50-135-0RD
Tocris Bioscience™ AC 710
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 50-135-0RD-Each-of-1 | In Stock | ₹ 1,45,159.00 |
50-135-0RD - Each of 1
In Stock
Quantity
1
Base Price: ₹ 1,45,159.00
GST (18%): ₹ 26,128.62
Total Price: ₹ 1,71,287.62
Purity
>99%
Molecular Weight (g/mol)
562.7
Quantity
50 mg
Description
AC 710
Product Type
AC 710
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Description
- Potent PDGFR family inhibitor (IC50 values are 1.2, 2, 7.7 and 10.5 nM for KIT, FLT3, PDGFRβ and CSF1R respectively; Kd = 1.3 nM for PDGFRα)
- Exhibits >30-fold selectivity over a panel of other kinases and exhibits no activity against cytochrome P450
- Causes tumor regression of leukemia cell xenografts in mice
- Also reduces joint swelling and inflammation in a mouse model of collagen-induced arthritis
- Orally active.
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