PIPA599140

Phospho-PAK3 (Ser154) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599140-Each-of-1 In Stock ₹ 44,705.10

PIPA599140 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-PAK3 (Ser154)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PAK3

Gene Alias

2.7.11.1; adriamycin resistance-associated; ARA; beta-PAK; bPAK; CDC42/RAC effector kinase PAK-B; CDKN1A; hPAK3; MRX30; MRX47; oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 3; p21 (RAC1) activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 3; p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related); p21-activated kinase 3; p65-PAK; PAK beta; Pak3; Pak-3; PAK3beta; Pak65alpha; Pak65beta; Pakb; Serine/threonine-protein kinase PAK 3; Stk4

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18481, 29433, 5063

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O75914, Q61036, Q62829

Gene Symbols

PAK3

Immunogen

A synthesized peptide derived from human PAK3(Accession O75914), corresponding to amino acid residues around phosphorylated Ser154.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA599147

--

Img

Thermo Scientific

PIPA599148

--

Img

Thermo Scientific

PIPA599381

--

Img

Thermo Scientific

PIPA596641

--

Img

Thermo Scientific

PIPA599341

--

Img

Thermo Scientific

PIPA599135

--

Img

Thermo Scientific

PIPA599132

--

Img

Thermo Scientific

PIPA599336

--

Description

  • Antibody detects endogenous levels of PAK3 only when phosphorylated at Sersine 154
  • PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling
  • PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities
  • The alpha, beta and gammaPAK isoforms complex specifically with Rac1 and Cdc42 in their active GTP-bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation
  • There are eight sites of autophosphorylation on gammaPAK, including Ser 19, Ser 141 and Thr 402, and phosphorylation of Ser 141 and Thr 402 is correlated with gammaPAK activation
  • Once phosphorylated and their affinity for Rac/Cdc42 reduced, the PAK isoforms disassociate from the complex to seek downstream substrates.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA599140

--


Antigen:
Phospho-PAK3 (Ser154)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PAK3

Gene Alias:
2.7.11.1; adriamycin resistance-associated; ARA; beta-PAK; bPAK; CDC42/RAC effector kinase PAK-B; CDKN1A; hPAK3; MRX30; MRX47; oligophrenin-3; OPHN3; p21 (CDKN1A)-activated kinase 3; p21 (RAC1) activated kinase 3; p21 protein (Cdc42/Rac)-activated kinase 3; p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related); p21-activated kinase 3; p65-PAK; PAK beta; Pak3; Pak-3; PAK3beta; Pak65alpha; Pak65beta; Pakb; Serine/threonine-protein kinase PAK 3; Stk4

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18481, 29433, 5063

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75914, Q61036, Q62829

Gene Symbols:
PAK3

Immunogen:
A synthesized peptide derived from human PAK3(Accession O75914), corresponding to amino acid residues around phosphorylated Ser154.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599141

--


Antigen:
Phospho-C-RAF (Ser301)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Raf1

Gene Alias:
6430402F14Rik; AA990557; BB129353; CMD1NN; CRAF; C-RAF; C-Raf proto-oncogene, serine/threonine kinase; Craf1; Craf1 transforming; D830050J10Rik; EC 2.7.11.1; kinase Raf1; murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV); murine sarcoma 3611 oncogene 1; NS5; Oncogene RAF1; OTTHUMP00000207813; OTTHUMP00000209389; proto-oncogene c-RAF; RAF; raf proto-oncogene serine/threonine protein kinase; RAF proto-oncogene serine/threonine-protein kinase; RAF1; Raf-1; Raf-1 proto-oncogene, serine/threonine kinase; sarcoma 3611 oncogene; v-Raf; v-raf-1 leukemia viral oncogene 1; vraf1 murine le; v-raf-1 murine leukemia viral oncogene homolog 1; v-raf-1 murine leukemia viral oncogene-like protein 1; v-raf-leukemia viral oncogene 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
110157, 24703, 5894

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P04049, P11345, Q99N57

Gene Symbols:
Raf1

Immunogen:
A synthesized peptide derived from human RAF1(Accession P04049), corresponding to amino acid residues around phosphorylated Ser301.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599143

--


Antigen:
Phospho-Dynamin 1 (Ser778)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DNM1

Gene Alias:
AI838169; B-dynamin; D100; Dnm; Dnm1; Dyn1; dynamin 1; Dynamin BREDNM19; dynamin i; dynamin, brain; Dynamin1; Dynamin-1; EC 3.6.5.5; EIEE31; Ftfl; Kiaa4093; mKIAA4093; Neuronal dynamin; OTTHUMP00000215500

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13429, 140694, 1759

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P21575, P39053, Q05193

Gene Symbols:
DNM1

Immunogen:
A synthesized peptide derived from human DNM1(Accession Q05193), corresponding to amino acid residues around phosphorylated Ser778.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599144

--


Antigen:
Phospho-FANCG (Ser383)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FANCG

Gene Alias:
AU041407; DNA repair protein XRCC9; FAG; Fancg; Fanconi anemia complementation group G; Fanconi anemia group G protein; Fanconi anemia group G protein homolog; Fanconi anemia, complementation group G; Protein FACG; truncated Fanconi anemia group G protein; X-ray repair complementing defective repair in Chinese hamster cells 9; X-ray repair, complementing defective, in Chinese hamster, 9; Xrcc9

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2189, 60534, 691105

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O15287, Q9EQR6

Gene Symbols:
FANCG

Immunogen:
A synthesized peptide derived from human FANCG(Accession O15287), corresponding to amino acid residues around phosphorylated Ser383.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG