Description

• Application: The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate mitigates UVB-induced PGE(2) synthesis by keratinocytes.: This study investigates the protective effects of D-panthenol, combined with other compounds, against UVB-induced inflammation in keratinocytes. The results highlight D-panthenol′s role in skin care formulations aimed at reducing UV-induced damage and inflammation (Tan et al., 2024). Protective Effect of D-Panthenol in Rhabdomyolysis-Induced Acute Kidney Injury.: This research explores the protective properties of D-panthenol in mitigating acute kidney injury caused by rhabdomyolysis. The findings suggest potential therapeutic applications for D-panthenol in renal protection and recovery (Semenovich et al., 2022). Alpha-Glycerylphosphorylcholine and D-Panthenol Eye Drops in Patients Undergoing Cataract Surgery.: This clinical study examines the efficacy of eye drops containing D-panthenol in patients undergoing cataract surgery, demonstrating its potential to enhance postoperative recovery and eye health (Martone et al., 2022). Common Cosmetic Compounds Can Reduce Air Pollution-Induced Oxidative Stress and Pro-Inflammatory Response in the Skin.: This study highlights the role of D-panthenol in protecting the skin against oxidative stress and inflammation caused by air pollution, emphasizing its importance in cosmetic formulations for urban environments (Hergesell et al., 2022).
• Biochem/physiol Actions: D-Panthenol is the alcohol analogue and biological precursor of D-pantothenic acid. These analogues are precursors in the biosynthesis of coenzyme A. D-Panthenol and D-Pantothenic acid are used in a variety of skin protection products. D-pantothenic acid may have a role in controlling keratinocyte proliferation and differentiation. D-Panthenol may be used for studies of skin protection emulsions from UV irradiation and as a humectant.