Applications: Activated PenetratinTM 1 Peptide is a novel tool for peptide and siRNA delivery
It has been successfully used to internalize covalently attached peptides, oligonucleotides, and siRNA
It is sold ready for coupling to peptides or oligonucleotides containing thiol (-SH) functions
Product Overview: PenetratinTM 1 is a patented 16-amino acid peptide corresponding to the third helix of the homeodomain of antennapedeia protein
This peptide is able to translocate across biological membranes by an energy-independent mechanism (1-3) and has been used successfully to internalize covalently attached peptides (4), oligonucleotides (5) and siRNA (6)
Activated PenetratinTM 1 is sold ready for coupling to peptides or oligos containing thiol (-SH) functions
Biotinylated Activated PenetratinTM 1 possesses a biotin group at the C-terminal end allowing the detection of the internalized molecule with an appropriate avidin or streptavidin reagent
Product Description: The Active PenetratinTM 1 Peptide Transfection reagent features a patented 16 amino acid peptide corresponding to the third helix of the homeodomain of the Antennapedia protein (pAntp) from Drosophila melanogaster.
Arginase catalyzes the following reaction: Arginine + H2O → Ornithine + Urea. The enzyme participates in the Krebs-Henseleit urea cycle. It is most highly concentrated in mammalian liver. It is also present in the mammary glands.