RM9108RQ

Epredia™ Lab Vision™ ALK (Anaplastic Lymphoma Kinase)/p80 Rabbit Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

ALK (Anaplastic Lymphoma Kinase)/p80

Classification

Monoclonal

Conjugate

Unconjugated

Immunogen

Recombinant protein corresponding to a region, which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript

Regulatory Status

IVD

Primary or Secondary

Primary

Applications

Immunohistochemistry (Paraffin)

Clone

SP8

Host Species

Rabbit

Quantity

12 mL

Research Discipline

Cancer and Tumor Biology

Form

Ready-to-Use

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Description

  • Description Recognizes a human p80 protein, identified as a hybrid of the anaplastic lymphoma kinase (ALK) gene and the nucleophosmin (NPM) gene resulting from the t(2;5)(p23;q35) translocation found in 30-50% of CD30+ large cell lymphomas (1)
  • This rabbit monoclonal antibody can be used to detect p80 in these lymphomas and may also be used to detect a recently described subtype of large B cell lymphoma, which expresses the full-length ALK protein (2)
  • Host Species: Rabbit Clone: SP8 Isotype: IgG Species Reactivity: Human
  • Others not tested
  • Epitope: Not determined Immunogen: Recombinant protein corresponding to a region which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript Positive Control: Anaplastic lymphoma Cellular Localization: Cytoplasmic + nuclear Clone SP8 is excellent for staining of formalin/paraffin with no special pretreatment Recommended for: Immunohistochemistry (Formalin/paraffin)

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Fischer Scientific

RM9108RQ

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Antigen:
ALK (Anaplastic Lymphoma Kinase)/p80

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein corresponding to a region, which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript

Regulatory Status:
IVD

Primary or Secondary:
Primary

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP8

Host Species:
Rabbit

Quantity:
12 mL

Research Discipline:
Cancer and Tumor Biology

Form:
Ready-to-Use

Img

Fischer Scientific

RM9108S0

--


Antigen:
ALK (Anaplastic Lymphoma Kinase)/p80

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
Recombinant protein corresponding to a region, which spans the tyrosine kinase catalytic domain and part of the C-terminus of the NPM-ALK transcript

Regulatory Status:
IVD

Primary or Secondary:
Primary

Applications:
Immunohistochemistry (Paraffin)

Clone:
SP8

Host Species:
Rabbit

Quantity:
100 μL

Research Discipline:
Cancer and Tumor Biology

Form:
Concentrated

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Fischer Scientific

RM9111R1

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Antigen:
Synaptophysin (Neuroendocrine Marker)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
A synthetic peptide of human synaptophysin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Applications:
Western Blot

Clone:
SP11

Host Species:
Rabbit

Quantity:
1 mL

Research Discipline:
Neuroscience

Form:
Prediluted

Img

Fischer Scientific

RM9111R7

--


Antigen:
Synaptophysin (Neuroendocrine Marker)

Classification:
Monoclonal

Conjugate:
Unconjugated

Immunogen:
A synthetic peptide of human synaptophysin

Regulatory Status:
IVD

Primary or Secondary:
Primary

Applications:
Western Blot

Clone:
SP11

Host Species:
Rabbit

Quantity:
7 mL

Research Discipline:
Neuroscience

Form:
Prediluted