PIPA599371

Phospho-SREBP1 (Ser439) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599371-Each-of-1 In Stock ₹ 44,191.74

PIPA599371 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

Phospho-SREBP1 (Ser439)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

SREBF1

Gene Alias

ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; bHLHd1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

20787, 6720, 78968

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P36956, P56720, Q9WTN3

Gene Symbols

SREBF1

Immunogen

A synthesized peptide derived from human SREBF1(Accession P36956), corresponding to amino acid residues around phosphorylated Ser439.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA599361

--

Img

Thermo Scientific

PIPA599233

--

Img

Thermo Scientific

PIPA599323

--

Img

Thermo Scientific

PIPA599137

--

Img

Thermo Scientific

PIPA599265

--

Img

Thermo Scientific

PIPA599470

--

Img

Thermo Scientific

PIPA599320

--

Img

Thermo Scientific

PIPA599188

--

Description

  • Antibody detects endogenous levels of SREBP1 only when phosphorylated at Serine 439
  • Sterol regulatory element-binding proteins (SREBPs) are transcription factors that are members of the basic helix-loop-helix leucine zipper family of DNA binding proteins
  • Three isoforms have been identified in mammalian tissues that vary in structure, regulation, and function
  • SREBP-1a and SREBP-1c (originally cloned as ADD1) are protein products of alternative promoter usage of the SREBP-1 gene
  • The third isoform is transcribed from a different gene, SREBP-2
  • SREBPs are present as 120 kDa inactive precursors in the endoplasmic reticulum (ER) membrane
  • Upon activation, the SREBP protein is translocated to the Golgi and proteolytic cleavage occurs resulting in a mature transcriptionally active 60-78 kDa fragment
  • In liver and adipose tissues, SREBPs have a significant influence on lipid and cholesterol accumulation by inducing the transcription of genes involved in these processes
  • While SREBP-1 is thought to be more important in regulating the expression of genes involved in triglyceride synthesis and accumulation, SREBP-2 has been more closely linked to those involved in cholesterol synthesis and accumulation.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA599371

--


Antigen:
Phospho-SREBP1 (Ser439)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SREBF1

Gene Alias:
ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; bHLHd1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20787, 6720, 78968

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P36956, P56720, Q9WTN3

Gene Symbols:
SREBF1

Immunogen:
A synthesized peptide derived from human SREBF1(Accession P36956), corresponding to amino acid residues around phosphorylated Ser439.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599372

--


Antigen:
Phospho-Alpha-synuclein (Tyr136)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SNCA

Gene Alias:
Alpha synuclein; alphaSYN; alpha-synuclein; NACP; non A-beta component of AD amyloid; non-A beta component of AD amyloid; non-A4 component of amyloid; Non-A4 component of amyloid precursor; PARK1; PARK4; PD1; Snca; Syn; synuclein alpha; synuclein alpha-140; synuclein, alpha; synuclein, alpha (non A4 component of amyloid precursor)

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20617, 29219, 6622

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O55042, P37377, P37840

Gene Symbols:
SNCA

Immunogen:
A synthesized peptide derived from human SNCA(Accession P37840), corresponding to amino acid residues around phosphorylated Tyr136.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599373

--


Antigen:
Phospho-p21 (Thr145)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDKN1A

Gene Alias:
Activating Fragment 1; CAP20; cdk inhibitor CIP1; cdk inhibitor CIP1 (p21); CDKI; CDK-interacting protein 1; CDK-interaction protein 1; Cdkn1; CDKN1A; CDNK1A; CIP1; Cip1); cyclin dependent kinase inhibitor 1A; cyclin-dependent kinase inhibitor 1; cyclin-dependent kinase inhibitor 1A; Cyclin-dependent kinase inhibitor 1A (p21; cyclin-dependent kinase inhibitor 1A (P21); cyclin-dependent kinase inhibitor 1A (p21, Cip1); cyclin-dependent kinase inhibitor 1A variant 1; cyclin-dependent kinase inhibitor 1A variant 2; DNA synthesis inhibitor; MDA6; MDA-6; melanoma differentiation associated protein 6; melanoma differentiation-associated protein; Melanoma differentiation-associated protein 6; OTTHUMP00000016298; p21; p21<WAF1/CIP1>; p21Cip1; p21Cip1/Waf1; p21WAF; PIC1; putative cyclin-dependent kinase inhibitor 1A (p21/WAF1/CIP1); SDI1; SLC12A9; UV96; WAF1; Wild type p53 activated fragment 1 (WAF1); wild-type p53-activated fragment 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1026, 114851, 12575

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P38936, P39689

Gene Symbols:
CDKN1A

Immunogen:
A synthesized peptide derived from human CDKN1A(Accession P38936), corresponding to amino acid residues around phosphorylated Thr145.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599374

--


Antigen:
Phospho-JNK1/JNK2/JNK3 (Thr183)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAPK8

Gene Alias:
AI849689; AI851083; C230008H04Rik; c-Jun kinase 2; c-Jun N-terminal kinase 1; c-Jun N-terminal kinase 2; c-Jun N-terminal kinase 3; FLJ12099; FLJ33785; hypothetical protein LOC569698; janus kinase 1; janus kinase 2; JNK; JNK 46; JNK 55; JNK/SAPK alpha; JNK1; JNK1 beta1 protein kinase; JNK1A2; Jnk2; JNK21B1/2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; Jnk3; JNK3 alpha protein kinase; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3A; JNK3B1; JNK3B2; JNK-46; JNK-55; Jun kinase; JUN N-terminal kinase; MAP kinase 10; MAP kinase 8; MAP kinase 9; MAP kinase p49 3F12; MAPK 10; MAPK 8; MAPK 9; Mapk10; Mapk8; Mapk9; MGC137545 protein; MGC50974; Mi; mitogen activated protein kinase 10; mitogen activated protein kinase 8; mitogen activated protein kinase 9; mitogen-activated protein kinase 10; Mitogen-activated protein kinase 8; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 9; MK10; p493F12; p54 g

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116554, 25272, 26414, 26419, 26420, 50658, 5599, 5601, 5602

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P45983, P45984, P49185, P49186, P49187, P53779, Q61831, Q91Y86, Q9WTU6

Gene Symbols:
MAPK10, MAPK8, MAPK9

Immunogen:
A synthesized peptide derived from human MAPK8(Accession P45983), corresponding to amino acid residues around phosphorylated Thr183.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG