Epredia™ Lab Vision™ Pax-5 Rabbit Polyclonal Antibody with BSA and azide

Description

• Description PAX-5 is a B cell specific activator protein (BSAP)
• In the early stages of B cell developmemt, PAX-5 influences the expression of several B-cell-specific genes, such as CD19 and CD20
• PAX-5 is expressed primarily inpro-, pre-, and mature B cells, but not in plasma cells
• Interestingly, PAX-5 mRNA is transiently detected in the mesencephalon and spinal cord during embryogenesis
• Expression then shifts to the fetal liver and correlates with the onset of B lymphopoiesis
• This indicates that PAX-5 is important in B cell development, but may also have a role in proper neuronal development
• Host Species: Rabbit Species Reactivity: Human, Mouse, Rat
• Others not tested
• Epitope: C-terminal Immunogen: Synthetic peptide derived from C-terminus of human PAX-5 protein Molecular Weight: 50kDa Positive Control: Tonsil, Raji cells Cellular Localization: Nuclear Recommended for: Immunohistochemistry (Formalin/paraffin) Western Blotting