PIPA599356
Phospho-BCL-2 (Ser70) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each | PIPA599356-Each | In Stock | ₹ 39,070.97 |
PIPA599356 - Each
In Stock
Quantity
1
Base Price: ₹ 39,070.97
GST (18%): ₹ 7,032.775
Total Price: ₹ 46,103.745
Antigen
Phospho-BCL-2 (Ser70)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Bcl2
Gene Alias
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
12043, 24224, 596
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P10415, P10417, P49950
Gene Symbols
Bcl2
Immunogen
A synthesized peptide derived from human BCL2(Accession P10415), corresponding to amino acid residues around phosphorylated Ser70.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of Bcl-2 only when phosphorylated at Serine 70
- BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
- The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
- Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
- Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
- Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
- Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
- In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
- Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
- The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
Compare Similar Items
Show Difference
Antigen: Phospho-BCL-2 (Ser70)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Bcl2
Gene Alias: apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12043, 24224, 596
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P10415, P10417, P49950
Gene Symbols: Bcl2
Immunogen: A synthesized peptide derived from human BCL2(Accession P10415), corresponding to amino acid residues around phosphorylated Ser70.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-BCL-2 (Ser70)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Bcl2
Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12043, 24224, 596
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P10415, P10417, P49950
Gene Symbols:
Bcl2
Immunogen:
A synthesized peptide derived from human BCL2(Accession P10415), corresponding to amino acid residues around phosphorylated Ser70.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-FGFR1 (Tyr154)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FGFR1
Gene Alias: 2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; basic fibroblast growth factor receptor I; BFGFR; bFGF-R; bFGF-R-1; CD331; CD331 antigen; CEK; CEK1; cek1 protein; cek1 protein precursor; c-fgr; Eask; ECCL; FGF receptor; FGF receptor-1; FGFBR; fgfr 1; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFR1IIIC; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); fibroblast growth factor receptor 1-IIIc; fibroblast growth factor receptor type 1; Flg; FLT2; FLT-2; FMS-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1; MFR; N-sam; OGD; proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14182, 2260, 79114
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P11362, P16092, Q04589
Gene Symbols: FGFR1
Immunogen: A synthesized peptide derived from human FGFR1(Accession P11362), corresponding to amino acid residues around phosphorylated Tyr154.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-FGFR1 (Tyr154)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FGFR1
Gene Alias:
2.7.10.1; AW208770; Basic fibroblast growth factor receptor 1; basic fibroblast growth factor receptor I; BFGFR; bFGF-R; bFGF-R-1; CD331; CD331 antigen; CEK; CEK1; cek1 protein; cek1 protein precursor; c-fgr; Eask; ECCL; FGF receptor; FGF receptor-1; FGFBR; fgfr 1; Fgfr1; FGFR-1; FGFR1/PLAG1 fusion; FGFR1IIIC; FGFRI; Fibroblast growth factor receptor 1; fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome); fibroblast growth factor receptor 1-IIIc; fibroblast growth factor receptor type 1; Flg; FLT2; FLT-2; FMS-like tyrosine kinase 2; fms-related tyrosine kinase 2; HBGFR; heparin-binding growth factor receptor; HH2; HRTFDS; Hspy; hydroxyaryl-protein kinase; KAL2; LOW QUALITY PROTEIN: fibroblast growth factor receptor 1; MFR; N-sam; OGD; proto-oncogene c-Fgr; Tyrosine kinase receptor CEK1
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14182, 2260, 79114
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P11362, P16092, Q04589
Gene Symbols:
FGFR1
Immunogen:
A synthesized peptide derived from human FGFR1(Accession P11362), corresponding to amino acid residues around phosphorylated Tyr154.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-p47phox (Ser359)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ncf1
Gene Alias: 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NADPH oxidase subunit (47 kD); NADPH oxidase subunit (47kDa); Ncf1; NCF-1; NCF1A; NCF-47K; neutrop; neutrophil cytosol factor 1; neutrophil cytosolic factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); neutrophil NADPH oxidase factor 1; Nox organizer 2; NOXO2; nox-organizing protein 2; P47 phox; p47<phox>; p47phox; p47-phox; phagocyte oxidase 47 kDa; SH3 and PX domain-containing protein 1A; SH3PXD1A
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114553, 653361
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: F1M707, P14598
Gene Symbols: Ncf1
Immunogen: A synthesized peptide derived from human NCF1(Accession P14598), corresponding to amino acid residues around phosphorylated Ser359.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-p47phox (Ser359)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ncf1
Gene Alias:
47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NADPH oxidase organizer 2; NADPH oxidase subunit (47 kD); NADPH oxidase subunit (47kDa); Ncf1; NCF-1; NCF1A; NCF-47K; neutrop; neutrophil cytosol factor 1; neutrophil cytosolic factor 1; neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1); neutrophil NADPH oxidase factor 1; Nox organizer 2; NOXO2; nox-organizing protein 2; P47 phox; p47<phox>; p47phox; p47-phox; phagocyte oxidase 47 kDa; SH3 and PX domain-containing protein 1A; SH3PXD1A
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114553, 653361
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
F1M707, P14598
Gene Symbols:
Ncf1
Immunogen:
A synthesized peptide derived from human NCF1(Accession P14598), corresponding to amino acid residues around phosphorylated Ser359.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-GATA1 (Ser142)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Gata1
Gene Alias: eryf1; Erythroid transcription factor; erythroid transcription factor 1; GATA binding protein 1; GATA binding protein 1 (globin transcription factor 1); GATA1; GATA-1; GATA-binding factor 1; GATA-binding protein 1; GATA-binding protein 1 (globin transcription factor 1); GF1; Gf-1; globin transcription factor 1; HGNC:4170; NFE1; NF-E1; NF-E1 DNA-binding protein; nuclear factor, erythroid 1; transcription factor GATA1; XLANP; XLTDA; XLTT
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14460, 25172, 2623
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P15976, P17679, P43429
Gene Symbols: Gata1
Immunogen: A synthesized peptide derived from human GATA1(Accession P15976), corresponding to amino acid residues around phosphorylated Ser142.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-GATA1 (Ser142)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Gata1
Gene Alias:
eryf1; Erythroid transcription factor; erythroid transcription factor 1; GATA binding protein 1; GATA binding protein 1 (globin transcription factor 1); GATA1; GATA-1; GATA-binding factor 1; GATA-binding protein 1; GATA-binding protein 1 (globin transcription factor 1); GF1; Gf-1; globin transcription factor 1; HGNC:4170; NFE1; NF-E1; NF-E1 DNA-binding protein; nuclear factor, erythroid 1; transcription factor GATA1; XLANP; XLTDA; XLTT
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14460, 25172, 2623
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P15976, P17679, P43429
Gene Symbols:
Gata1
Immunogen:
A synthesized peptide derived from human GATA1(Accession P15976), corresponding to amino acid residues around phosphorylated Ser142.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG