57-101

Tocris Bioscience™ NFAT inhibitor, Cell Permeable

Manufacturer: Tocris Bioscience™

CAS Number: 592517-80-1

Select a Size

Pack Size SKU Availability Price
Each of 1 57-101-Each-of-1 In Stock ₹ 39,100.92

57-101 - Each of 1

₹ 39,100.92

In Stock

Quantity

1

Base Price: ₹ 39,100.92

GST (18%): ₹ 7,038.166

Total Price: ₹ 46,139.086

CAS

592517-80-1

Description

Protein Ser/Thr Phosphatase Inhibitors

Quantity

1 mg

Content And Storage

Store at -20°C

Molecular Weight (g/mol)

Observed M.W.: 3573.15

Structural Form

C147H259N67O36S

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Description

  • NFAT inhibitor, Cell Permeable is an NFAT inhibitor
  • Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs)
  • Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs
  • Reduces inflammation and epithelial damage in a mouse model of colitis
  • In an animal model of Alzheimer's disease NFAT inhibitor improves cognitive and synaptic function, reduces glial activation and lowers amyloid levels; in vitro it reduces glutamate dysregulation and neuron hyperactivity.

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C147H259N67O36S

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