R3255
13-cis-Retinoic acid
≥98% (HPLC)
Manufacturer: Sigma Aldrich
CAS Number: 4759-48-2
Synonym(S): Isotretinoin
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 100 MG | R3255-100-MG | In Stock | ₹ 7,339.35 |
| 250 MG | R3255-250-MG | In Stock | ₹ 14,126.63 |
| 500 MG | R3255-500-MG | In Stock | ₹ 24,778.43 |
R3255 - 100 MG
In Stock
Quantity
1
Base Price: ₹ 7,339.35
GST (18%): ₹ 1,321.083
Total Price: ₹ 8,660.433
Quality Level
200
Assay
≥98% (HPLC)
form
powder
technique(s)
HPLC: suitable
color
yellow to yellow-orange
mp
172-175 °C (lit.)
storage temp.
−20°C
SMILES string
[H]\C(C(O)=O)=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C
InChI
1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
InChI key
SHGAZHPCJJPHSC-XFYACQKRSA-N
Other Options
| Image | Product Name | Manufacturer | Price Range | |
|---|---|---|---|---|
 | Enzo Life Sciences 13-cis-Retinoic acid (500mg). CAS: 4759-48-2 | Enzo Life Sciences | ₹ 22,532.23 | |
 | Medchemexpress LLC HY-15127 100mg , Isotretinoin CAS:4759-48-2 Purity:>98% | Medchemexpress LLC | ₹ 5,390.28 | |
 | eMolecules Ambeed / (2Z4E6E8E)-37-Dimethyl-9-(266-trimethylcyclohex-1-en-1-yl)nona-2468-tetraenoic acid / 1g / 490526024 / A181906 / / 4759-48-2 / MFCD00079542 / 300.442 / C20H28O2 | eMolecules | ₹ 2,251.94 | |
 | Isotretinoin | Supelco | ₹ 14,137.45 | |
| | Isotretinoin | Sigma Aldrich | ₹ 14,267.35 | |
| | Isotretinoin | Sigma Aldrich | ₹ 46,222.75 | |
| | 13-cis-Retinoic acid | Sigma Aldrich | ₹ 7,339.35 - ₹ 24,778.43 | |
 | Isotretinoin | ChemScene | ₹ 855.60 - ₹ 17,539.80 | |
 | 4759-48-2 | 13-cis-Retinoic Acid | A2B Chem | ₹ 855.60 - ₹ 18,224.28 |
Related Products
Description
- Application: 13-cis-Retinoic acid has been used:as a component of fresh media for LA-N-5 differentiation[1]to treat medulloblastoma cells for cell differentiation[2]to treat spheroids for generating time-lapse videos[3]to examine its head- deforming activity under light and dark conditions in Xenopus laevis[4]
- Biochem/physiol Actions: 13-cis-Retinoic acid (RA) has anti-inflammatory and anti-tumor action. The action of RA is mediated through RAR-β and RAR-α receptors. RA attenuates iNOS expression and activity in cytokine-stimulated murine mesangial cells. It induces mitochondrial membrane permeability transition, observed as swelling and as a decrease in membrane potential, and stimulates the release of cytochrome c implicating mechanisms through the apoptosis pathway. These activities are reversed by EGTA and cyclosporin A. RA also increases MMP-1 protein expression partially via increased transcription.
- Features and Benefits: This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
SAFETY INFORMATION
Pictograms
Signal Word
Danger
Hazard Statements
Precautionary Statements
P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
Hazard Classifications
Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Compare Similar Items
Show Difference
Quality Level: 200
Assay: ≥98% (HPLC)
form: powder
technique(s): HPLC: suitable
color: yellow to yellow-orange
mp: 172-175 °C (lit.)
storage temp.: −20°C
SMILES string: [H]\C(C(O)=O)=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C
InChI: 1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
InChI key: SHGAZHPCJJPHSC-XFYACQKRSA-N
Quality Level:
200
Assay:
≥98% (HPLC)
form:
powder
technique(s):
HPLC: suitable
color:
yellow to yellow-orange
mp:
172-175 °C (lit.)
storage temp.:
−20°C
SMILES string:
[H]\C(C(O)=O)=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C
InChI:
1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
InChI key:
SHGAZHPCJJPHSC-XFYACQKRSA-N
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