PIPA599219

PTPN22 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599219-Each-of-1 In Stock ₹ 44,705.10

PIPA599219 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

PTPN22

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ptpn22

Gene Alias

70zpep; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; lymphoid-specific protein tyrosine phosphatase; LyP; LYP1; LYP2; PEP; PEST domain-enriched tyrosine phosphatase; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8; Ptpn22; PTPN8; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 22

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

19260, 26191, 295338

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P29352, Q9Y2R2

Gene Symbols

Ptpn22

Immunogen

A synthesized peptide derived from human PTPN22(Accession Q9Y2R2), corresponding to amino acid residues K770-I807.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total PTPN22
  • The protein tyrosine phosphatase PTPN22 (PTP22, LYP, PEP, formerly PTPN8) is a genetic variant that confers risk of developing diverse human autoimmune diseases such as type 1 diabetes and rheumatoid arthritis
  • The minor allele of a missense SNP in PTPN22 encodes a hematopoietic-specific protein tyrosine phosphatase also known as &quoteLyp.&quote The risk allele is present in about 17% of Caucasian individuals from the general population and in approximately 28% of Caucasian individuals with rheumatoid arthritis; it is thought to disrupt the P1 proline-rich motif that is important for interaction with the Src homology-3 (SH3) domain of CSK (cytoplasmic tyrosine kinase), potentially altering the normal functions of these proteins as negative regulators of T cell activation
  • The interaction between CSK and PTPN22 is highly specific and it is speculated that PTPN22 may be an effector and/or regulator of CSK in T cells and other hematopoietic cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA599219

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Antigen:
PTPN22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ptpn22

Gene Alias:
70zpep; Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP; Lymphoid phosphatase; lymphoid-specific protein tyrosine phosphatase; LyP; LYP1; LYP2; PEP; PEST domain-enriched tyrosine phosphatase; PEST-domain phosphatase; protein tyrosine phosphatase, non-receptor type 22; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); protein tyrosine phosphatase, non-receptor type 8; Ptpn22; PTPN8; tyrosine-phosphatase; Tyrosine-protein phosphatase non-receptor type 22

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19260, 26191, 295338

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P29352, Q9Y2R2

Gene Symbols:
Ptpn22

Immunogen:
A synthesized peptide derived from human PTPN22(Accession Q9Y2R2), corresponding to amino acid residues K770-I807.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599220

--


Antigen:
CIB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CIB3

Gene Alias:
C730014M21Rik; calcium and integrin binding family member 3; calcium and integrin-binding family member 3; CIB3; DNA-dependent protein kinase catalytic subunit-interacting protein 3; Gm1107; Kinase-interacting protein 3; KIP 3; KIP3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
117286, 234421

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q0P523, Q96Q77

Gene Symbols:
CIB3

Immunogen:
A synthesized peptide derived from human CIB3(Accession Q96Q77), corresponding to amino acid residues R137-I187.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599221

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Antigen:
ADNP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Adnp

Gene Alias:
AA589558; activity dependent neuroprotector homeobox; activity-dependent neuroprotective protein; activity-dependent neuroprotector; activity-dependent neuroprotector homeobox; activity-dependent neuroprotector homeobox protein; Adnp; ADNP homeobox 1; ADNP1; HVDAS; KIAA0784; mKIAA0784; MRD28; NAP peptide

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11538, 23394

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9H2P0, Q9Z103

Gene Symbols:
Adnp

Immunogen:
A synthesized peptide derived from human ADNP(Accession Q9H2P0), corresponding to amino acid residues I125-P175.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA599222

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Antigen:
C1orf35

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
C1orf35

Gene Alias:
2310033P09Rik; C1orf35; chromosome 1 open reading frame 35; hMMTAG2; MMTAG2; multiple myeloma transforming 2; multiple myeloma tumor-associated protein 2; Multiple myeloma tumor-associated protein 2 homolog; RGD1304587; RIKEN cDNA 2310033P09 gene; similar to RIKEN cDNA 2310033P09

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
67862, 79169

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q99LX5, Q9BU76

Gene Symbols:
2310033P09Rik, C1orf35

Immunogen:
A synthesized peptide derived from human MMTAG2, corresponding to a region within C-terminal amino acids.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG