Gene Symbols:
TSC22D3

Immunogen:
Recombinant Human TSC22 domain family protein 3 protein (58-134AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA598817

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Antigen:
PITX2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PITX2

Gene Alias:
9430085M16Rik; all1-responsive gene 1; ALL1-responsive protein ARP1; Arp1; Brx1; BRX1 homeoprotein; Brx1b; Homeobox protein PITX2; homeodomain transcription factor 2; IDG2; IGDS; IGDS2; IHG2; IRID2; Munc30; orthodenticle-like homeobox 2; Otlx2; paired like homeodomain 2; paired like homeodomain transcription factor 2; paired-like homeodomain 1; paired-like homeodomain 2; paired-like homeodomain transcription factor 1; paired-like homeodomain transcription factor 2; paired-like homeodomain transcription factor 2c; paired-like homeodomain transcription factor Munc 30; Pituitary homeobox 2; PITX1; Pitx2; Pitx-2; Pitx2c; Ptx2; Rgs; Rieg; RIEG bicoid-related homeobox transcription factor; rieg bicoid-related homeobox transcription factor 1; RIEG1; rPtx2; RS; S a 1 glycoprotein; S a1glycoprotein; S alpha 1 glycoprotein; S a 1 glycoprotein; S a1glycoprotein; Solurshin

Host Species:
Rabbit

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
5308

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4

Gene Accession No.:
Q99697

Gene Symbols:
PITX2

Immunogen:
Recombinant Human Pituitary homeobox 2 protein (40-154AA)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA598819

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Antigen:
NAPG

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NAPG

Gene Alias:
2400003O04Rik; gamma SNAP; GAMMASNAP; gamma-soluble NSF attachment protein; NAPG; N-ethylmaleimide sensitive fusion protein attachment protein gamma; N-ethylmaleimide-sensitive factor attachment protein gamma; N-ethylmaleimide-sensitive factor attachment protein, gamma; NSF attachment protein gamma; SNAPG; SNAP-gamma; SNARE; soluble NSF attachment protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8774

Content And Storage:
-20°C or -80°C if preferred

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.28 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q99747

Gene Symbols:
NAPG

Immunogen:
Recombinant Human Gamma-soluble NSF attachment protein (1-312AA)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG