RB087R1

GFAP (Glial Fibrillary Acidic Protein) Rabbit Polyclonal Antibody, Epredia™

Manufacturer: Fischer Scientific

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Antigen

GFAP (Glial Fibrillary Acidic Protein)

Classification

Polyclonal

Conjugate

Unconjugated

Immunogen

GFAP isolated from cow spinal cord

Regulatory Status

RUO

Primary or Secondary

Primary

Form

Prediluted

Applications

Immunohistochemistry (Paraffin)

Clone

Polyclonal

Host Species

Rabbit

Quantity

1 mL

Research Discipline

Neuroscience

Target Species

Bovine, Chicken, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Rat

Isotype

IgG

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Description

  • Glial Fibrillary Acidic Protein (GFAP) is specific to astrocytes (i.e., glial cells) and ependymal cells of the central nervous system
  • Host Species: Rabbit Isotype: IgG Species Reactivity: Human, Monkey, Cow, Sheep, Guinea Pig, Chicken, Mouse, Rat and Hamster
  • Others not known
  • Epitope: Not determined Immunogen: GFAP isolated from cow spinal cord Molecular Weight: 51-52 kDa Positive Control: Brain or astrocytoma Cellular Localization: Cytoplasmic Ab-4 stains astrocytes, glial cells, ependymal cells and their corresponding tumors
  • In the peripheral nervous system, Schwann cells, satellite cells, and enteric glial cells are stained
  • Weak staining of axons has been observed
  • Absorption studies show that this is caused by a cross-reaction with neurofilament protein
  • Ab-4 is particularly useful for distinguishing neoplasms of astrocytic origin from other neoplasms in the central nervous system by immunohistochemistry
  • Recommended for: Immunohistochemistry (Formalin/paraffin) Note: USA: RUO; Int'l: RUO