PIPA599550

PKD1/2/3/PKC mu Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA599550-Each-of-1 In Stock ₹ 43,592.82

PIPA599550 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

PKD1/2/3/PKC mu

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PRKD1

Gene Alias

4930557O20Rik; 5730497N19Rik; AI325941; EPK2; HSPC187; nPKC-D1; nPKC-D2; nPKC-mu; nPKC-nu; Pkcm; PKC-MU; Pkcnu; PKC-NU; PKD; PKD1; PKD2; PKD3; Prkcm; Prkcn; Prkd1; PRKD2; Prkd3; Protein kinase C mu type; protein kinase C nu type; protein kinase C, mu; protein kinase C, nu; protein kinase D; protein kinase D1; protein kinase D2; protein kinase D3; protein kinase EPK2; RGD1308054; Serine/threonine-protein kinase D1; serine/threonine-protein kinase D2; Serine/threonine-protein kinase D3

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

101540, 18760, 23683, 25865, 292658, 313834, 5587, 75292, 85421

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O94806, Q15139, Q5XIS9, Q62101, Q8BZ03, Q8K1Y2, Q9BZL6, Q9WTQ1

Gene Symbols

PRKD1, PRKD2, PRKD3

Immunogen

A synthesized peptide derived from human PRKD1(Accession Q15139), corresponding to amino acid residues L714-L764.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total PKD1/2/3/PKC mu
  • Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response
  • Phosphorylates the epidermal growth factor receptor (EGFR) on dual threonine residues, which leads to the suppression of epidermal growth factor (EGF)-induced MAPK8/JNK1 activation and subsequent JUN phosphorylation
  • Phosphorylates RIN1, inducing RIN1 binding to 14-3-3 proteins YWHAB, YWHAE and YWHAZ and increased competition with RAF1 for binding to GTP-bound form of Ras proteins (NRAS, HRAS and KRAS)
  • Acts downstream of the heterotrimeric G-protein beta/gamma-subunit complex to maintain the structural integrity of the Golgi membranes, and is required for protein transport along the secretory pathway
  • In the trans-Golgi network (TGN), regulates the fission of transport vesicles that are on their way to the plasma membrane.

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Img

Thermo Scientific

PIPA599550

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Antigen:
PKD1/2/3/PKC mu

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRKD1

Gene Alias:
4930557O20Rik; 5730497N19Rik; AI325941; EPK2; HSPC187; nPKC-D1; nPKC-D2; nPKC-mu; nPKC-nu; Pkcm; PKC-MU; Pkcnu; PKC-NU; PKD; PKD1; PKD2; PKD3; Prkcm; Prkcn; Prkd1; PRKD2; Prkd3; Protein kinase C mu type; protein kinase C nu type; protein kinase C, mu; protein kinase C, nu; protein kinase D; protein kinase D1; protein kinase D2; protein kinase D3; protein kinase EPK2; RGD1308054; Serine/threonine-protein kinase D1; serine/threonine-protein kinase D2; Serine/threonine-protein kinase D3

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
101540, 18760, 23683, 25865, 292658, 313834, 5587, 75292, 85421

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O94806, Q15139, Q5XIS9, Q62101, Q8BZ03, Q8K1Y2, Q9BZL6, Q9WTQ1

Gene Symbols:
PRKD1, PRKD2, PRKD3

Immunogen:
A synthesized peptide derived from human PRKD1(Accession Q15139), corresponding to amino acid residues L714-L764.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599551

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Antigen:
TRAP220

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MED1

Gene Alias:
Activator-recruited cofactor 205 kDa component; AI480703; ARC205; CRSP1; CRSP200; CRSP210; DRIP205; DRIP230; l11Jus15; MED1; Mediator complex subunit 1; mediator of RNA polymerase II transcription subunit 1; p53 regulatory protein RB18A; Pbp; peroxisome proliferator activated receptor binding protein; peroxisome proliferator-activated receptor-binding protein; Ppar binding protein; PPAR-binding protein; PPARBP; PPARG binding protein; PPARGBP; PPRB; RB18A; RGD1559552; Thyroid hormone receptor-associated protein complex 220 kDa component; thyroid hormone receptor-associated protein complex component TRAP220; thyroid receptor interacting protein 2; thyroid receptor-interacting protein 2; TRAP220; TR-interacting protein 2; TRIP2; TRIP-2; vitamin D receptor-interacting protein 230 kD; vitamin D receptor-interacting protein complex component DRIP205

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19014, 5469

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15648, Q925J9

Gene Symbols:
MED1

Immunogen:
A synthesized peptide derived from human MED1(Accession Q15648), corresponding to amino acid residues Y1431-S1481.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599552

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Antigen:
IkB beta

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NFKBIB

Gene Alias:
I kappa B beta; I(Kappa)B(beta); ikappaBbeta; I-kappa-B-beta; IkB; IKB B; IKB beta; Ikbb; ikB-B; IkBbeta; ikB-beta; NF kappa BIB; NF-kappa-B inhibitor beta; NF-kappa-BIB; NFKB inhibitor beta; NFKBIB; nuclear factor of kappa light chain gene enhancer in B-cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; Thyroid receptor; thyroid receptor-interacting protein 9; TR-interacting protein 9; TRIP 9; TRIP9; TRIP-9

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18036, 4793, 81525

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15653, Q60778, Q9JIA3

Gene Symbols:
NFKBIB

Immunogen:
A synthesized peptide derived from human NFKBIB(Accession Q15653), corresponding to amino acid residues M1-L49.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599554

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Antigen:
DOK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DOK1

Gene Alias:
AW557123; Docking protein 1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); Dok; DOK 1; DOK1; Dok-1; Downstream of tyrosine kinase 1; downstream of tyrosine kinase-1; MGC117395; MGC138860; p240; p62 dok; p62(dok); p62DOK; pp62; TLP1; TP1; TROVE domain family; TROVE1; VAULT2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13448, 1796, 312477

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P97465, Q4QQV2, Q99704

Gene Symbols:
DOK1

Immunogen:
A synthesized peptide derived from human DOK1(Accession Q99704), corresponding to amino acid residues L336-A386.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG