35-011
Tocris Bioscience™ Decanoyl-RVKR-CMK
Manufacturer: Tocris Bioscience™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 35-011-Each-of-1 | In Stock | ₹ 24,555.72 |
35-011 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 24,555.72
GST (18%): ₹ 4,420.03
Total Price: ₹ 28,975.75
Quantity
1 mg
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Description
- Decanoyl-RVKR-CMK is a subtilisin/Kex2p-like proprotein convertase inhibitor; blocks activity of all seven convertases (PC1, PC2, PC4, PACE4, PC5, PC7 and furin)
- Abolishes proET-1 processing in endothelial cells; inhibits regulated secretion of the neuronal polypeptide VGF in PC12 cells
- Inhibits cleavage of glycoprotein B of human cytomegalovirus
- Also inhibits cleavage of SARS-CoV-2 spike protein by furin and blocks viral cell entry (IC50 = 57 nM in plaque reduction assay).
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