Filipin complex
powder, ≥70% (UV)
Manufacturer: Sigma Aldrich
CAS Number: 11078-21-0
Synonym(S): Filimarisin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 25 MG | F9765-25-MG | In Stock | ₹ 22,678.38 |
| 50 MG | F9765-50-MG | In Stock | ₹ 41,113.35 |
F9765 - 25 MG
In Stock
Quantity
1
Base Price: ₹ 22,678.38
GST (18%): ₹ 4,082.108
Total Price: ₹ 26,760.488
product name
Filipin complex from Streptomyces filipinensis, ≥70% (UV)
biological source
Streptomyces sp. (Streptomyces filipinensis)
Quality Level
200
Assay
≥70% (UV)
form
powder
solubility
methanol: 9.80-10.20 mg/mL, clear to hazy, yellow to very deep greenish-yellow
antibiotic activity spectrum
fungi
Mode of action
cell membrane | interferes
storage temp.
−20°C
InChI
1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14+/t24-,25+,26-,27+,28-,29+,30+,31-,32+,33+,34-/m1/s1
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Medchemexpress LLC HY-N6716 5mg Medchemexpress, Filipin complex CAS:11078-21-0 Purity:>98% | Medchemexpress LLC | ₹ 5,929.31 | |
| | Sigma Aldrich Fine Chemicals Biosciences Filipin complex from Streptomyces filipinensis >=70% (UV) | 11078-21-0 | MFCD00131073 | 25MG | Sigma Aldrich Fine Chemicals Biosciences | ₹ 22,954.04 | |
 | 11078-21-0 | Filipin | A2B Chem | ₹ 4,620.24 - ₹ 20,619.96 |
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Description
- General description: Chemical structure: macrolide
- Application: Filipin complex from Streptomyces filipinensis has been used as a profluorescence probe to detect the free cholesterol in cell.[1][2][3]
- Biochem/physiol Actions: Filipin is a polyene macrolide antibiotic and antifungal. The antifungal mechanism of action is unclear but may be due to altering membrane permeability. Filipin binds to model crystalline phase lipid bilayers containing cholesterol, and to liquid phase bilayers with or without cholesterol, in an orientation that forms membrane pores.It both inhibits prion protein (PrP) endocytosis and causes the release of PrP from the plasma membrane.
- Other Notes: Filipin contains 8 isomeric components, with filipin III as the major component.
SAFETY INFORMATION
Pictograms
Signal Word
Warning
Hazard Statements
Precautionary Statements
P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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product name: Filipin complex from Streptomyces filipinensis, ≥70% (UV)
biological source: Streptomyces sp. (Streptomyces filipinensis)
Quality Level: 200
Assay: ≥70% (UV)
form: powder
solubility: methanol: 9.80-10.20 mg/mL, clear to hazy, yellow to very deep greenish-yellow
antibiotic activity spectrum: fungi
Mode of action: cell membrane | interferes
storage temp.: −20°C
InChI: 1S/C35H58O11/c1-4-5-11-16-31(42)34-33(44)22-29(40)20-27(38)18-25(36)17-26(37)19-28(39)21-32(43)23(2)14-12-9-7-6-8-10-13-15-30(41)24(3)46-35(34)45/h6-10,12-15,24-34,36-44H,4-5,11,16-22H2,1-3H3/b7-6+,10-8+,12-9+,15-13+,23-14+/t24-,25+,26-,27+,28-,29+,30+,31-,32+,33+,34-/m1/s1
product name: __
biological source: __
Quality Level: 200
Assay: __
form: powder
solubility: DMSO: soluble
antibiotic activity spectrum: neoplastics
Mode of action: DNA synthesis | interferes
storage temp.: −20°C
InChI: 1S/C10H13FN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21)
product name: __
biological source: goat
Quality Level: 200
Assay: __
form: buffered aqueous solution
solubility: __
antibiotic activity spectrum: __
Mode of action: __
storage temp.: __
InChI: __
