PIPA598969
LYAR Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA598969-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA598969 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
LYAR
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LYAR
Gene Alias
apoptosis-related protein; cell growth-regulating nucleolar protein; hypothetical protein FLJ20425; Ly1 antibody reactive; Ly1 antibody reactive clone; Ly1 antibody reactive homolog; Ly1 antibody-reactive protein; Lyar; LYAR protein; MLZ-264; PNAS-5; protein expressed in male leptotene and zygotene spermatocytes 264; ZC2HC2; ZLYAR
Host Species
Rabbit
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
55646
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2.5 mg/mL
Formulation
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.
Q9NX58
Gene Symbols
LYAR
Immunogen
Recombinant Human Cell growth-regulating nucleolar protein (1-379AA)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (PubMed:24495227)
- Also acts at the level of transcription regulation
- Along with PRMT5, binds the gamma-globin (HBG1/HBG2) promoter and represses its expression (PubMed:25092918)
- In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and SNORD41 that encodes a small nucleolar RNA (PubMed:28686580)
- Preferentially binds to a DNA motif containing 5'-GGTTAT-3' (PubMed:25092918)
- Negatively regulates the antiviral innate immune response by targeting IRF3 and impairing its DNA-binding activity (PubMed:31413131)
- In addition, inhibits NF-kappa-B-mediated expression of proinflammatory cytokines (PubMed:31413131)
- Stimulates phagocytosis of photoreceptor outer segments by retinal pigment epithelial cells
- Prevents nucleolin/NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal
- [UniProt]
Compare Similar Items
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Antigen: LYAR
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LYAR
Gene Alias: apoptosis-related protein; cell growth-regulating nucleolar protein; hypothetical protein FLJ20425; Ly1 antibody reactive; Ly1 antibody reactive clone; Ly1 antibody reactive homolog; Ly1 antibody-reactive protein; Lyar; LYAR protein; MLZ-264; PNAS-5; protein expressed in male leptotene and zygotene spermatocytes 264; ZC2HC2; ZLYAR
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 55646
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.5 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q9NX58
Gene Symbols: LYAR
Immunogen: Recombinant Human Cell growth-regulating nucleolar protein (1-379AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
LYAR
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LYAR
Gene Alias:
apoptosis-related protein; cell growth-regulating nucleolar protein; hypothetical protein FLJ20425; Ly1 antibody reactive; Ly1 antibody reactive clone; Ly1 antibody reactive homolog; Ly1 antibody-reactive protein; Lyar; LYAR protein; MLZ-264; PNAS-5; protein expressed in male leptotene and zygotene spermatocytes 264; ZC2HC2; ZLYAR
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
55646
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q9NX58
Gene Symbols:
LYAR
Immunogen:
Recombinant Human Cell growth-regulating nucleolar protein (1-379AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CYP39A1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CYP39A1
Gene Alias: 24-hydroxycholesterol 7-alpha-hydroxylase; Cyp39a1; Cytochrome P450 39A1; cytochrome P450 family 39 subfamily A member 1; cytochrome P450, 39a1 (oxysterol 7alpha-hydroxylase); cytochrome P450, family 39, subfamily A, polypeptide 1; cytochrome P450, subfamily XXXIX (oxysterol 7 alpha-hydroxylase), polypeptide 1; hCYP39A1; mCYP39A1; Oxysterol 7-alpha-hydroxylase
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 51302
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 3.09 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q9NYL5
Gene Symbols: CYP39A1
Immunogen: Recombinant Human 24-hydroxycholesterol 7-alpha-hydroxylase protein (235-392AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CYP39A1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CYP39A1
Gene Alias:
24-hydroxycholesterol 7-alpha-hydroxylase; Cyp39a1; Cytochrome P450 39A1; cytochrome P450 family 39 subfamily A member 1; cytochrome P450, 39a1 (oxysterol 7alpha-hydroxylase); cytochrome P450, family 39, subfamily A, polypeptide 1; cytochrome P450, subfamily XXXIX (oxysterol 7 alpha-hydroxylase), polypeptide 1; hCYP39A1; mCYP39A1; Oxysterol 7-alpha-hydroxylase
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
51302
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
3.09 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q9NYL5
Gene Symbols:
CYP39A1
Immunogen:
Recombinant Human 24-hydroxycholesterol 7-alpha-hydroxylase protein (235-392AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: UVRAG
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Uvrag
Gene Alias: 9530039D02Rik; AI648770; BB124205; beclin 1 binding protein; DHTX; disrupted in heterotaxy; hypothetical protein; p63; UV radiation resistance associated; UV radiation resistance associated gene; UV radiation resistance-associated gene protein; UV radiation resistance-associated protein; UVRAG; Uvrag1; Uvragl; VPS38
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 7405
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q9P2Y5
Gene Symbols: Uvrag
Immunogen: Recombinant Human UV radiation resistance-associated gene protein (375-425AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
UVRAG
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Uvrag
Gene Alias:
9530039D02Rik; AI648770; BB124205; beclin 1 binding protein; DHTX; disrupted in heterotaxy; hypothetical protein; p63; UV radiation resistance associated; UV radiation resistance associated gene; UV radiation resistance-associated gene protein; UV radiation resistance-associated protein; UVRAG; Uvrag1; Uvragl; VPS38
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
7405
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q9P2Y5
Gene Symbols:
Uvrag
Immunogen:
Recombinant Human UV radiation resistance-associated gene protein (375-425AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: RBPJL
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RBPJL
Gene Alias: RBP-J kappa-like; RBPJL; RBPL; RBP-L; RBPSUHL; recombination signal binding protein for immunoglobulin kappa J region like; recombination signal binding protein for immunoglobulin kappa J region-like; recombining binding protein suppressor of hairless-like protein; SUHL; Transcription factor RBP-L
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 11317
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.625 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.: Q9UBG7
Gene Symbols: RBPJL
Immunogen: Recombinant Human Recombining binding protein suppressor of hairless-like protein (1-151AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
RBPJL
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RBPJL
Gene Alias:
RBP-J kappa-like; RBPJL; RBPL; RBP-L; RBPSUHL; recombination signal binding protein for immunoglobulin kappa J region like; recombination signal binding protein for immunoglobulin kappa J region-like; recombining binding protein suppressor of hairless-like protein; SUHL; Transcription factor RBP-L
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
11317
Content And Storage:
-20°C or -80°C if preferred
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.625 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Accession No.:
Q9UBG7
Gene Symbols:
RBPJL
Immunogen:
Recombinant Human Recombining binding protein suppressor of hairless-like protein (1-151AA)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG