F4767

Filipin III from Streptomyces filipinensis

≥85% (HPLC)

Manufacturer: Sigma Aldrich

CAS Number: 480-49-9

Synonym(S): Filimarisin

Select a Size

Pack Size SKU Availability Price
1 MG F4767-1-MG In Stock ₹ 21,162.88
5 MG F4767-5-MG In Stock ₹ 70,622.30

F4767 - 1 MG

₹ 21,162.88

In Stock

Quantity

1

Base Price: ₹ 21,162.88

GST (18%): ₹ 3,809.318

Total Price: ₹ 24,972.198

Quality Level

300

Assay

≥85% (HPLC)

form

powder

mp

163-180  °C

solubility

methanol: 9.80-10.20 mg/mL, clear, colorless to yellow

antibiotic activity spectrum

fungiyeast

Mode of action

cell membrane | interferes

storage temp.

−20°C

SMILES string

CCCCCC(O)C1C(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC(O)C(C)=C\C=C\C=C\C=C\C=C\C(O)C(C)OC1=O

InChI

1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14-

Other Options

Image Product Name Manufacturer Price Range
62501NB
Tocris Bioscience™ Filipin III
Tocris Bioscience™ ₹ 25,154.64
50-176-0187
Sigma Aldrich Fine Chemicals Biosciences Filipin III from Streptomyces filipinensis | 480-49-9 | MFCD00466923 | 5 mg
Sigma Aldrich Fine Chemicals Biosciences ₹ 81,778.25
NC9384264
Cayman Chemical Filipin III, 480-49-9, 1 mg
Cayman Chemical ₹ 14,955.89
50-247-6928
eMolecules​ Medchem Express / Filipin III / 1mg / 482204632 / HY-N6718 / / 480-49-9 / MFCD30742956 / 654.838 / C35H58O11
eMolecules​ ₹ 24,559.14
CS-0099763
Filipin III
ChemScene ₹ 16,684.20 - ₹ 62,031.00
AB74233
480-49-9 | Filipin iii
A2B Chem ₹ 11,721.72 - ₹ 46,373.52

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Description

  • Application: Filipin has been used in a double staining procedure as a probe for the detection of lipoproteins in polyacrylamide gel and immobilized on nitrocellulose membranes. It is also widely used to localize and quantitate unesterified cholesterol by virtue of a specific fluorescent complex.
  • Biochem/physiol Actions: Filipin is a polyene macrolide antibiotic and antifungal. The antifungal mechanism of action may be due to altering membrane permeability and associated functions by binding to membrane sterols. Filipin inhibits prion protein (PrP) endocytosis and causes the release of PrP from the plasma membrane.
  • Other Notes: Filipin III is the major component of 8 isomeric components in filipin.

SAFETY INFORMATION

Pictograms

GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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300

Assay:
≥85% (HPLC)

form:
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163-180  °C

solubility:
methanol: 9.80-10.20 mg/mL, clear, colorless to yellow

antibiotic activity spectrum:
fungiyeast

Mode of action:
cell membrane | interferes

storage temp.:
−20°C

SMILES string:
CCCCCC(O)C1C(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC(O)C(C)=C\C=C\C=C\C=C\C=C\C(O)C(C)OC1=O

InChI:
1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14-

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InChI:
1S/C7H5FO/c8-7-4-2-1-3-6(7)5-9/h1-5H