PIPA599466

TrxR2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599466-Each-of-1 In Stock ₹ 44,705.10

PIPA599466 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TrxR2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TXNRD2

Gene Alias

AA118373; ESTM573010; KIAA1652; Selenoprotein Z; SelZ; TGR; thioredoxin reductase 2; thioredoxin reductase 2, mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; thioredoxin reductase TR3; TR; TR beta; TR3; TR-BETA; Trxr2; Trxrd2; TXNRD2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

10587, 26462, 50551

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9JLT4, Q9NNW7, Q9Z0J5

Gene Symbols

TXNRD2

Immunogen

A synthesized peptide derived from human TXNRD2(Accession Q9NNW7), corresponding to amino acid residues M491-V519.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total TXNRD2
  • The mammalian thioredoxin reductases (TrxRs) are a family of selenocysteine-containing pyridine nucleotide-disulfide oxidoreductases
  • All the mammalian TrxRs are homologous to glutathione reductase with respect to primary structure including the conserved redox catalytic site (-Cys-Val-Asn-Val-Gly-Cys-) but distinctively with a C-terminal extension containing a catalytically active penultimate selenocysteine (SeCys) residue in the conserved sequence (-Gly-Cys-SeCys-Gly)
  • TrxR is homodimeric protein in which each monomer includes an FAD prosthetic group, a NADPH binding site and a redox catalytic site
  • Electrons are transferred from NADPH via FAD and the active-site disulfide to C-terminal SeCys-containing redox center, which then reduces the substrate like thioredoxin
  • The members of TrxR family are 55-58 kilodalton in molecular size and composed of three isoforms including cytosolic TrxR1, mitochondrial TrxR2, and TrxR3, known as Trx and GSSG reductase (TGR)
  • TrxR plays a key role in protection of cells against oxidative stress and redox-regulatory mechanism of transcription factors and various biological phenomena.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA599466

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Antigen:
TrxR2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TXNRD2

Gene Alias:
AA118373; ESTM573010; KIAA1652; Selenoprotein Z; SelZ; TGR; thioredoxin reductase 2; thioredoxin reductase 2, mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; thioredoxin reductase TR3; TR; TR beta; TR3; TR-BETA; Trxr2; Trxrd2; TXNRD2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10587, 26462, 50551

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9JLT4, Q9NNW7, Q9Z0J5

Gene Symbols:
TXNRD2

Immunogen:
A synthesized peptide derived from human TXNRD2(Accession Q9NNW7), corresponding to amino acid residues M491-V519.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA599468

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Antigen:
Cyclin C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CCNC

Gene Alias:
AI451004; AU020987; CCNC; CG1C; CycC; cyclin C; cyclin-C; dJ199J3.4 (cyclin C); hSRB11; SRB11 homolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114839, 51813, 892

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P24863, P39947, Q62447

Gene Symbols:
CCNC

Immunogen:
A synthesized peptide derived from human CCNC(Accession P24863), corresponding to amino acid residues E249-S283.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA599469

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Antigen:
hnRNP D

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HNRNPD

Gene Alias:
ARE-binding protein AUFI, type A; Auf1; AUF1A; AU-rich element RNA binding protein 1, 37kDa; AU-rich element RNA-binding factor 1; AU-rich element RNA-binding protein 1; heterogeneous nuclear ribonucleoprotein D; heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa); heterogeneous nuclear ribonucleoprotein D0; hnRNP D0; HNRNPD; hnRNPD0; Hnrpd; P37; RNA binding protein p45AUF1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11991, 3184

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q14103, Q60668

Gene Symbols:
HNRNPD

Immunogen:
A synthesized peptide derived from human HNRNPD(Accession Q14103), corresponding to amino acid residues G59-T109.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA599470

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Antigen:
Phospho-Dematin (Ser403)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DMTN

Gene Alias:
AI325486; dematin; dematin actin binding protein; dematin actin-binding protein; DMT; Dmtn; Epb4.9; Epb49; Erythrocyte membrane protein band 4.9; erythrocyte membrane protein band 4.9 (dematin); erythrocyte protein band 4.9

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13829, 2039

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q08495, Q9WV69

Gene Symbols:
DMTN

Immunogen:
A synthesized peptide derived from human DMTN(Accession Q08495), corresponding to amino acid residues around phosphorylated Ser403.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG