PIPA599854

IL-28A Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA599854-Each-of-1 In Stock ₹ 44,705.10

PIPA599854 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

IL-28A

Classification

Polyclonal

Conjugate

Unconjugated

Gene

IFNL2

Gene Alias

cytokine Zcyto20, EG330496, Ifnl2, IFN-lambda2, IFN-lambda-2, Il28a, IL-28A, ILN, interferon lambda 2, interferon lambda-2, interferon, lambda 2, interferon-lambda 2, interferon-lambda2, Interleukin, interleukin 28A, interleukin 28A (interferon, lambda 2), interleukin-28A, ZCYTO20

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

282616

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8IZJ0

Gene Symbols

IFNL2

Immunogen

A synthesized peptide derived from human IFNL2(Accession Q8IZJ0), corresponding to amino acid residues M1-G33.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of total IL28A
  • IL-28A belongs to the IFN lambda family, a novel family of cytokines within the IL-10 superfamily
  • The three members of this family are IL-29 (IFN lambda 1), IL-28A (IFN lambda 2), and IL-28B (IFN lambda 3), and are also known as the type III Interferons.The IFN lambdas signal through a heterodimeric receptor of which one subunit, IL-10R2, is shared with other members of the superfamily
  • The second subunit, IFN lambda R1 or IL-28R alpha, is unique to the IFN lambdas
  • Signaling occurs through the Jak/STAT pathway in a similar manner as the type I IFN (IFN alpha/beta) and activates many of the same genes despite low sequence homology between the cytokines and receptors in the two families
  • Both IFN families display antiviral activity through the induction of antiviral protein production in target cells and the upregulation of MHC class I expression
  • These proteins also exhibit antiproliferative and antitumor effects, making them a possible alternative to IFN alpha cancer therapies
  • Unlike the type I IFN, which are able to stimulate most cells, response to IFN lambda stimulation appears to be limited to dendritic and some tumor cells due to the limited expression of IFN lambda R1
  • Another notable difference is the ability of the IFN lambda stimulation to drive dendritic cells towards the production of CD4+CD25+FoxP3+ regulatory T cells, suggesting a possible immunoregulatory role

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA599854

--


Antigen:
IL-28A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IFNL2

Gene Alias:
cytokine Zcyto20, EG330496, Ifnl2, IFN-lambda2, IFN-lambda-2, Il28a, IL-28A, ILN, interferon lambda 2, interferon lambda-2, interferon, lambda 2, interferon-lambda 2, interferon-lambda2, Interleukin, interleukin 28A, interleukin 28A (interferon, lambda 2), interleukin-28A, ZCYTO20

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
282616

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8IZJ0

Gene Symbols:
IFNL2

Immunogen:
A synthesized peptide derived from human IFNL2(Accession Q8IZJ0), corresponding to amino acid residues M1-G33.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA599855

--


Antigen:
TCCR

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Il27ra

Gene Alias:
class I cytokine receptor; CRL1; CRL1IL-27R; cytokine receptor family, class 1 (WSXWS), member 1; cytokine receptor WSX-1; Cytokine receptor-like 1; il-27 receptor; IL-27 receptor subunit alpha; IL27R; IL-27R; IL-27R subunit alpha; IL27RA; IL-27RA; IL-27R-alpha; interleukin 27 receptor subunit alpha; interleukin 27 receptor, alpha; interleukin-27 receptor subunit alpha; T cell cytokine receptor; T cell cytokine receptor; cytokine receptor family, class 1 (WSXWS), member 1; TCCR; T-cell cytokine receptor type 1; Type I T-cell cytokine receptor; UNQ296/PRO336; WSX1; WSX-1; ZcytoR1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
9466

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6UWB1

Gene Symbols:
Il27ra

Immunogen:
A synthesized peptide derived from human IL27RA(Accession Q6UWB1), corresponding to amino acid residues T30-T80.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA599856

--


Antigen:
PSD4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PSD4

Gene Alias:
ADP-ribosylation factor guanine nucleotide-exchange factor 6; EFA6B; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B; exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B; exchange factor for ARF6 B; PH and SEC7 domain-containing protein 4; pleckstrin and Sec7 domain containing 4; pleckstrin homology and SEC7 domain-containing protein 4; PSD4; SEC7 homolog; telomeric of interleukin-1 cluster protein; TIC

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23550

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8NDX1

Gene Symbols:
PSD4

Immunogen:
A synthesized peptide derived from human PSD4(Accession Q8NDX1), corresponding to amino acid residues Q771-G821.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA599857

--


Antigen:
RGMB

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RGMB

Gene Alias:
1110059F19Rik; DRAGON; DRG11-responsive axonal guidance and outgrowth of neurite; repulsive guidance molecule B; repulsive guidance molecule family member B; RGM domain family member B; RGM domain family, member B; RGMB

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
285704

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q6NW40

Gene Symbols:
RGMB

Immunogen:
A synthesized peptide derived from human RGMB(Accession Q6NW40), corresponding to amino acid residues L110-Y160.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG