PIPA599647

Kir3.4 (KCNJ5) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599647-Each-of-1 In Stock ₹ 44,705.10

PIPA599647 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Kir3.4 (KCNJ5)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KCNJ5

Gene Alias

cardiac ATP-sensitive potassium channel; cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; GIRK4; GIRK-4; Heart KATP channel; inward rectifier K(+) channel Kir3.4; inward rectifier K+ channel KIR3.4; IRK4; IRK-4; KATP1; KATP-1; KCNJ5; Kir3.4; LQT13; Potassium channel, inwardly rectifying subfamily J member 5; potassium channel, inwardly rectifying subfamily J, member 5; potassium inwardly-rectifying channel, subfamily J, member 5; potassium voltage-gated channel subfamily J member 5

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3762

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P48544

Gene Symbols

KCNJ5

Immunogen

A synthesized peptide derived from human KCNJ5(Accession P48544), corresponding to amino acid residues M1-T37.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total KIR3.4/KCNJ5
  • G protein-coupled inwardly rectifying potassium channels (Kir3.1 through Kir3.4) are coupled to numerous neurotransmitter receptors in the brain and are abundantly expressed in the olfactory bulb, hippocampus, neocortex, dentate gyrus, cerebellar cortex and thalamus regions of the brain
  • Also known as GIRK, Kir3 potassium channels localize to the soma and dendrites as well as axons of neurons
  • Liberated Gbg subunits from G protein heterotrimers bind to and regulate Kir3 channel activity
  • Gb3- and Gb4-containing Gbg dimers bind directly to cytoplasmic domains of Kir3 proteins and increase the K+ current while Gb5-containing Gbg dimers inhibit Kir3 K+ current
  • Kir3 activity is also inhibited by tyrosine phosphorylation
  • Brain-derived neurotrophic factor activates receptor tyrosine kinase B, which then phosphorylates Kir3 tyrosine residues, effectively inactivating the Kir3 channels.

Compare Similar Items

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Img

Thermo Scientific

PIPA599647

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Antigen:
Kir3.4 (KCNJ5)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KCNJ5

Gene Alias:
cardiac ATP-sensitive potassium channel; cardiac inward rectifier; CIR; G protein-activated inward rectifier potassium channel 4; GIRK4; GIRK-4; Heart KATP channel; inward rectifier K(+) channel Kir3.4; inward rectifier K+ channel KIR3.4; IRK4; IRK-4; KATP1; KATP-1; KCNJ5; Kir3.4; LQT13; Potassium channel, inwardly rectifying subfamily J member 5; potassium channel, inwardly rectifying subfamily J, member 5; potassium inwardly-rectifying channel, subfamily J, member 5; potassium voltage-gated channel subfamily J member 5

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3762

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P48544

Gene Symbols:
KCNJ5

Immunogen:
A synthesized peptide derived from human KCNJ5(Accession P48544), corresponding to amino acid residues M1-T37.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599648

--


Antigen:
LONP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LONP2

Gene Alias:
1300002A08Rik; AU015403; HAMAP-Rule:MF_03121}; Lon peptidase 2; lon peptidase 2, peroxisomal; lon protease 2; lon protease 2 {ECO:0000255; Lon protease homolog 2, peroxisomal; lon protease homolog 2, peroxisomal {ECO:0000255; lon protease-like protein 2; lon protease-like protein 2 {ECO:0000255; LONP; Lonp2; LONPL; LRRGT00016; MGC4840; Peroxisomal Lon protease; peroxisomal Lon protease {ECO:0000255; peroxisomal Lon protease homolog 2; peroxisomal LON protease like; Peroxisomal Lon protease-like protein 2-like protein; pLon; RGD1305466

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
83752

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q86WA8

Gene Symbols:
LONP2

Immunogen:
A synthesized peptide derived from human LONP2(Accession Q86WA8), corresponding to amino acid residues R386-N436.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599649

--


Antigen:
LRP10

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
LRP10

Gene Alias:
LDL receptor related protein 10; low-density lipoprotein receptor-related protein 10; LRP10; LRP-10; Lrp9; MST087; MSTP087; SP220; UNQ389/PRO724

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26020, 65107

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q7TQH7, Q7Z4F1

Gene Symbols:
LRP10

Immunogen:
A synthesized peptide derived from human LRP10(Accession Q7Z4F1), corresponding to amino acid residues Q489-G539.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599650

--


Antigen:
ST14

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ST14

Gene Alias:
ARCI11; Epithin; HAI; LOW QUALITY PROTEIN: suppressor of tumorigenicity 14 protein; matriptase; matriptase/MT-SP1; mCAP3; membrane-type serine protease; membrane-type serine protease 1; MTSP1; MT-SP1; MTSP-1; Prostamin; protease, serine, 14 (epithin); PRSS14; Serine protease 14; serine protease TADG-15; SNC19; ST14; ST14 transmembrane serine protease matriptase; suppression of tumorigenicity 14; suppression of tumorigenicity 14 (colon carcinoma); suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin); suppressor of tumorigenicity 14 protein; Suppressor of tumorigenicity 14 protein homolog; suppressor of tumorigenicity protein 14; TADG15; TADG-15; Tmprss14; tumor associated differentially expressed gene 15 protein; tumor-associated differentially-expressed gene 15 protein

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19143, 6768

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P56677, Q9Y5Y6

Gene Symbols:
ST14

Immunogen:
A synthesized peptide derived from human ST14(Accession Q9Y5Y6), corresponding to amino acid residues Y658-F708.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG