69-205-00U

Tocris™ SAH-SOS1A

Manufacturer: Tocris™

CAS Number: 1652561-87-9

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CAS

1652561-87-9

Description

KRas/SOS1 interaction inhibitor

Molecular Weight (g/mol)

2187.53

Sequence

RRFFGIXLTNXLKTEEGN (Modifications: Arg-1 = N-terminal Ac, X = (S)-2-(4-pentenyl)alanine, X-7 and X-11 stapled together with a double bond)

Content And Storage

Store at -20°C

Formulation

C100H159N27O28

Quantity

500 μg

Other Options

Image Product Name Manufacturer Price Range
BA94257
1652561-87-9 | SAH-SOS1A
A2B Chem ₹ 36,191.88

Description

  • SAH-SOS1A is a KRas/son of sevenless 1 (SOS1) interaction inhibitor
  • Binds within nucleotide binding pocket of KRas (Kd values are 106 - 176 nM for wild type KRas and various KRas mutants)
  • Inhibits nucleotide binding to KRas in a concentration dependent manner
  • Displays cytotoxicity in KRas-driven cancer cell lines and inhibits downstream ERK-MAPK signaling
  • Cell permeable.

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CAS:
1652561-87-9

Description:
KRas/SOS1 interaction inhibitor

Molecular Weight (g/mol):
2187.53

Sequence:
RRFFGIXLTNXLKTEEGN (Modifications: Arg-1 = N-terminal Ac, X = (S)-2-(4-pentenyl)alanine, X-7 and X-11 stapled together with a double bond)

Content And Storage:
Store at -20°C

Formulation:
C100H159N27O28

Quantity:
500 μg

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Fischer Scientific

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Fischer Scientific

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