R02021E

beta-2 Microglobulin Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 R02021E-Each-of-1 In Stock ₹ 51,397.50

R02021E - Each of 1

₹ 51,397.50

In Stock

Quantity

1

Base Price: ₹ 51,397.50

GST (18%): ₹ 9,251.55

Total Price: ₹ 60,649.05

Antigen

beta-2 Microglobulin

Classification

Polyclonal

Conjugate

Unconjugated

Gene

B2m

Gene Alias

B2m; B2-microglobulin; b2m-W01; b2m-W03; b2m-Z01; b2m-Z02; b2m-Z03; Beta 2 microglobin; Beta 2 microglobulin; beta 2-microglobulin; beta chain of MHC class I molecules; Beta2 microglobulin; beta-2 microglobulin; beta-2 microglobulin preprotein; beta2m; beta2-m; beta-2-microglobin; beta-2-microglobulin; beta-2-microglobulin C-terminal fragment (55 AA); Beta-2-microglobulin form pI 5.3; B-F; CDABP0092; HDCMA22P; IMD43; Lactollin; Ly-m11; MHC Class I; microglobulin beta-2; Orla-B2m

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

567

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ELISA, Immunocytochemistry, Immunodiffusion, Immunoelectrophoresis, Western Blot

Concentration

1.0 mg/mL

Formulation

20mM MES with 0.02% sodium azide; pH 5.8

Gene Accession No.

P61769

Gene Symbols

B2m

Immunogen

Purified human beta-2-microglobulin

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Description

  • Purity: IgG is > 96.5% total protein by SDS-PAGE
  • Becker titer results showed > 0.330 mg/mL (antigen/antibody)
  • Beta-2-microglobulin (B2M) is a 12-14 kDa protein that is a subunit of the major histocompatibility complex (MHC) class I
  • Human beta 2 Microglobulin associated with HLA Class I antigens are expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells, but is absent on erythrocytes
  • Beta-2 microglobulin is also found in free form in the plasma
  • The amino acid sequence of Beta-2-microglobulin is homologous to the constant regions of immunoglobulin heavy and light chains, with a predominantly beta pleated sheet structure
  • The protein is ubiquitously expressed in the cytoplasm, and is involved in antigen processing and presentation
  • Beta-2-microglobulin also plays a role in TCR signaling, and downstream signaling in naive CD8+ cells
  • Beta 2-microglobulin is encoded by the B2M gene located on chromosome 15
  • A mutation in the Beta-2-microglobulin gene has been shown to result in hypercatabolic hypoproteinemia
  • Levels of beta 2 microglobulin can be used to assess renal function in kidney transplant recipients
  • Beta-2-microglobulin that protein can be used as a prognostic marker for HIV infection.

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R02021E

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Antigen:
beta-2 Microglobulin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
B2m

Gene Alias:
B2m; B2-microglobulin; b2m-W01; b2m-W03; b2m-Z01; b2m-Z02; b2m-Z03; Beta 2 microglobin; Beta 2 microglobulin; beta 2-microglobulin; beta chain of MHC class I molecules; Beta2 microglobulin; beta-2 microglobulin; beta-2 microglobulin preprotein; beta2m; beta2-m; beta-2-microglobin; beta-2-microglobulin; beta-2-microglobulin C-terminal fragment (55 AA); Beta-2-microglobulin form pI 5.3; B-F; CDABP0092; HDCMA22P; IMD43; Lactollin; Ly-m11; MHC Class I; microglobulin beta-2; Orla-B2m

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
567

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunodiffusion, Immunoelectrophoresis, Western Blot

Concentration:
1.0 mg/mL

Formulation:
20mM MES with 0.02% sodium azide; pH 5.8

Gene Accession No.:
P61769

Gene Symbols:
B2m

Immunogen:
Purified human beta-2-microglobulin

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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Gene:
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Gene Symbols:
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Isotype:
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Classification:
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Classification:
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Gene:
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Immunogen:
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Primary or Secondary:
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Target Species:
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Isotype:
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