ST1558100UG

MilliporeSigma™ anti-ALOX12 Clone: 2D10,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 ST1558100UG-Each-of-1 In Stock ₹ 46,364.96

ST1558100UG - Each of 1

₹ 46,364.96

In Stock

Quantity

1

Base Price: ₹ 46,364.96

GST (18%): ₹ 8,345.693

Total Price: ₹ 54,710.653

Antigen

ALOX12

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Mouse

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Applications

ELISA, Immunoblot, Immunoblot

Clone

2D10

Formulation

In PBS, pH 7.2.

Immunogen

A recombinant polypeptide corresponding to amino acids 564-664 of human ALOX12, expressed as a GST fusion protein

Regulatory Status

RUO

Test Specificity

Recognizes the ALOX12 protein.

Content And Storage

−20°C

Isotype

IgG2a

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Description

  • Specifically detects ALOX12 Clone: 2D10 in Human samples, and it is validated for ELISA, Immuno Blotting Lipoxygenases (LOXs) are a family of non-heme iron dioxygenases that are involved in the production and metabolism of fatty acid hydroperoxidases
  • There are six lipoxygenase isozymes; 5-LOX, 12R-LOX, 12S-LOX, 15-LOX-1 and 15-LOX-2, which catalyze the regio-selective addition of oxygen into arachidonic acid, and epidermal LOX (E-LOX) which metabolizes 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE) to a specific epoxyalcohol compound
  • Different isozymes have different physiological roles; 5-, 12R-, 12S- and 15-LOX-1 have proliferative, antiapoptotic and angiogenic functions whilst 15-LOX-2 has roles in differentiation, growth arrest and the induction of apoptosis
  • E-LOX, the most divergent member of this family, is involved in terminal differentiation of keratinocytes and has a major role in skin barrier function
  • Perturbations in lipoxygenase enzymes have been implicated in various human diseases including bronchial asthma, atherosclerosis, osteoporosis and some cancers.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

ST1558100UG

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Antigen:
ALOX12

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
ELISA, Immunoblot, Immunoblot

Clone:
2D10

Formulation:
In PBS, pH 7.2.

Immunogen:
A recombinant polypeptide corresponding to amino acids 564-664 of human ALOX12, expressed as a GST fusion protein

Regulatory Status:
RUO

Test Specificity:
Recognizes the ALOX12 protein.

Content And Storage:
−20°C

Isotype:
IgG2a

Img

MilliporeSigma™

ST1564100UG

--


Antigen:
CYP19A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Host Species:
Rabbit

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Immunoblot

Clone:
__

Formulation:
In PBS, pH 7.2.

Immunogen:
Full-length, human CYP19A1 (aa 1-503)

Regulatory Status:
RUO

Test Specificity:
Recognizes the CYP19A1 protein in human liver tissue.

Content And Storage:
−20°C

Isotype:
IgG1

Img

MilliporeSigma™

ST1568100UG

--


Antigen:
DEFB4

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
ELISA, Immunoblot, Immunoblot

Clone:
4C4

Formulation:
In PBS, pH 7.2.

Immunogen:
A recombinant polypeptide corresponding to amino acids 24-65 of human DEFB4, expressed as a GST fusion protein

Regulatory Status:
RUO

Test Specificity:
Recognizes the DEFB4 protein.

Content And Storage:
−20°C

Isotype:
IgG1

Img

MilliporeSigma™

ST1579100UG

--


Antigen:
FADS1

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
ELISA, Immunoblot, Immunoblot, Immunohistochemistry (Paraffin)

Clone:
2D9

Formulation:
In PBS, pH 7.2.

Immunogen:
A recombinant polypeptide corresponding to amino acids 1-100 of human FADS1, expressed as a GST fusion protein

Regulatory Status:
RUO

Test Specificity:
Recognizes the ∽50-55kDa FADS1 protein in HeLa cells and human skeletal muscle tissue.

Content And Storage:
−20°C

Isotype:
IgG2a