RM2101RQ

Epredia™ Lab Vision™ β-Catenin Rabbit Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Catenin, beta

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

A synthetic peptide derived from near the N-terminus of human beta-catenin

Regulatory Status

IVD

Primary or Secondary

Primary

Applications

Immunohistochemistry (Paraffin)

Clone

E247

Host Species

Rabbit

Quantity

12 mL

Research Discipline

Cancer and Tumor Biology

Form

Ready-to-Use

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Description

  • The catenins (α, β and γ) are ubiquitously expressed cytoplasmic proteins associated with E-cadherin at cellular junctions
  • β-catenin also binds to N-cadherin and co-immunoprecipitates with APC
  • Cadherin/catenin complexes are linked to the cytoskeleton via a direct association between α-actinin and α-catenin
  • Increased tyrosine phosphorylation can disrupt catenin-cadherin complexes, influencing cellular adhesion
  • Mutations in the catenin gene, CTNNB1, have been implicated in its accumulation and various forms of carcinomas
  • Host Species: Rabbit Clone: E247 Species Reactivity: Human
  • Others not known
  • Immunogen: A synthetic peptide derived from near the N-terminus of human β-catenin Molecular Weight: 92 kDa Positive Control: Breast CA Cellular Localization: Cell Membrane Recommended for: Immunohistochemistry (Formalin/paraffin)

Compare Similar Items

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Img

Fischer Scientific

RM2101RQ

--


Antigen:
Catenin, beta

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
A synthetic peptide derived from near the N-terminus of human beta-catenin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Applications:
Immunohistochemistry (Paraffin)

Clone:
E247

Host Species:
Rabbit

Quantity:
12 mL

Research Discipline:
Cancer and Tumor Biology

Form:
Ready-to-Use

Img

Fischer Scientific

RM2101S

--


Antigen:
Catenin, beta

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
A synthetic peptide derived from near the N-terminus of human beta-catenin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Applications:
Immunohistochemistry (Paraffin)

Clone:
E247

Host Species:
Rabbit

Quantity:
1 mL

Research Discipline:
Cancer and Tumor Biology

Form:
Concentrated

Img

Fischer Scientific

RM2101S0

--


Antigen:
Catenin, beta

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
A synthetic peptide derived from near the N-terminus of human beta-catenin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Applications:
Immunohistochemistry (Paraffin)

Clone:
E247

Host Species:
Rabbit

Quantity:
100 μL

Research Discipline:
Cancer and Tumor Biology

Form:
Concentrated

Img

Fischer Scientific

RM2104R1

--


Antigen:
Prostate Specific Antigen (PSA)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
A synthetic peptide corresponding to residues near the C-terminus of human PSA

Regulatory Status:
ASR

Primary or Secondary:
Primary

Applications:
Immunohistochemistry (Paraffin)

Clone:
EP1588Y

Host Species:
Rabbit

Quantity:
1 mL

Research Discipline:
Cancer and Tumor Biology

Form:
Prediluted