PIPA599720

SPHK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599720-Each-of-1 In Stock ₹ 44,705.10

PIPA599720 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

SPHK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Sphk2

Gene Alias

C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

56848

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q9NRA0

Gene Symbols

Sphk2

Immunogen

A synthesized peptide derived from human SPHK2(Accession Q9NRA0), corresponding to amino acid residues G56-R106.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total SPHK2
  • SPHK2, along with SPHK1, catalyzes the phosphorylation of sphingosine producing the signaling molecule sphingosine-1-phosphate (S1P)
  • S1P signals through G-protein coupled receptors and controls diverse cellular processes
  • Inhibitors of SPHKs are viewed as potential therapeutics for the treatment of cancer
  • SPHK2 is an important signaling molecule with intra- and extracellular functions and has been implicated in regulating cell differentiation, calcium mobilization from intracellular stores, and apoptosis
  • The cell surface receptors for S1P are the EDG family of G protein-coupled receptors (S1P Receptors)
  • These receptors couple to multiple G proteins (e.g
  • S1P1 couples to Gi whereas S1P2 and S1P3 couple to Gq, G13 in addition to Gi) and regulate a extremely wide raange of cellular events including cell motility, survival, apoptosis, migration and cell-cell interaction
  • Important roles for S1P have also been reported in regulation of cardiogenesis, vascular maturation, oocyte survival, immune cell trafficking, cells of the neuronal system and bone cells
  • S1P levels are regulated by the activity of Sphk (Sphk1 and Sphk2).

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA599720

--


Antigen:
SPHK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Sphk2

Gene Alias:
C76851; SK 2; SK2; SK-2; Sphingosine kinase 2; sphingosine kinase type 2; Sphk2; SPK 2; SPK-2; Spk2, Sk2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56848

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9NRA0

Gene Symbols:
Sphk2

Immunogen:
A synthesized peptide derived from human SPHK2(Accession Q9NRA0), corresponding to amino acid residues G56-R106.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599722

--


Antigen:
ZNF280A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ZNF280A

Gene Alias:
3'OY11.1; SUHW1; Suppressor of hairy wing homolog 1; zinc finger protein 280; zinc finger protein 280A; Zinc finger protein 636; ZNF280; ZNF280A; ZNF636

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
129025

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P59817

Gene Symbols:
ZNF280A

Immunogen:
A synthesized peptide derived from human ZNF280A(Accession P59817), corresponding to amino acid residues W443-I493.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599723

--


Antigen:
SS18

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SS18

Gene Alias:
D130059H17; MGC116875; Protein SSXT; Protein SYT; SS18; SS18, nBAF chromatin remodeling complex subunit; Ssxt; synovial sarcoma associated SS18-beta; synovial sarcoma associated SS18-delta; synovial sarcoma associated SS18-gamma; synovial sarcoma translocated to X chromosome protein; synovial sarcoma translocation; synovial sarcoma translocation, chromosome 18; synovial sarcoma, translocated to X chromosome; synovial sarcoma-associated Ss18-alpha; SYT

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6760

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15532

Gene Symbols:
SS18

Immunogen:
A synthesized peptide derived from human SS18(Accession Q15532), corresponding to amino acid residues M1-D37.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599724

--


Antigen:
TAB182

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TNKS1BP1

Gene Alias:
182 kDa tankyrase-1-binding protein; KIAA1741; TAB182; tankyrase 1 binding protein 1; tankyrase 1 binding protein 1, 182kDa; tankyrase 1-binding protein of 182 kDa; testis secretory sperm-binding protein Li 206a; TNKS1BP1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
85456

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9C0C2

Gene Symbols:
TNKS1BP1

Immunogen:
A synthesized peptide derived from human TNKS1BP1(Accession Q9C0C2), corresponding to amino acid residues H1605-A1655.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG