NBP226231
Novus Biologicals™ Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 Ligand
Manufacturer: Novus Biologicals™
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Buffer
DMSO
For Use With (Application)
Identity determined by MS, 1H-NMR and 13C-NMR. This product is useful for activation of mouse TLR7 and human TLR7 and TLR8. Stimulation of TLR8 has been achieved with 0.5-5 ug/mL. Use in functional assays reported in scientific literature (PMID 26134251).
Purity
>98%, by HPLC.
Content And Storage
Store at -20°C.
Product Type
Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 Ligand
Quantity
0.5 mg
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Description
- Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 ligand is a low molecular weight synthetic molecule of the Imidazoquinoline family
- It has potent immunostimulatory activity
- It stimulates antibody secretion, cytokine production, protection from apoptosis and CD80 up-regulation
- Species: Human Stimulation of TLR8 has been achieved with 0.5-5μg/mL Recommended Storage Store at 4°C short term
- Aliquot and store at -20°C long term
- Avoid freeze-thaw cycles.
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Buffer: DMSO
For Use With (Application): Identity determined by MS, 1H-NMR and 13C-NMR. This product is useful for activation of mouse TLR7 and human TLR7 and TLR8. Stimulation of TLR8 has been achieved with 0.5-5 ug/mL. Use in functional assays reported in scientific literature (PMID 26134251).
Purity: >98%, by HPLC.
Content And Storage: Store at -20°C.
Product Type: Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 Ligand
Quantity: 0.5 mg
Buffer:
DMSO
For Use With (Application):
Identity determined by MS, 1H-NMR and 13C-NMR. This product is useful for activation of mouse TLR7 and human TLR7 and TLR8. Stimulation of TLR8 has been achieved with 0.5-5 ug/mL. Use in functional assays reported in scientific literature (PMID 26134251).
Purity:
>98%, by HPLC.
Content And Storage:
Store at -20°C.
Product Type:
Imidazoquinoline Resiquimod (R-848), TLR7 and TLR8 Ligand
Quantity:
0.5 mg
Buffer: __
For Use With (Application): Activation of human TLR9
Purity: __
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Product Type: __
Quantity: 2 Vials
Buffer:
__
For Use With (Application):
Activation of human TLR9
Purity:
__
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Product Type:
__
Quantity:
2 Vials
Buffer: __
For Use With (Application): This product is useful for activation of Toll-like Receptor 2 (TLR2). Stimulation of TLR2 has been reported with 1 to 10μL. Note: TLR2 activation at this range of concentrations of Zymosan has also been observed in our product validation tests. Use in In vivo assay and functional inhibition reported in scientific literature (PMID 25846753). Use in ligand activation reported in scientific literature (PMID 25957979). Use in in vitro reported in scientific literature (PMID 27351455).
Purity: __
Content And Storage: Store at -20°C in powder form. Store at -80°C once reconstituted.
Product Type: __
Quantity: 200 mg
Buffer:
__
For Use With (Application):
This product is useful for activation of Toll-like Receptor 2 (TLR2). Stimulation of TLR2 has been reported with 1 to 10μL. Note: TLR2 activation at this range of concentrations of Zymosan has also been observed in our product validation tests. Use in In vivo assay and functional inhibition reported in scientific literature (PMID 25846753). Use in ligand activation reported in scientific literature (PMID 25957979). Use in in vitro reported in scientific literature (PMID 27351455).
Purity:
__
Content And Storage:
Store at -20°C in powder form. Store at -80°C once reconstituted.
Product Type:
__
Quantity:
200 mg
Buffer: __
For Use With (Application): Ligand Activation
Purity: __
Content And Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Product Type: __
Quantity: 2 Vials
Buffer:
__
For Use With (Application):
Ligand Activation
Purity:
__
Content And Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Product Type:
__
Quantity:
2 Vials