Tocris Bioscience™ Gastrin I (human)

Description

• Description Gastrin I (human) is an endogenous peptide produced in the stomach that acts as a selective CCK2 receptor agonist
• Gastrin I stimulates gastric acid secretion and has a mitogenic effect on gastric cells
• Gastrin stimulates gastric epithelial cell proliferation and histamine secretion (EC50 values are 6.2 pM and 0.014 nM, respectively)
• Gastrin I is also used in the culture of stomach, intestine and pancreas organoids
• For more information about using Gastrin I in the generation of gastric organoids see the Human Gastric Organoid Culture Protocol .