PIPA599739

WAVE1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA599739-Each-of-1 In Stock ₹ 44,705.10

PIPA599739 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

WAVE1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

WASF1

Gene Alias

AI195380; AI838537; homology of dictyostelium scar 1; KIAA0269; Protein WAVE-1; Scar; SCAR1; Verprolin homology domain-containing protein 1; WAS protein family; WAS protein family member 1; WAS protein family, member 1; WASF1; WASP family 1; WASP family protein member 1; WAVE; WAVE1; WAVE-1; Wiskott-Aldrich syndrome protein family member 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

83767, 8936

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8R5H6, Q92558

Gene Symbols

WASF1

Immunogen

A synthesized peptide derived from human WASF1(Accession Q92558), corresponding to amino acid residues A267-P317.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

Description

  • Antibody detects endogenous levels of total WAVE1
  • WASP (for Wiskott-Aldrich syndrome protein) and N-WASP are downstream effectors of Cdc42 that are implicated in actin polymerization and cytoskeletal organization
  • The WASP family also includes VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), which accumulate at focal adhesions and are also involved in the regulation of the actin cytoskeleton
  • The WAVE proteins are related to the WASP family proteins and are likewise involved in mediating actin reorganization downstream of the Rho family of small GTPases
  • The two protein homologs WAVE1 and WAVE2 specifically regulate membrane ruffling by inducing the formation of actin filament clusters in response to GTP binding and activating Rac
  • The WAVE proteins mediate this actin polymerization by cooperating with the Arp2/3 complex, a nucleation core, and thereby promoting the formation of actin filaments
  • WAVE1, which is also designated SCAR (for suppressor of cAR), is expressed primarily in the brain, while WAVE2 is widely expressed with the expression highest in peripheral blood leukocytes
  • WAVE3 forms a multiprotein complex that links receptor kinases and actin
  • Binding to actin occurs through a C-terminal verprolin homology domain in all family members
  • The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function.

Compare Similar Items

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Img

Thermo Scientific

PIPA599739

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Antigen:
WAVE1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
WASF1

Gene Alias:
AI195380; AI838537; homology of dictyostelium scar 1; KIAA0269; Protein WAVE-1; Scar; SCAR1; Verprolin homology domain-containing protein 1; WAS protein family; WAS protein family member 1; WAS protein family, member 1; WASF1; WASP family 1; WASP family protein member 1; WAVE; WAVE1; WAVE-1; Wiskott-Aldrich syndrome protein family member 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
83767, 8936

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8R5H6, Q92558

Gene Symbols:
WASF1

Immunogen:
A synthesized peptide derived from human WASF1(Accession Q92558), corresponding to amino acid residues A267-P317.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599740

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Antigen:
WAVE4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
__

Gene Alias:
__

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
A synthesized peptide derived from human WAVE4, corresponding to a region within C-terminal amino acids.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599741

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Antigen:
WDHD1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Wdhd1

Gene Alias:
A630092E18; Acidic nucleoplasmic DNA-binding protein 1; AND1; And-1; CHTF4; crm1; CRM1/XPO1 protein; CTF4; CTF4, chromosome transmission fidelity factor 4 homolog; D630024B06Rik; exportin 1 (CRM1 homolog); exportin 1 S homeolog; exportin-1; WD repeat and HMG-box DNA binding protein 1; WD repeat and HMG-box DNA-binding protein 1; WD repeat and HMG-box DNA-binding protein 1-like protein; WDHD1; XELAEV_18028477mg; Xpo; xpo1; xpo1.S

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11169

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O75717

Gene Symbols:
Wdhd1

Immunogen:
A synthesized peptide derived from human WDHD1(Accession O75717), corresponding to amino acid residues E726-E776.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA599742

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Antigen:
YEATS2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
YEATS2

Gene Alias:
BC042768; Kiaa1197; mKIAA1197; YEATS domain containing 2; YEATS domain-containing protein 2; Yeats2; YETS2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
208146, 55689

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q3TUF7, Q9ULM3

Gene Symbols:
YEATS2

Immunogen:
A synthesized peptide derived from human YEATS2(Accession Q9ULM3), corresponding to amino acid residues S349-A399.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG