55-821

Tocris Bioscience™ TAT-cyclo-CLLFVY

Manufacturer: Tocris Bioscience™

CAS Number: 1446322-66-2

Select a Size

Pack Size SKU Availability Price
Each of 1 55-821-Each-of-1 In Stock ₹ 33,111.72

55-821 - Each of 1

₹ 33,111.72

In Stock

Quantity

1

Base Price: ₹ 33,111.72

GST (18%): ₹ 5,960.11

Total Price: ₹ 39,071.83

Purity

95%

Content And Storage

Store at -20°C

Molecular Weight (g/mol)

Observed M.W.: 2559.1

Structural Form

C111H188N42O24S2

CAS

1446322-66-2

Description

HIF Inhibitors

Quantity

1 mg

Other Options

Image Product Name Manufacturer Price Range
AX35373
1446322-66-2 | TAT-cyclo-CLLFVY
A2B Chem ₹ 23,529.00 - ₹ 1,18,500.60

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Description

  • TAT-cyclo-CLLFVY is a selective HIF-1 dimerization inhibitor
  • Blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50 = 1.3 μM)
  • Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cancer cells in vitro
  • Also reduces tubularization of hypoxic HUVECs.

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