PITCR2645
TCR V beta 5b Monoclonal Antibody (W112), FITC, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PITCR2645-Each-of-1 | In Stock | ₹ 39,427.00 |
PITCR2645 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,427.00
GST (18%): ₹ 7,096.86
Total Price: ₹ 46,523.86
Antigen
TCR V beta 5b
Classification
Monoclonal
Concentration
0.15 mg/mL
Formulation
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.
0
Gene Symbols
TRB
Immunogen
Human TCR Vb5.3
Quantity
150 Tests
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG1
Applications
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot
Clone
W112
Conjugate
FITC
Gene
TRB
Gene Alias
T cell receptor beta locus; TCRB; TRB; TRB@
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
6957
Content And Storage
4° C, store in dark
Form
Liquid
Related Products
Description
- TCR2645 targets TCR V beta 5b in FACS, IHC(F), IP, TCA, and WB applications and shows reactivity with Human samples
- The TCR2645 immunogen is human TCR Vb5.3
- The ability of T cell receptors (TCR) to discriminate foreign from self-peptides presented by major histocompatibility complex (MHC) class II molecules is essential for an effective adaptive immune response
- TCR recognition of self-peptides has been linked to autoimmune disease
- Mutant self-peptides have been associated with tumors
- Engagement of TCRs by a family of bacterial toxins know as superantigens has been responsible for toxic shock syndrome
- Autoantibodies to V beta segments of T cell receptors have been isolated from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE)
- The autoantibodies block TH1-mediated inflammatory autodestructive reactions and are believed to be a method by which the immune system compensates for disease (ref5)
- T Cell and TCR Diversity Most human T cells express the TCR alpha-beta and either CD4 or CD8 molecule (single positive, SP)
- A small number of T cells lack both CD4 and CD8 (double negative, DN)
- Increased percentages of alpha-beta DN T cells have been identified in some autoimmune and immunodeficiency disorders
- Gamma-delta T cells are primarily found within the epithelium
- They show less TCR diversity and recognize antigens differently than alpha-beta T cells
- Subsets of gamma-delta T cells have shown antitumor and immunoregulatory activity.
Compare Similar Items
Show Difference
Antigen: TCR V beta 5b
Classification: Monoclonal
Concentration: 0.15 mg/mL
Formulation: PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.: 0
Gene Symbols: TRB
Immunogen: Human TCR Vb5.3
Quantity: 150 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot
Clone: W112
Conjugate: FITC
Gene: TRB
Gene Alias: T cell receptor beta locus; TCRB; TRB; TRB@
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 6957
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
TCR V beta 5b
Classification:
Monoclonal
Concentration:
0.15 mg/mL
Formulation:
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.:
0
Gene Symbols:
TRB
Immunogen:
Human TCR Vb5.3
Quantity:
150 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot
Clone:
W112
Conjugate:
FITC
Gene:
TRB
Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
6957
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: TCR V beta 8a
Classification: Monoclonal
Concentration: 0.15 mg/mL
Formulation: PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.: 0
Gene Symbols: TRB
Immunogen: Human TCR V beta 8
Quantity: 200 Tests
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot
Clone: 16G8
Conjugate: FITC
Gene: TRB
Gene Alias: T cell receptor beta locus; TCRB; TRB; TRB@
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6957
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
TCR V beta 8a
Classification:
Monoclonal
Concentration:
0.15 mg/mL
Formulation:
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.:
0
Gene Symbols:
TRB
Immunogen:
Human TCR V beta 8
Quantity:
200 Tests
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation, Western Blot
Clone:
16G8
Conjugate:
FITC
Gene:
TRB
Gene Alias:
T cell receptor beta locus; TCRB; TRB; TRB@
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6957
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: TCR V beta 12
Classification: Monoclonal
Concentration: 0.15 mg/mL
Formulation: PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.: P04435
Gene Symbols: TRB
Immunogen: Human TCR V beta 12
Quantity: 200 Tests
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2b
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation
Clone: S511
Conjugate: FITC
Gene: TRB
Gene Alias: T cell receptor beta chain; T cell receptor beta locus; TCRB; TCRbeta; Tib; TRB; TRB@
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 6957
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
TCR V beta 12
Classification:
Monoclonal
Concentration:
0.15 mg/mL
Formulation:
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.:
P04435
Gene Symbols:
TRB
Immunogen:
Human TCR V beta 12
Quantity:
200 Tests
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2b
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunoprecipitation, T-Cell Activation
Clone:
S511
Conjugate:
FITC
Gene:
TRB
Gene Alias:
T cell receptor beta chain; T cell receptor beta locus; TCRB; TCRbeta; Tib; TRB; TRB@
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
6957
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: TCR V alpha 2
Classification: Monoclonal
Concentration: 0.15 mg/mL
Formulation: PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Human TCR V alpha-2
Quantity: 200 Tests
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry
Clone: F1
Conjugate: FITC
Gene: __
Gene Alias: TCRVA; TCRVA2; V alpha 2; V alpha-2 TCR; Va 2; Va2; Valpha 2; Valpha2
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
TCR V alpha 2
Classification:
Monoclonal
Concentration:
0.15 mg/mL
Formulation:
PBS with 0.5% BSA and 0.1% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Human TCR V alpha-2
Quantity:
200 Tests
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry
Clone:
F1
Conjugate:
FITC
Gene:
__
Gene Alias:
TCRVA; TCRVA2; V alpha 2; V alpha-2 TCR; Va 2; Va2; Valpha 2; Valpha2
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark
Form:
Liquid